Notice of Intent to Publish a Funding Opportunity Announcement for INIA Research Project (U01 Clinical Trial Optional)
Notice Number:

Key Dates

Release Date:
June 11, 2020
Estimated Publication Date of Funding Opportunity Announcement:
October 15, 2020
First Estimated Application Due Date:
May 18, 2021
Earliest Estimated Award Date:
February 21, 2022
Earliest Estimated Start Date:
March 21, 2022
Related Announcements

NOT-AA-20-14 - Notice of Intent to Publish a Funding Opportunity Announcement for INIA Administrative Resource (U24 Clinical Trial Not Allowed)

NOT-AA-20-15 - Notice of Intent to Publish a Funding Opportunity Announcement for INIA Research Resource (U24 Clinical Trial Not Allowed)

Issued by

National Institute on Alcohol Abuse and Alcoholism (NIAAA)


The National Institute on Alcohol Abuse and Alcoholism intends to renew an initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for collaborative research projects (U01) to investigate brain mechanisms of excessive alcohol drinking and related phenotypes associated with alcohol use disorder (AUD). The U01s are components of a Consortium on the Integrative Neuroscience Initiative on Alcoholism (INIA).

This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

The FOA is expected to be published in Summer/Fall 2020 with an expected application due date in Winter/Spring 2021.

This FOA will utilize the U01 activity code. Details of the planned FOA are provided below.

Research Initiative Details

This Notice encourages investigators with expertise and insights into this area of the neurobiology of Alcohol Use Disorder (AUD) to begin to consider applying for this new FOA.

With this Funding Opportunity Announcement FOA, NIAAA seeks to support 2 consortia to continue to advance integrative research efforts on mechanistic hypotheses pertaining to the development and remediation of excessive drinking associated with AUD. The focus should be on current research gaps which include neuroimmune functions and related mechanisms, stress systems, emotional and cognitive characteristics such as negative affect (e.g., hyperkatifeia, anxiety, emotional pain, dysphoria), and cognitive control dysfunction contributing to alcohol addiction. In addition, we encourage research addressing hypotheses addressing interactions between alcohol and other relevant causal influences on the development of AUD pathology which could include conditions such as trauma, pain conditions and social isolation. Both consortia supported under this initiative will be expected to collaborate with one another through joint meetings and resource sharing.

Each consortium should be organized around a central theme, with individual projects addressing a targeted subset of objectives. Projects should not only be relevant to the overall consortium theme, but also contribute data and analyses that are used by other consortium components to address hypotheses which integrate different levels of analysis or mechanistically related manifestations of AUD

Funding Information
Estimated Total Funding

$10 million will be committed to the proposed FOA and companion FOAs. $5 million will be dedicated to each consortium. For the proposed FOA, up to $8 million will be committed with $4 million dedicated to each of 2 consortia.

Expected Number of Awards


Estimated Award Ceiling

Application budgets are not limited but need to reflect the actual needs of the proposed project.

Primary CFDA Numbers


Anticipated Eligible Organizations
Public/State Controlled Institution of Higher Education
Private Institution of Higher Education
Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education)
Small Business
For-Profit Organization (Other than Small Business)
State Government
Indian/Native American Tribal Government (Federally Recognized)
County governments
Independent school districts
Public housing authorities/Indian housing authorities
Indian/Native American Tribally Designated Organization (Native American tribal organizations (other than Federally recognized tribal governments)
U.S. Territory or Possession
Indian/Native American Tribal Government (Other than Federally Recognized)
Non-domestic (non-U.S.) Entity (Foreign Organization)
Regional Organization
Eligible Agencies of the Federal Government

Applications are not being solicited at this time.


Please direct all inquiries to:

Abraham P. Bautista, Ph.D.

National Institute on Alcohol Abuse and Alcoholism (NIAAA)


Weekly TOC for this Announcement
NIH Funding Opportunities and Notices