Revised PHS 416-1 (Ruth L. Kirschstein National Research Service Award Application) Now Available

Notice Number: NOT-OD-06-016

Key Dates
Release Date: December 9, 2005

Issued by
National Institutes of Health (NIH), (

EFFECTIVE DATE: The newly revised “Application for an Individual Fellowship Ruth L. Kirschstein National Research Service Award” (PHS 416-1, rev. 10/05) instructions and forms are now available and will be accepted for submission/receipt dates on or after January 5, 2006. Between January 5 and May 9, 2006 applications using either the 6/02 or the 10/05 version of the form will be accepted. All applications received for submission dates on or after May 10 , 2006 must use only the new instructions and forms; otherwise, those applications will be returned to the applicant.

The newly revised instructions and forms are available at The forms available on the website continue to be provided in two formats—MS Word and PDF-fillable using Adobe Acrobat Reader Software. Free Adobe Software may be accessed at Applicants are strongly encouraged to access the instructions and forms via the Internet because they provide valuable links to current policy documents and allow easy navigation of the instructions. This is particularly important with this version due to the interactive format of the instructions. For further information, contact

As in the past, applicants should read the instructions carefully. The following is a list of notable changes.

Notable Changes to the PHS 416-1 (rev. 10/05):

This edition of the PHS 416-1 has been extensively rewritten with a focus on clarity and special emphasis on simplicity and plain language. (Many of the overall changes are identical to those implemented in 2004 in the PHS398.) In addition, there are significant changes to the overall structure of the application. As a result, many of the form pages in the pervious version no longer exist. Applicants are encouraged to use only the form pages provided in the new version. Do not mix old and new versions.

Overall Format Changes

The format has been organized into three distinct, but integrally linked, parts:

Part I: Instructions for Preparing the Application

Part II: Supplemental Instructions for Preparing the Human Subjects Section of the Research Plan

Part III: Policies, Assurances, Definitions and Other Information

Changes of Note to Specific PHS 416-1 Form/Format Pages:

Face Page:

Form Page 2:

Form Page 3:

Applicant/Fellow Biographical Sketch Format Page:

Created a distinct biographical sketch for the applicant/fellow (distinct from the format used by the sponsor/co-sponsor). This consolidates into one concise area information on the applicant/fellow previously scattered throughout the application. Applicants should note this biosketch is unique to applicants/fellows since it includes information on scholastic performance. The Applicant/Fellow must use this format while the sponsor/co-sponsor will continue to use the traditional biosketch format.

Sponsor/Co-Sponsor Biographical Sketch Format Page:

A field has been added for the eRA Commons User Name. This data item is currently optional.

Personal Data Page:

The Applicant/Fellow is now requested to provide only the last four digits of the Social Security Number. While providing this information remains voluntary, it is hoped that by limiting the data to only the last four digits, individuals will be more receptive to providing it. This vital information continues provide the agency with accurate identification, referral, and review of applications and for management of PHS grant programs.

Checklist Form Page:

Specific Changes of Note to the PHS416-1 Instructions

Inquiries on any changes to the forms and instructions may be directed to:

Division of Grants Policy
Office of Policy for Extramural Research Administration
National Institutes of Health
6705 Rockledge Drive, Suite 350
Bethesda, MD 20892
Telephone: (301) 435-0938
FAX: (301) 435-3059

Weekly TOC for this Announcement
NIH Funding Opportunities and Notices

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Research (OER)
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