RELEASE DATE:  June 19, 2003

NOTICE:  NOT-OD-03-049

National Institutes of Health (NIH)

The Office of Extramural Research (OER) is embarking on revisions of 
the Public Health Service Grant Application (PHS 398) and Progress 
Report for Public Health Service Grant (PHS 2590).  The Application and 
Progress Report are used to request Federal assistance for research and 
research-related training.  The forms and instructions are used by the 
following PHS agencies:  National Institutes of Health (NIH), Agency 
for Healthcare Research and Quality (AHRQ), Agency for Toxic Substance 
and Disease Registry (ATSDR), Centers for Disease Control and 
Prevention (CDC), Food and Drug Administration (FDA), Indian Health 
Service (IHS), and the Substance Abuse and Mental Health Services 
Administration (SAMHSA).  

Primary goals of the revision process will be to enhance quality and 
clarity, with special emphasis on streamlining and plain language 
efforts.  Some of the recent policy changes to be incorporated into the 
revision are the following:

o Change in PHS Policy on Humane Care and Use of Laboratory Animals

o New NIH Policy on Data Sharing

o Revised Policy on Submission of Amended Applications

The current PHS 398 and PHS 2590 maintain OMB Clearance through 
5/04/03.  The NIH will publish an announcement in the NIH Guide for 
Grants and Contracts when the new forms and instructions are available 
for use.  There will be a transition period when the current or revised 
forms will be accepted.

Current PHS 398 and 2590 forms and instructions can be viewed at

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