NIH to Require all Applications to be Submitted in Response to a Funding Opportunity Announcement (FOA) Published in the NIH Guide to Grants and Contracts

Notice Number: NOT-OD-10-134

Update: The following update relating to this announcement has been issued:

  • February 23, 2011 - See Notice NOT-OD-11-048 This Notice redefines the U01 activity code and announces the transition of U01 applications to electronic submission through using the SF424 (R&R) forms for due dates on or after May 25, 2011.

Key Dates
Release Date: September 3, 2010
Effective Date: September 25, 2010

Issued by
National Institutes of Health (NIH)


This Notice is to inform the scientific research community that for applications intended for due dates of September 25, 2010 and beyond, all applications submitted to the National Institute of Health must be submitted in response to a Funding Opportunity Announcement (FOA) published in the NIH Guide to Grants and Contracts. This policy is being implemented to provide fairness across the agency.

Electronic applications are already submitted in response to a FOA. Thus, this policy will primarily affect some ā€œPā€ and ā€œUā€ applications and others still received in paper format. Given this effort to ensure fairness regarding application submissions, the Division of Receipt and Referral at the Center for Scientific Review will no longer accept or assign applications submitted to the NIH without a published FOA in the NIH Guide to Grants and Contracts, beginning with those intended for a due date of September 25, 2010 and beyond.

Applicants are urged to contact their NIH Program Officers if there are questions about this new requirement.


Please direct all inquiries to:

NIH Grants Info
Phone: 301-945-7573
TTY: 301-451-5936