NIH Grants Policy Statement
The National Institutes of Health Grants Policy
Statement (NIHGPS) is intended to make available to NIH grantees, in a
single document, the policy requirements that serve as the terms and conditions
of NIH grant awards. This document also is designed to be useful to those
interested in NIH grants by providing information about NIH—its organization,
its staff, and its grants process. The NIHGPS is available online at https://grants.nih.gov/grants/policy/policy.htm#gps.
This version includes many links within the document as well as links to some
web resources outside of this document. Users are strongly encouraged to use
the on-line version of this document to benefit from these links.
The NIHGPS has three parts, which allows general
information, application information, and other types of reference material to
be separated from legally binding terms and conditions:
- Part I: NIH Grants—General Information. Part I (chapters 1 and 2) contains a
glossary defining commonly used terms and abbreviations used throughout the
document; describes NIH and its relationship to other organizations within the
Department of Health and Human Services (HHS); specifies grantee, NIH, and
other HHS staff responsibilities and outlines the grant application and review
- Part II: Terms and Conditions of NIH Grant
Awards. Part II (chapters 3-19)
includes generally applicable terms and conditions (Part IIA). This part also
specifies the terms and conditions that apply to particular types of grants,
grantees, and activities that differ from, supplement, or elaborate on the
standard terms and conditions (Part IIB). These requirements, in separate
chapters, pertain to multiple PD/PI applications and awards; construction,
modernization and major alteration and renovation grants; research training
grants and fellowships; career development awards; modular applications and
awards; conference grants, consortium agreements;
grants to foreign and international organizations (and grants with substantial
foreign components awarded to domestic organizations), grants to Federal
institutions and payments to Federal employees; grants to for-profit
organizations; and research patient care activities.
- Part III: Points of Contact. Part III (chapter 20) lists pertinent
offices with their contact information.
Certain conventions are followed throughout this document.
The term "grant" is used to mean both grants and cooperative agreements;
however, for clarity, certain sections mention both grants and cooperative
agreements. The term "grantee" generally is used to refer to recipients of
grants and awardees of cooperative agreements; however the terms "recipient" or
"awardee" also are used. "NIH" may be used in this document to refer to the
entire organization or to its component organizations, or else to contrast an
action by NIH, including actions by its ICs, with an action by a grantee or
other organization. A reference to "Part II (IIA or IIB)" or "Part III" without
further elaboration means the corresponding part of the NIHGPS.
The NIHGPS was originally published with an effective date
of October 1, 1998. It was subsequently revised in 2001, 2003, and 2010. This revision
of the NIHGPS is an update of the 2010 publication. It applies to all NIH
grants and cooperative agreements for budget periods beginning on or after
October 1, 2011. While the update does not introduce any new material for the first time, it incorporates new and modified requirements,
clarifies certain policies, and implements changes in statutes,
regulations, and policies that have been implemented through appropriate legal and/or policy processes since the previous version of the GPS dated 10/1/2010. An explanation of the major changes to the NIHGPS since 10/1/2010 is included in the NIH Guide for
Grants and Contracts notice announcing the reissuance of the NIHGPS.
The Office of Policy for Extramural Research Administration
(OPERA) develops and maintains this document. Changes in statutes, regulations,
or policies that take effect before the next revision of the NIHGPS will be
published separately in the NIH Guide for Grants and
Contracts. Grantees are responsible for reviewing the NIH Guide for Grants and Contracts, which is published
on the NIH home page at https://grants.nih.gov/grants/guide/index.html,
for changes and for implementing them, as appropriate. Subscribe to the NIH Guide for Grants and Contracts Listserv at https://grants.nih.gov/grants/guide/listserv.htm.