Notice of Intent to Publish a Funding Opportunity Announcement for Medical Rehabilitation Research Resource (P2C Clinical Trial Optional)

Notice Number: NOT-HD-18-026

Key Dates

Release Date:January 22, 2019
Estimated Publication Date of Funding Opportunity Announcement: January 30, 2018
First Estimated Application Due Date: March 30, 2019
Earliest Estimated Award Date: December 01, 2019
Earliest Estimated Start Date: December 01, 2019

Related Announcements

Issued by

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)


The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), through the National Center for Medical Rehabilitation Research (NCMRR), with support from NINDS, NIBIB, NIDCD, and NINR, intends to promote research infrastructure by publishing a Funding Opportunity Announcement (FOA) to solicit P2C applications. 

This Notice encourages investigators with expertise and insights in Medical Rehabilitation Research and allied fields to develop research infrastructure applications to promote collaborations with the research community. In response to this FOA, applicants should propose a research infrastructure center that provide access to collateral expertise in biomedical, behavioral, engineering, and/or psychosocial fields that are particularly relevant to medical rehabilitation research and the needs of people with chronic physical disabilities. Specifically, the NIH is interested in addressing gaps in the rehabilitation research portfolio and is particularly interested in the following high-priority areas: pediatric rehabilitation; personalized medicine approaches; family, caregiver, and community support; implementation and dissemination research; clinical trial design and combinatorial therapies; strategies to explore and validate combination therapies; and, technology to track real-world outcomes.  

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. 

The FOA is expected to be published in Winter with an expected application due date in Spring 2019.

This FOA will utilize the P2C activity code. Details of the planned FOA are provided below.

Research Initiative Details

Applicants should propose a program of research resources and collaborative opportunities in a specific content area. This may be accomplished through a combination of didactic interactions (workshops, courses, written material, and websites), consultations, collaborations, and pilot funding. In addition, the research core may support local institutional activities related to technique development, adaptation, and validation. Although high-priority areas are listed above, additional areas may be proposed provided they are timely and appropriate for promoting medical rehabilitation research and improving outcomes for people with disabilities. In addition, an infrastructure applicant may also propose to take on the role of a coordinating center to support a web portal, promote the overall infrastructure program, promote trans-center activities, and document overall infrastructure outcome data. Centralized research infrastructure will enhance the capability of medical rehabilitation investigators to understand mechanisms of functional recovery, develop therapeutic strategies, and improve the lives of people with disabilities. This FOA represents the fourth renewal of this highly successful and evolving research infrastructure program. 

In the context of this FOA, medical rehabilitation includes support and treatment for chronic conditions such as stroke, brain or spinal cord injury, orthopedic and joint conditions, developmental and degenerative disorders, cardiovascular and pulmonary rehabilitation, and support for cancer survivors. Investigations supported by NCMRR and other NIH Institutes explore research at various levels: reducing pathophysiology, minimizing physical impairments, enhancing functional recovery, promoting learning and adaptation, preventing secondary complications, reducing disability and societal barriers, and enhancing overall health and quality of life. Research across these domains requires the integration of biological, engineering, and socio-behavioral approaches to understand the basis of chronic conditions, potential secondary complications, restorative therapies, and the interaction of the individual with his/her environment. A multidisciplinary approach to these goals is fundamental to medical rehabilitation practice. 

Funding Information

Estimated Total Funding Issuing IC and partners intend to commit an estimated total of at least $6.850 million in FY2020 (contingent upon the NIH appropriations).
Expected Number of Awards The issuing IC and partner components intend to support at least five awards.
Estimated Award Ceiling Applicants may request up to $750,000 direct costs per year.
Primary CFDA Numbers 93.865

Anticipated Eligible Organizations

Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
Indian/Native American Tribal Government (Federally Recognized)
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)


Applications are not being solicited at this time. 



Please direct all inquiries to:

Ralph Nitkin, PhD
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)