Expiration of Human Brain Project (HBP) Program Announcements

Notice Number: NOT-MH-05-014

Key Dates
Release Date: July 13, 2005

Issued by
National Institute of Mental Health (NIMH), (http://www.nimh.nih.gov)
National Cancer Institute (NCI), (http://www.nci.nih.gov/)
National Heart, Lung, and Blood Institute (NHLBI), (http://www.nhlbi.nih.gov/)
National Institute on Aging (NIA), (http://www.nia.nih.gov/)
National Institute on Alcohol Abuse and Alcoholism (NIAAA), (http://www.niaaa.nih.gov/)
National Institute of Biomedical Imaging and Bioengineering (NIBIB), (http://www.nibib.nih.gov/)
National Institute on Child Health and Human Development (NICHD), (http://www.nichd.nih.gov/)
National Institute on Drug Abuse (NIDA), (http://www.nida.nih.gov/)
National Institute on Deafness and Other Communication Disorders (NIDCD), (http://www.nidcd.nih.gov/)
National Institute of Dental and Craniofacial Research (NIDCR), (http://www.nidcr.nih.gov/)
National Institute of Neurological Disorders and Stroke (NINDS), (http://www.ninds.nih.gov)
National Library of Medicine (NLM), (http://www.nlm.nih.gov/)
National Aeronautics and Space Administration (NASA), (http://www.nasa.gov/)
National Science Foundation (NSF), (http://www.nsf.gov/)
U.S. Department of Energy (DOE), (http://www.energy.gov/)

The Human Brain Project (HBP) was launched in 1993 to develop and support a new science:  neuroinformatics.  Since then, HBP-funded investigators have made many seminal contributions to biomedical informatics.  And, the HBP and its investigators have played a significant role in shaping the current landscape of informatics initiatives at the NIH. 

The HBP has been remarkably successful in establishing the field of neuroinformatics research. It is now time to consider new ways in which this field can best articulate with major informatics initiatives at NIH and ways to best advance research and development of informatics tools and resources for neuroscience.  Such considerations have already begun, and will continue over several months.

In light of this, the current program announcements (PARs) requesting applications for the HBP will not be reissued after they expire on September 23, 2005. The subject program announcements are:

PAR-03-034: Institutional Mentored Research Scientist Development Award for Neuroinformatics (https://grants.nih.gov/grants/guide/pa-files/PAR-03-034.html).

PAR-03-035: The Human Brain Project (Neuroinformatics): Phase I - Feasibility; Phase II – Refinements, Maintenance and Integration (https://grants.nih.gov/grants/guide/pa-files/PAR-03-035.html).

PAR-03-036: Innovative Exploratory Studies and Technology Development in Neuroinformatics Research (R21) (https://grants.nih.gov/grants/guide/pa-files/PAR-03-036.html).

PAR-03-037: Research Core Centers (P30) for Advanced Neuroinformatics Research (https://grants.nih.gov/grants/guide/pa-files/PAR-03-037.html).

Any application submitted after September 22, 2005 should NOT cite any of these expired PARs. This includes new or competitive renewal applications, as well as revisions of applications previously submitted but not funded under the HBP.

Principal Investigators intending to submit new or revised grant applications in the research areas formerly covered by the HBP program announcements may continue to submit R01 applications as investigator-initiated (i.e., leaving as blank, line 2 of the face page of the PHS398 application kit), under the standard submission deadlines. If the scope of research or grant mechanism has substantially changed from a prior HBP application submission, then it should be submitted as a new R01 under the standard deadlines. If the scope of research or grant mechanism has not changed, then a revised or competing continuation application should be submitted using the standard deadlines for revised applications.

Principal Investigators intending to submit new or revised R21 grant applications should now cite the NIH-wide R21 PA (https://grants.nih.gov/grants/guide/pa-files/PA-03-107.html) if the subject matter is appropriate for one of the cosponsoring Institutes/Centers or another appropriate announcement for R21 applications. (All applications submitted for an R21 must cite a relevant Program Announcement: https://grants.nih.gov/grants/guide/notice-files/NOT-OD-05-010.html.) As with the R01s, if the scope of research has substantially changed on an R21, it should be submitted as new and if has not changed, it should be submitted as revised application using the new or revised standard deadlines, respectively.

Principal Investigators who previously submitted or intended to submit P01, P20, P30, or K12 applications in response to the HBP program announcements may not submit these grant mechanisms as investigator initiated applications. Those Principal Investigators who intend to submit these mechanisms can seek other program announcements soliciting these mechanisms, or significantly modify their applications and submit them as R01s or R21s.

Regardless of how Principal Investigators intend to approach grant submissions to the NIH in the research areas formerly covered by the HBP program announcements, all are encouraged to contact their respective program officers regarding such future submissions (http://www.nimh.nih.gov/neuroinformatics/agencycontacts.cfm).


Direct inquiries regarding expiration of these PARs to:

Michael F. Huerta, Ph.D.
Associate Director
National Institute of Mental Health, National Institutes of Health
6001 Executive Blvd. Room 7202, MSC 9645
Bethesda, MD 20892-9645
[Rockville, MD 20852 for express or courier service]
Tel: (301) 443-3563 Fax: (301) 443-1731
Email: mhuert1@mail.nih.gov

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