Notice of Intent to Publish a Funding Opportunity Announcement for Secondary Analyses of Existing Datasets of Tobacco Use and Health (R21 Clinical Trial Not Allowed)

Notice Number: NOT-OD-19-104

Key Dates

Release Date:May 2, 2019
Estimated Publication Date of Funding Opportunity Announcement: August 01, 2019
First Estimated Application Due Date: October 08, 2019
Earliest Estimated Award Date: May 08, 2020
Earliest Estimated Start Date: July 08, 2020

Related Announcements

Issued by
National Institutes of Health (NIH)

Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention (ODP)

National Cancer Institute (NCI)

National Heart, Lung, and Blood Institute (NHLBI)

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

National Institute on Drug Abuse (NIDA)

National Institute of Environmental Health Sciences (NIEHS)


To inform the research community thatThe National Institutes of Health (NIH) Tobacco Regulatory Science Program (TRSP), participating NIH Institutes and Centers (ICs) and the United States Food and Drug Administration (FDA) Center for Tobacco Products (CTP) intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for research proposing the innovative analysis of existing (publicly available) nationally representative U.S. cross-sectional and longitudinal data, to investigate novel scientific ideas and/or to generate new models, systems, tools, methods, or technologies that have the potential for significant impact on biomedical or biobehavioral research in areas relevant to the Food and Drug Administration (FDA) - Center for Tobacco Products (CTP). Other publicly available data sets would be considered depending on the analyses to be conducted; however, nationally representative analyses will receive priority. Applications not using nationally representative data sets will need to provide justification why the data set is unique, and why the research questions cannot be answered from a (publicly available) national representative data set. This FOA encourages the analyses of public use datasets that may inform tobacco regulatory actions in the United States (U.S.).

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in Fall 2019 with an expected application due date in Fall 2019.

This FOA will utilize the R21 activity code.

Research Initiative Details

Funding Information

Estimated Total Funding NIH, via support from the FDA Center for Tobacco products (CTP), intends to fund up to 5 R21s for fiscal year 2020. Future year amounts will depend on availability of funds.
Expected Number of Awards 5
Estimated Award Ceiling The combined budget for the direct cost for the entire project period may not exceed 275,000. No more than $200,000 in direct costs may be requested in a single year.
Primary CFDA Numbers 93.077

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
City or township governments
Special district governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Regional Organization

Applications are not being solicited at this time.


Please direct all inquiries to:

Tobacco Regulatory Science Program (TRSP)
Office of Disease Prevention (ODP)