Notice of Change in Application Due Date for PAR-25-032 "NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)"
Notice Number:
NOT-HL-27-003

Key Dates

Release Date:
October 20, 2026
Effective Date:
08/29/2026

Related Announcements

December 18, 2024 - NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional). See NOFO PAR-25-032.

Issued by

National Heart, Lung, and Blood Institute (NHLBI)

Purpose

The purpose of this notice is to inform potential applicants of a change in the key dates for the Notice of Funding Opportunity (NOFO) PAR-25-032 "NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)". Specifically, 1 additional receipt date has been added for new applications and resubmission/revision applications. The NOFO will now expire on March 17, 2027. 

The following sections of PAR-25-032 have been updated in bold italics to reflect the additional receipt dates and new expiration date. 

Currently Reads

Part 1. Overview Information

Key Dates

The following table includes NIH standard due dates marked with an asterisk.

Application Due Dates

Review and Award Cycles

New

Renewal / Resubmission / Revision (as allowed)

AIDS - New/Renewal/Resubmission/Revision, as allowed

Scientific Merit Review

Advisory Council Review

Earliest Start Date

February 16, 2025 *

March 16, 2025 *

May 07, 2025 *

July 2025

October 2025

December 2025

June 16, 2025 *

July 16, 2025 *

September 07, 2025 *

November 2025

January 2026

April 2026

October 16, 2025 *

November 16, 2025 *

January 07, 2026 *

March 2026

May 2026

July 2026

February 16, 2026 *

March 16, 2026 *

May 07, 2026 *

July 2026

October 2026

December 2026

June 16, 2026 *

July 16, 2026 *

Not Applicable

November 2026

January 2027

April 2027

October 16, 2026 *

November 16, 2026 *

Not Applicable

March 2027

May 2027

July 2027

All applications are due by 5:00 PM local time of applicant organization. 

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date

January 08, 2027

Due Dates for E.O. 12372

Not Applicable

Revised to Read

Part 1. Overview Information

Key Dates

The following table includes NIH standard due dates marked with an asterisk.

Application Due Dates

Review and Award Cycles

New

Renewal / Resubmission / Revision (as allowed)

AIDS - New/Renewal/Resubmission/Revision, as allowed

Scientific Merit Review

Advisory Council Review

Earliest Start Date

February 16, 2025 *

March 16, 2025 *

May 07, 2025 *

July 2025

October 2025

December 2025

June 16, 2025 *

July 16, 2025 *

September 07, 2025 *

November 2025

January 2026

April 2026

October 16, 2025 *

November 16, 2025 *

January 07, 2026 *

March 2026

May 2026

July 2026

February 16, 2026 *

March 16, 2026 *

May 07, 2026 *

July 2026

October 2026

December 2026

June 16, 2026 *

July 16, 2026 *

Not Applicable

November 2026

January 2027

April 2027

October 16, 2026 *

November 16, 2026 *

Not Applicable

March 2027

May 2027

July 2027

February 16, 2027 *

March 16, 2027 *

Not Applicable

July 2027

October 2027

December 2027

All applications are due by 5:00 PM local time of applicant organization. 

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Expiration Date

March 17, 2027

Due Dates for E.O. 12372

Not Applicable

All other aspects of the NOFO remain the same.

Inquiries

Please direct all inquiries regarding this Notice to:

Scientific/Research Contact(s)

Division of Cardiovascular Sciences
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-003

Division of Blood Diseases and Resources, Grant Resources (Non-Clinical Trial Research)
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-003

Division of Blood Diseases and Resources, Clinical Trials
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-003

Division of Lung Diseases
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-003

Center for Translation Research and Implementation Science
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-003

Financial/Grants Management Contact(s)

Office of Grants Management
National Heart, Lung, and Blood Institute (NHLBI) 
Email: [email protected]
Subject: NOT-HL-27-003