Small Business Innovation Research (SBIR) Program Contract Solicitation (PHS 2013-1) Now Available

Notice Number: NOT-OD-12-137

Update: The following update relating to this announcement has been issued:

Key Dates
Release Date: August 15, 2012
Contract Proposal Receipt Date: November 13, 2012

Issued by
National Institutes of Health (NIH)
Centers for Disease Control and Prevention (CDC)

Purpose

Innovative technologies and methodologies fuel progress in biomedical and behavioral research and represent an increasingly important area of the economy. The Small Business Innovation Research (SBIR) program provides support for research and development (R&D) of new or improved technologies and methodologies that have the potential to succeed as commercial products.
 
The purpose of this notice is to (1) announce the issuance of the Solicitation of the National Institutes of Health and the Centers for Disease Control and Prevention for Small Business Innovation Research Contract Proposals (PHS 2013-1) with a receipt date of November 13, 2012; and (2) inform the public about the opportunities that the SBIR program offers to small business concerns as well as to scientists at research institutions.

The SBIR legislation requires the Public Health Service (PHS), Department of Health and Human Services, and certain other Federal agencies to reserve 2.6 percent (for FY2012) of their extramural research or R&D budgets for an SBIR program. (The NIH SBIR set-aside requirement for FY 2012 is $632 million.)

The offeror organization must be a small business concern as defined by the Small Business Administration and described in the Contract Solicitation. The primary employment of the principal investigator MUST be with the small business concern at the time of award and during the conduct of the proposed project. In accord with the intent of the SBIR program to increase private sector commercialization of innovations derived from Federal R&D, scientists at research institutions can play an important role in an SBIR project by serving as consultants and/or subcontractors to the small business concern. Generally, up to 1/3 of the Phase I budget may be spent on consultant and/or subcontractual costs, and, generally, up to 1/2 of the Phase II budget may be spent on such costs. In this manner, a small business concern with limited expertise and/or research facilities may benefit from teaming with a scientist(s) at a research institution; for the scientist(s) at a research institution, this team effort provides support for R&D not otherwise obtained. The SBIR program consists of the following three phases:

PHASE I: The objective of this phase is to determine the scientific and technical merit and feasibility and potential for commercialization of the proposed research or R&D efforts and the quality of performance of the small business concern, before consideration of further Federal support in Phase II. Generally, Phase I SBIR awards do not exceed $150,000 for direct costs, Facilities and Administrative (F&A) costs, and negotiated fixed fee for a period generally not to exceed six months.

PHASE II: The objective of this phase is to continue the research or R&D efforts initiated in Phase I. Funding shall be based on the results of Phase I and the scientific and technical merit and commercial potential of the Phase II proposal. Phase I contractors are eligible to apply for Phase II grant or contract funding and will be informed of Phase II opportunities. (However, see "Fast-Track" Initiative below.) Generally, Phase II awards do not exceed $1,000,000 for direct costs, F&A costs, and negotiated fixed fee for a period generally not to exceed two years.

PHASE III: The objective of this phase is for the small business concern to pursue, with non-SBIR funds, the commercialization of the results of the research or R&D funded in Phases I and II.

"FAST-TRACK" INITIATIVE: (Applicable only to proposals submitted to the NIH and only if an awarding component indicates that it is accepting Fast-Track proposals for a particular topic.)

The Fast-Track initiative is an opportunity for small business concerns to submit both a Phase I and Phase II proposal for concurrent peer review. This initiative also has the potential to minimize any funding gap between Phase I and Phase II. Proposals must be prepared in accordance with Phase I and Phase II proposal preparation instructions.

Following are the research topics contained in the PHS 2013-1 Solicitation:

National Institutes of Health (NIH)

National Cancer Institute (NCI)
313      RNAi Cancer Therapeutics using Nanotechnology
314      Development of Human Tissue Culture Systems that Mimic the Tumor Microenvironment
315      Development of Companion Diagnostics: Enabling Precision Medicine in Cancer Therapy
316      Development of CTC Isolation Technologies Enabling Downstream Single Cell Molecular Analysis
317      Wound Healing Preparations Incorporating Nitric Oxide-Releasing Materials (NIH Technology Transfer)
318      Test to Predict Effectiveness of Docetaxel Treatment for Prostate Cancer (NIH Technology Transfer)
319      Technology to Generate Anti-Peptide Capture Reagents for Affinity-Enriched Proteomic Studies
320      High Quality Cancer-Related Standards for Metabolomics Research
321      Chemically Defined Glycan Libraries for Reference Standards and Glycomics Research
(Joint NCI-NIGMS Program)
322      Real-Time Integration of Sensor and Self-Report Data for Clinical and Research Applications
323      Development of Radiation Modulators for Use During Radiotherapy
324      Novel Imaging Agents to Expand the Clinical Toolkit for Cancer Diagnosis, Staging, and Treatment
325      Innovative Radiation Sources for Advanced Radiotherapy Equipment

