Notice Number: NOT-HG-14-017
Release Date: January 10, 2014
National Human Genome Research Institute (NHGRI)
The National Human Genome Research Institute (NHGRI) announces its continued participation in the Ruth L. Kirschstein National Research Service Award (NRSA) institutional research training program (parent T32), and the restructuring of its training programs focused on genomic medicine research for post-doctoral fellows.
In February 2011, NHGRI published its new strategic plan: Charting a course for genomic medicine from base pairs to bedside . The plan was an all-encompassing document for the field of genomics. Based on this document, NHGRI worked towards redefining the specific goals for its research and training and career development programs.
Through a series of advisory panels and workshops (2012 Report, 2012 Presentation, April 2013 Report, September 2013 Report and Video), NHGRI has identified three main goals for the training and career development programs:
1. Expand the base of knowledge in genomic medicine;
2. Continue to support the foundational sciences, with emphasis on acquiring strong quantitative skills;
3. Develop leaders in genomic medicine and genome sciences.
Other overarching principles, recurring themes and recommendations are detailed in the report.
Operationally these goals will be achieved through re-structuring of NHGRI’s training program that will:
For T32 training, NHGRI will create two separate tracks through training grant applications submitted using PA-14-015, parent T32 FOA. The first will maintain the existing program focused on genomic sciences research for graduate students and postdoctoral fellows (See NOT-HG-14-016). The second will create new programs focused on genomic medicine research for postdoctoral fellows (the subject of this Notice).
All NHGRI training programs should provide:
Additional details for the institutional training grant program in genomic sciences are outlined in a parallel NIH Guide Notice (NOT-HG-14-016).
Additional details of the newly-initiated institutional training grant program in genomic medicine are presented below.
The primary objective of this program is to prepare a new generation of leaders in genomic medicine. Individuals in these programs should receive deep and broad training and experiences in the sciences underpinning genomic medicine in order to qualify them to perform independently. This program is open to those with MD or PhD degrees, or their equivalent. Training is accomplished through a combination of formal courses, seminars, supervised research, and training in genomic medicine.
This program will support two career paths for learning new genomic medicine skills: (1) Genomic medicine focus for basic research and/or (2) Genomic medicine focus for clinical research (not for clinical care of patients). An application may include one or both paths. For each path, applicants must clearly describe the goals of the program and a detailed training plan consistent with the goals.
Some of the common elements of a successful training program might include:
Trainees should be appointed for a minimum of two years depending on the knowledge and skills that the trainee brings to the program. It is expected that MDs will commit to a minimum of nine (9) calendar months per year to the program. Up to three (3) months may be used to apply genomics in the clinic, while allowing a mixture of responsibilities that allow maintenance of clinical credentials.
New genomic medicine training programs are limited to six (6) training slots. The number of awards and the number of slots approved will depend upon the quality of the proposed program as determined by peer review, programmatic considerations, and the availability of funds. There will be annual meetings of trainees and program directors. Funds may be requested for trainees and program directors to attend one annual networking meeting in the greater Washington, DC area. Please contact NHGRI program staff for allowable costs. Special Note: To ensure that your application is responsive to this FOA, prior consultation with NHGRI staff is strongly encouraged.
Please direct all inquiries to:
Scientific/Research Contacts Heather A. Junkins, M.S.
Training Program Director
Tina Gatlin, Ph.D.
Training Program Director
Senior Grants Management Specialist
National Human Genome Research Institute/NIH