Notice Number: NOT-DK-17-002
Key Dates
Release Date: November 23, 2016
Issued by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Heart, Lung, and Blood Institute (NHLBI)
Purpose
In a continuing effort to support emerging fields in nonmalignant hematology research, NIDDK and NHLBI are pleased to announce continued funding and additional research objectives for PAS-16-033 "Stimulating Hematology Investigation: New Endeavors (R01)".
The collaborative SHINE program (PAS-16-033) has set aside approximately $1,750,000 between the two Institutes to make approximately 6-8 awards in addition to those funded in accordance with FY2018 funding policies. These funds will be used for highly meritorious applications received in response to PAS-16-033 in the specific scientific areas mentioned below.
(1) As announced in the inauguration of the SHINE program (PAS-10-046, the predecessor of PAS-16-033)), specific topic areas will change to meet timely needs and opportunities for hematology research progress. Applicants are encouraged to contact NIDDK or NHLBI Scientific/Research staff to discuss plans for preparation of an R01 application.
(2) With the publication of this Notice, the following SHINE-eligible topics are encouraged:
Regulatory Determinants of Hematopoietic Stem Cell Fate. See: NOT-DK-12-007.
Role of Noncoding RNA in Hematopoiesis. See NOT-DK-14-001.
Role of Macrophages in Blood Cell Development. See NOT-DK-15-011.
Effects of Aging on Hematopoiesis. See NOT-DK-16-007.
Metabolic Modulators of Hematopoiesis. See next paragraph.
(3) The addition of the "Metabolic Modulators of Hematopoiesis" topic was informed by the Mitochondrial Biology Symposium: Novel Roles of Mitochondria in Health and Disease held May 19-20, 2016 by NIDDK in collaboration with NHLBI. Cellular metabolism plays critical roles in energy production, the maintenance of a reservoir of cellular building blocks such as amino and nucleic acids, and coordinating stress and survival responses in most cell types. Hematopoietic cells are likely to require specialized coordination of metabolic processes across their unique stages of development and across their lifespan. Relevant research questions for this new SHINE topic include, but are not limited to:
All other aspects of this Funding Opportunity Announcement remain the same.
Inquiries
Please direct all inquiries to:
Cindy N. Roy, Ph.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Telephone: (301) 594-8805
Email: cindy.roy@nih.gov
Manjit Hanspal, Ph.D.
Molecular, Cellular, and Systems Blood Science Branch
Division of Blood Diseases and Resources
National Heart, Lung, and Blood Institute
Telephone: (301) 435-0050
Email: hanspalm@nhlbi.nih.gov
John W. Thomas, Ph.D.
National Heart, Lung, and Blood Institute
Telephone: (301) 435-0065
Email: thomasj@nhlbi.nih.gov