December 05, 2024 - NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required). See NOFO PAR-25-025.
December 05, 2024 - NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required). See NOFO PAR-25-026.
National Heart, Lung, and Blood Institute (NHLBI)
The purpose of this notice is to inform potential applicants of a change in the key dates for notices of funding opportunity (NOFO) PAR-25-025 "NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)" and PAR-25-026 "NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)". Specifically, 1 additional receipt date has been added for new applications and resubmission/revision applications. The NOFO will now expire on February 4, 2027.
The following sections of PAR-25-025 and PAR-25-026 have been updated in bold italics to reflect the additional receipt date and new expiration date.
Part 1. Overview Information
Key Dates
The following table includes NIH standard due dates marked with an asterisk.
Application Due Dates | Review and Award Cycles | ||||
|---|---|---|---|---|---|
New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
February 03, 2025 | February 03, 2025 | May 07, 2025 * | July 2025 | October 2025 | December 2025 |
June 04, 2025 | June 04, 2025 | September 07, 2025 * | November 2025 | January 2026 | April 2026 |
October 02, 2025 | October 02, 2025 | January 07, 2026 * | March 2026 | May 2026 | July 2026 |
February 03, 2026 | February 03, 2026 | May 07, 2026 * | July 2026 | October 2026 | December 2026 |
June 04, 2026 | June 04, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
October 02, 2026 | October 02, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
All applications are due by 5:00 PM local time of applicant organization.
Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
Expiration Date
January 08, 2027
Due Dates for E.O. 12372
Not Applicable
Part 1. Overview Information
Key Dates
The following table includes NIH standard due dates marked with an asterisk.
Application Due Dates | Review and Award Cycles | ||||
|---|---|---|---|---|---|
New | Renewal / Resubmission / Revision (as allowed) | AIDS - New/Renewal/Resubmission/Revision, as allowed | Scientific Merit Review | Advisory Council Review | Earliest Start Date |
February 03, 2025 | February 03, 2025 | May 07, 2025 * | July 2025 | October 2025 | December 2025 |
June 04, 2025 | June 04, 2025 | September 07, 2025 * | November 2025 | January 2026 | April 2026 |
October 02, 2025 | October 02, 2025 | January 07, 2026 * | March 2026 | May 2026 | July 2026 |
February 03, 2026 | February 03, 2026 | May 07, 2026 * | July 2026 | October 2026 | December 2026 |
June 04, 2026 | June 04, 2026 | Not Applicable | November 2026 | January 2027 | April 2027 |
October 02, 2026 | October 02, 2026 | Not Applicable | March 2027 | May 2027 | July 2027 |
February 03, 2027 | February 03, 2027 | Not Applicable | July 2027 | October 2027 | December 2027 |
All applications are due by 5:00 PM local time of applicant organization.
Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
Expiration Date
February 04, 2027
Due Dates for E.O. 12372
Not Applicable
All other aspects of the NOFO remain the same.
Please direct all inquiries regarding this Notice to:
Scientific/Research Contact(s)
Division of Lung Diseases
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-002
Division of Blood Diseases and Resources
Clinical Trials
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-002
Division of Cardiovascular Sciences
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected], [email protected]
Subject: NOT-HL-27-002
Financial/Grants Management Contact(s)
Office of Grants Management
National Heart, Lung, and Blood Institute (NHLBI)
Email: [email protected]
Subject: NOT-HL-27-002