Addendum to PAR-08-112 and PAR-08-113 - Brain Disorders in the Developing World: Research Across the Lifespan (R01 and R21, respectively)

Notice Number: NOT-MH-10-001

Update: The following update relating to this announcement has been issued:

  • October 29, 2009 - See Notice NOT-MH-10-005 Second Addendum to PAR-08-112 and PAR-08-113.

Key Dates
Release Date: October 9, 2009

Issued by
National Institute of Mental Health (NIMH) (


The purpose of this notice is to add the National Institute of Mental Health (NIMH) as a participating institute on the Brain Disorders of the Developing World: Research Across the Lifespan (R01 and R21) program announcements PAR-08-113 (R21) and PAR-08-112 (R01).

The National Institute of Mental Health shares interests in the goals of these announcements and is particularly interested in supporting basic, translational, and clinical research to gain a more complete understanding of the genetic, neurobiological, behavioral, environmental, and experiential factors that contribute to neuropsychiatric disorders. PAR-08-113 and PAR-08-112 have the potential to encourage research activities would enable the NIMH to achieve several of the objectives outlined in the NIMH Strategic Plan.

In response to these funding opportunity announcements, the Institute encourages research to that:

  • charts the course of neuropsychiatric disorders over the lifespan in order to understand ideal times and methods for intervention to preempt or treat mental disorders and hasten recovery;
  • identifies malleable and robust risk factors for different phases of the disease trajectory;
  • examines the interactions of neurobiological and environmental/social factors that affect brain development, resulting in behavioral outcomes (e.g., expression of cognitive impairment, coping, adaptation, response to interventions);
  • promotes new psychosocial and biomedical intervention trials that focus on the moderators and predictors (e.g., biological, genetic, behavioral, experiential, environmental) of intervention response and side effects in different patient populations;
  • uses analytical epidemiology to identify potential etiological factors for neuropsychiatric disorders in the populations of interest;
  • develops innovative approaches to tailoring psychosocial and biomedical interventions to different kinds of providers and different intervention settings; and
  • develops and tests novel models and methods on ways to best implement effective mental health interventions: 1) in diverse systems of health care; and 2) to meet the needs of those groups, in a given setting, that typically have less access to quality mental health services (e.g., based on age, sex, stage of illness, race/ethnicity, rural or urban setting, or other factors).

The NIMH-applicable Catalog of Federal Domestic Assistance (CFDA) number is 93.242.

The following institutes are participating in PAR-08-112 and PAR-08-113:

Fogarty International Center (FIC) (
National Institute on Aging (NIA) (
National Institute on Alcohol Abuse and Alcoholism (NIAAA) (
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (
National Institute on Drug Abuse (NIDA) (
National Institute of Environmental Health Sciences (NIEHS) (
National Institute of Mental Health (
National Institute of Neurological Disorders and Stroke (NINDS) (
Office of Dietary Supplements, Office of the Director (ODS/OD) (
Institute of Neuroscience, Mental Health and Addiction (INMHA/CIHR) (

All other aspects of PAR-08-112 and PAR-08-113 remain the same.


Scientific/Research Contact:

Pamela Y. Collins, M.D., M.P.H.
Associate Director for Special Populations
Director, Office for Special Populations & Global Mental Health and
Office of Rural Mental Health Research
National Institute of Mental Health
6001 Executive Boulevard, Room 8125, MSC 9659
Bethesda, MD 20892-9659
Telephone: (301) 443-2847

Grants Management Contact:

Joy R. Knipple
Grants Management Branch
National Institute of Mental Health
6001 Executive Boulevard, Room 6115, MSC 9605
Bethesda, MD 20892-9605
Telephone: (301) 443-8811
FAX: (301) 443-6885