National Center for Advancing Translational Sciences (NCATS)
001      Visualizing Knowledge about Human Health and the Pathways of Translation
002      Biomarker Study for Creatine Transporter Defect Disorders
003      Automated Instrument to Clean Microtiter Plates
004      Assay Development for High-Throughput Screening of Chemicals of Toxicological Concern

National Heart, Lung and Blood Institute (NHLBI)
072      New Methods to Detect and Assess Myocardial Fibrosis
073      Evaluating Obstructive Sleep Apnea Dental Device Treatment Compliance
074      Improving Safety and Efficacy of Red Blood Cells for Transfusion
075      Dedicated Pediatric Cardiac MRI Receive Coils
076      MRI Myocardial Biopsy Forceps
077      Passive MRI Guidewire
078      Transthoracic Cardiac Access Ports and Closure Devices
079      Bioabsorbable Stents for Pediatric Pulmonary Artery Stenosis and Aortic Coarctation
080      Fluorescent Nanodiamonds for In Vitro and In Vivo Biological Imaging

National Institute of Allergy and Infectious Diseases (NIAID)
021      Aerosolized Delivery of Anti-Tubercular Drugs
022      Development of Long-Acting Formulations of HIV Anti-Retrovirals
023      Improved Formulations for Approved First and Second line anti-Tuberculosis (TB) Drugs
024      Integrated Multiplex Medical Diagnostics Platforms for Infectious Diseases

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
023      Neural Interfaces: Improving Functional Outcomes

National Institute on Drug Abuse (NIDA)
147      A Mobile Application to Help Patients Take their Pill Medications as Prescribed: Improving Medication Adherence
148      Products for at-home Deactivation of Psychoactive Prescription Medicines
149      Development of Predictive in vivo Screening Systems for Phenotypic Drug Discovery for Smoking Cessation
150      Video Game Targeting Relapse Prevention in Youth with Substance Use Disorders

Centers for Disease Control and Prevention (CDC)

Center for Global Health (CGH)
003      Diagnostic Needs for Neglected Tropical Diseases (NTD) Programs
004      Rapid Screening Tests to Prevent Congenital Infections and Ensure Blood Safety
005      Development of Diagnostic Tests for Strongyloidiasis and Schistosomiasis

National Center on Birth Defects and Developmental Disabilities (NCBDDD)
016      Improving Data, Improving Care, Making it Count
017      Smartphone Application for Global Birth Defects Surveillance

National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP)
033      A Mobile Phone Application (“App”) for Advancing Teen Pregnancy Prevention

National Center for Emerging Zoonotic and Infectious Diseases (NCEZID)
003      Development of Nanoparticle Dengue Diagnostic Tests
004      Development of Tests in a Standardized Kit Format for Diagnosis of Arboviral Infections in Resource-Limited, Primary Health Care Setting
005      Reducing Antimicrobial Resistance through Improved use of Laboratory Testing Information in Healthcare Facilities

National Center for HIV/AIDs, Viral Hepatitis, STD, and TB Prevention (NCHHSTP)
034      Development of Biomedical Devices to Elicit Durable Protective Immunity against HIV
035      Development of a Portable Multiplex Assay for Determination of Recent HIV-1 Infection
036      Testing the Efficacy of Combination HIV Prevention Strategies in Nonhuman Primates

National Center for Immunization and Respiratory Diseases (NCIRD)
025      Development of an Inactivated Rotavirus Vaccine for Use in Global Immunization
026      Thermostable Dry Measles Vaccine Formulation for Sublingual Administration

Office of Public Health Preparedness and Response (OPHPR)
002      Improved Methods for Collection, Preservation, and Transportation of Biological Specimens

Inquiries

Eligibility requirements, definitions, submission procedures, review considerations, contract proposal forms and instructions, and other pertinent information, including the "Fast-Track" Initiative, are contained in the Solicitation (PHS 2012-1). The Solicitation, including contract proposal forms, is available electronically through the NIH "Small Business Research Funding Opportunities” Web site. See SBIR Phase I Contract Solicitation PHS 2013-1 (PDF [http://grants.nih.gov/grants/funding/SBIRContract/PHS2013-1.pdf] or MS Word [http://grants.nih.gov/grants/funding/SBIRContract/PHS2013-1.doc]). Be sure to use the appropriate CONTRACT PROPOSAL forms as they differ from the SF424 (R&R) GRANT application forms.

