Notice Number: NOT-HG-14-016
Release Date: January 10, 2014
National Human Genome Research Institute (NHGRI)
The National Human Genome Research Institute (NHGRI) announces its continued participation in the Ruth L. Kirschstein National Research Service Award (NRSA) institutional research training program (parent T32), and the restructuring of its training programs focused on genomic sciences research.
In February 2011, NHGRI published its new strategic plan: Charting a course for genomic medicine from base pairs to bedside. The plan was an all-encompassing document for the field of genomics. Based on this document, NHGRI worked towards redefining the specific goals for its research and training and career development programs.
Through a series of advisory panels and workshops (2012 Report, 2012 Presentation, April 2013 Report, September 2013 Report and Video), NHGRI has identified three main goals for its training and career development programs:
1. Expand the base of knowledge in genomic medicine;
2. Continue to support the foundational sciences, with emphasis on acquiring strong quantitative skills; and
3. Develop leaders in genomic medicine and genome sciences.
Other overarching principles, recurring themes and recommendations are detailed in the report.
Operationally these goals will be achieved through restructuring of NHGRI’s training program that will:
For T32 training, NHGRI will create two separate tracks through training grant applications submitted using PA-14-015, the parent T32 FOA. The first will maintain the existing program focused on genomic sciences research for graduate students and postdoctoral fellows (the subject of this Notice). The second will create new programs focused on genomic medicine research for postdoctoral fellows (See NOT-HG-14-017).
All NHGRI training programs should provide:
Additional details for the institutional training grant program in genomic medicine are outlined in a parallel NIH Guide Notice (link to NOT-HG-14-017).
Additional details for the institutional training grant program in genomic science are presented below.
The program objective is to develop research leaders in genomic sciences. Training programs should ensure that trainees will develop a knowledge base and skill sets in two areas: 1) the biomedical sciences (includes the biological sciences, engineering, technology development, clinical discovery, etc.), 2) and the quantitative sciences (includes mathematics, statistics, bioinformatics, computational biology, etc). Training should be acquired broadly across both areas and in depth in one or more areas of specialty. A greater emphasis should be placed on in-depth training in a quantitative sciences specialty. Applications will likely be more successful from institutions that have many and varied ongoing genomic research projects, and in which trainees will have access to large and complex datasets, including genomic, proteomic, and patient and clinical data, due to the essential opportunities that such resources will provide to trainees.
For applicants who propose to provide training at the pre-doctoral and post-doctoral levels, a detailed training plan must be provided. Some of the common elements of a successful training program might include:
New training programs will be limited to 10 trainees. Due to budget constraints and the need to provide opportunities to additional training programs, ongoing training programs may experience a reduction in the number of approved trainees. In both cases, final decisions about the number of training slots will depend upon the quality of the proposed program as determined by peer review, programmatic considerations, and the availability of funds. There will be annual meetings of trainees and program directors. Funds may be requested for trainees and program directors to attend one annual networking meeting in the greater Washington, DC area. Please contact program staff for allowable costs.
Special Note: To ensure that your application is responsive to this FOA, prior consultation with NHGRI staff is strongly encouraged.
Please direct all inquiries to:
Senior Grants Management Specialist
National Human Genome Research Institute