NHLBI Will No Longer Participate in the Parent NIH Exploratory Developmental Research Grant (R21) Funding Opportunity Announcement

Notice Number: NOT-HL-11-154

Update: The following update relating to this announcement has been issued:

  • January 10, 2012 - See Notice NOT-HL-12-001. Amendment: NHLBI will continue to accept resubmission (A1) R21 applications for the 3/16/12 due date for non-AIDS and for the 5/7/12 due date for AIDS R21s.

Key Dates
Release Date: July 22, 2011

Issued by
National Heart, Lung, and Blood Institute (NHLBI)


The NHLBI is discontinuing funding of new R21 applications in response to the NIH’s Parent Funding Opportunity Announcement (FOA), NIH Exploratory Developmental Research Grant Program (Parent R21). Hence, the NHLBI will no longer be a co-sponsor for the NIH R21 Parent Announcement. The FOA at the time of release of this Notice is PA-10-069. The NHLBI will not accept new (A0) R21 applications in response to the Parent R21 FOA for the Cycle III due dates (October 16, 2011 or January 7, 2012 for AIDS applications) or any date thereafter. The NHLBI will accept resubmission (A1) R21 applications through Cycle I, 2012 (March 16, 2012 or May 7, 2012 for AIDS applications). Starting with Cycle II, 2012 and thereafter, NHLBI will not accept any R21 applications in response to the NIH Exploratory Development Research Grant Program (Parent R21) (PA-11-261).

This Notice does not change NHLBI’s participation in any other FOAs, including those that use the R21 activity code.

In the future, the NHLBI may issue highly targeted Funding Opportunity Announcements for R21 grant applications when scientific opportunities and needs arise that will benefit from the features and requirements of the R21 activity code


Interested parties may contact:

Division of Cardiovascular Diseases

Dr. Michael Lauer
Two Rockledge Center, Room 8124
6701 Rockledge Drive, MSC 7940
Bethesda, MD 20892-7940
Phone: 301-435-0466
Fax: 301-480-7971
Email: lauerm@nhlbi.nih.gov

Division of Lung Diseases

Dr. James Kiley
Two Rockledge Center, Room 10042
6701 Rockledge Drive, MSC 7952
Bethesda, MD 20892-7952
Phone: 301-435-0233
Fax: 301-480-3547
Email: kileyj@nhlbi.nih.gov

Division of Blood Diseases and Resources

Dr. W. Keith Hoots
Two Rockledge Center, Room 9136
6701 Rockledge Drive, MSC 7950
Bethesda, MD 20892-7950
Phone: 301-435-0080
Fax: 301-480-0867
Email: hootswk@nhlbi.nih.gov