Note: The SBIR Phase I Contract Solicitation is available ONLY via electronic means. Potential offerors are encouraged to check the NIH Small Business Research Funding Opportunities Web site for updates on the program. Any updates or corrections to the Solicitation will be posted there.

Contracting Officers

Any small business concern that intends to submit an SBIR contract proposal under this Solicitation should provide the appropriate contracting officer(s) with early, written notice of its intent, giving its name, address, e-mail, telephone, and topic number(s). If a topic is modified or canceled before the Solicitation closes, only those companies that have expressed such intent will be notified.

National Institutes of Health (NIH)

National Cancer Institute (NCI)

Ms. Anita Hughes
Phone: (301) 435-3805
Fax: (301) 480-0309
Email: anita.hughes@nih.gov

National Center for Advancing Translational Sciences (NCATS)

Mr. Richard Phillips
Phone: (301) 402-6462
Fax: (301) 480-3432
E-mail:  phillipr@nhlbi.nih.gov

National Heart, Lung, and Blood Institute (NHLBI)

Mr. John Taylor
Phone: (301) 435-0327
Fax: (301) 480-3338
E-mail: taylorjc@nhlbi.nih.gov

National Institute of Allergy and Infectious Diseases (NIAID)

Mr. Richard Hartmann
Phone: (301) 496-0612
Fax: (301) 480-4675
E-mail:  Richard.Hartmann@nih.gov

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Lynn Salo, Contracting Officer
Phone: (301) 435-6962
Fax: (301) 402-3676
Email: salol@mail.nih.gov

National Institute on Drug Abuse (NIDA)

Mr. Brian O’Laughlin
Phone: (301) 443-6677
Fax: (301) 443-7595
Email: bo50d@nih.gov

Centers for Disease Control and Prevention (CDC)

For general administrative SBIR program questions, contact:

Juliana Cyril, Ph.D., M.P.H.
Deputy Director, Office of Science Quality
Office of the Associate Director for Science
Phone: (404) 639-4639
Fax: (404) 639-4903
E-mail:  JCyril@cdc.gov

Sean David Griffiths, M.P.H.
Office of Science Quality
Office of the Associate Director for Science
Phone: 404-639-4641
Fax: 404-639-4903
E-mail:  SGriffiths@cdc.gov

Center for Global Health (CGH)

Carlos Smiley
Contracting Officer
Phone: (770) 488-1517
Fax: (770) 488-2688
E-mail: CSmiley1@cdc.gov

National Center for Birth Defects and Developmental Disabilities (NCBDDD)

Natasha Y. Rowland
Contracting Officer
Phone: (770) 488-2601
Fax: (770) 488-2671
Email:  hee5@cdc.gov

National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP)

Natasha Y. Rowland
Contracting Officer
Phone: (770) 488-2601
Fax: (770) 488-2671
Email:  hee5@cdc.gov

National Center for Emerging Zoonotic and Infectious Diseases (NCEZID)

Theresa Routh-Murphy
Contracting Officer
Phone: (770) 488.2173
E-mail:  TRN3@cdc.gov

National Center for HIV/AIDs, Viral Hepatitis, STD, and TB Prevention (NCHHSTP)

Julio Lopez
Contracting Officer
Phone: (770) 488-2892
Fax: (770) 488-2868
E-mail: jlopez3@cdc.gov

National Center for Immunization and Respiratory Diseases (NCIRD)

Alan Sims
Contracting Officer, Lead
Phone: (770) 488-2647
Fax: (770) 488-2670
E-mail:  ASims1@cdc.gov

Office of Public Health Preparedness and Response (OPHPR)

Donna Myler
Contracting Officer, Lead
Phone: (770) 488-2861
Fax: (770) 488-2670
E-mail:  DMyler@cdc.gov

Those interested in the PHS small business research GRANT programs, where investigator-initiated research ideas are encouraged, are invited to access the Omnibus Solicitation of the Public Health Service for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Grant Applications (PHS 2012-2). There is one grant application due date (December 5, 2012) remaining for calendar year 2012.

To understand better the differences between grants and contracts, see Contracts vs. Grants: What's the difference?


Weekly TOC for this Announcement
NIH Funding Opportunities and Notices


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