Notice Number: NOT-MH-10-005

Key Dates
Release Date: October 29, 2009 

Issued by
National Institute of Mental Health (NIMH) (http://www.nimh.nih.gov)

Purpose

In addition to the topics listed in Notice NOT-MH-10-001, the NIMH will also support HIV/AIDS-related mental health research in response to PAR-08-112 and PAR-08-113.

Research topics of interest include, but are not limited to, the following:

• Epidemiology, natural history and pathogenesis of HIV-associated neurocognitive disorders (HAND) and neuropsychiatric disorders before and after treatment initiation in adult and pediatric populations
• Impact of viral (clade diversity) and host genetic factors in HIV neuropathogenesis
• Pathophysiology of HIV-associated CNS (central nervous system) disease resulting from opportunistic infections, co-infections and immune reconstitution syndrome
• Neurobehavioral consequences, with respect to in-utero exposure to a dysregulated immune environment and/or antiretroviral medication, of being born to an HIV-positive mother
• Development of common standardized assessment instruments with appropriate norms that can provide reliable and valid measurement of the neurobehavioral consequences of HIV and its treatments throughout the age-span in low and medium resource environments
• Development of interventions to improve neurobehavioral functioning compromised by HIV/AIDS and its associated conditions that can be implemented in low and medium resource environments

All other aspects of PAR-08-112 and PAR-08-113 remain the same

The following institutes are participating in PAR-08-112 and PAR-08-113:

Fogarty International Center (FIC) (http://www.fic.nih.gov)
National Institute on Aging (NIA) (http://www.nia.nih.gov)
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (http://www.niaaa.nih.gov)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (http://www.nichd.nih.gov)
National Institute on Drug Abuse (NIDA) (http://www.nida.nih.gov)
National Institute of Environmental Health Sciences (NIEHS) (http://www.niehs.nih.gov)
National Institute of Mental Health (http://www.nimh.nih.gov)
National Institute of Neurological Disorders and Stroke (NINDS) (http://www.ninds.nih.gov)
Office of Dietary Supplements, Office of the Director (ODS/OD) (http://dietary-supplements.info.nih.gov)
Institute of Neuroscience, Mental Health and Addiction (INMHA/CIHR) (http://www.cihr-irsc.gc.ca/e/8602.html)