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In order to create greater consistency in the administration of Federal research awards, all Federal research agencies now utilize a standard core set of administrative terms and conditions on research and research-related awards that are subject to 45 CFR Part 75, to the extent practicable. The core set of administrative requirements for participating Federal research agencies and other pertinent documents are posted at: http://www.nsf.gov/bfa/dias/policy/rtc/index.jsp. Recipients are encouraged to review the companion documents which include a Prior Approval Matrix, National Policy Requirement Matrix, Subaward Requirement Matrix, and Agency-Specific Requirements. NIH implementation of these Federalwide research terms and conditions has no significant change in the requirements or terms and conditions for NIH awardees.