Full Text TW-96-002 MINORITY INTERNATIONAL RESEARCH TRAINING GRANTS NIH GUIDE, Volume 25, Number 7, March 8, 1996 RFA: TW-96-002 P.T. 44, FF Keywords: Biomedical Research Training Biomedical Research, Multidiscipl Fogarty International Center Office of Research on Minority Health Application Receipt Date: May 7, 1996 PURPOSE The Fogarty International Center (FIC) and the Office of Research on Minority Health (ORMH) will support the development of training programs that offer international research training opportunities to qualified minorities (undergraduates, graduate students and faculty members) underrepresented in biomedical and behavioral research careers. Funds will be awarded to support innovative approaches to research training with a focus on (1) encouraging minority students to pursue post-baccalaureate degrees and consider research careers in the biomedical or behavioral sciences; (2) broadening minority student research training to include international issues and concerns; and (3) assisting the next generation of scientists to work effectively in the global environment by establishing international linkages on several levels--linkages between U.S. students and foreign scientists at centers of biomedical and behavioral research, between U.S. minority scientists and foreign scientists abroad, and between minority and minority-serving institutions and research institutions abroad. Applications may be submitted from individual U.S. institutions or from consortia of U.S. institutions with one lead institution. For the purposes of this program, consortia will link institutions that have active international programs with those with limited research and research training programs. This request for applications (RFA) is for the fourth funding cycle for this program. Both new and competing renewal applications are welcome. In the original announcement for this program the funding cycle was limited to three years, and only the participation of undergraduates and graduate students pursuing either the masters or doctoral degrees were encouraged. In this RFA the funding cycle has been extended to four years, a foreign mentor visitation component has been added, and the participation of medical students with a strong interest in pursuing biomedical or clinical research is encouraged. The support of Minority International Research Training (MIRT) Programs is consistent with the legislative mandate of the Fogarty International Center, which is to advance biomedical and public health related research and training through international cooperation. The program is also unique in its potential for ensuring diversity among the U.S. student population represented overseas, in particular, since minority students are less likely than their counterparts to participate in study abroad programs. HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2000", a PHS-led national activity for setting priority areas. This RFA, Minority International Research Training Program , is related to the priority of educational and community-based programs with a primary focus on special populations. Potential applicants may obtain a copy of Healthy People 2000" (Full Report: Stock No. 017-001-00474-0 or Summary Report: Stock No. 017-001-0473-1) through the Superintendent of Documents, Government Printing Office, Washington, DC 20402-9325, telephone 202/512-1800). ELIGIBILITY REQUIREMENTS The applicant institution and any associated institutions in a consortium must be at least two- or four-year domestic school, college or university. The foreign research site(s) should be a university, college or other research institution with strong, well established biomedical or behavioral research and research training programs. Close cooperation between U.S. and foreign scientists and their institutions is needed to provide participants with foreign mentors who will participate in their research training. Foreign mentors and research collaborators should be accomplished scientific investigators. Participating students and faculty must be members of groups underrepresented in careers in the biomedical sciences--African Americans, Hispanic Americans, American Indians and Alaskan natives and Asian/Pacific Islanders (i.e., American territories such as the Philippine Islands, Guam, Samoa etc.)--and be U.S. citizens or permanent residents who are pursuing degrees, studying and/or conducting research in the biomedical or behavioral sciences at the time of their appointment and during the program. Students and faculty must be affiliated with a U.S. college or university at the time of selection for the program; however, their affiliation need not be with the grantee institution. Undergraduate student trainees must be pre-baccalaureate, preferably those entering their junior and senior year (and in special cases sophomores), pursuing a curriculum in the life sciences and related areas and must show evidence of a commitment to obtaining a postgraduate research-related degree in the biomedical or behavioral sciences. Predoctoral students must be enrolled in a U.S. graduate research training program in the biomedical or behavioral sciences. Medical students, who are members of groups underrepresented in careers in biomedical/behavioral research and who have a strong interest in pursuing clinical or biomedical research, are eligible for participation. Faculty participants must have a regular, full-time faculty appointment at the grantee institution or an institution in the consortium. For acceptance in the program, a research plan which outlines the studies to be performed abroad including the expected benefits must be provided to and approved by the program director. In selected instances, with prior approval from the FIC, highly qualified medical residents or fellows may participate as faculty in the program. One person called the faculty mentor may accompany each group of approximately four to eight undergraduate students for the purpose of serving as a general advisor/mentor during the training period abroad. The faculty member must hold a full-time tenure track or tenured position at the grantee institution, hold a doctoral level degree, and have a biomedical research plan for studies to be conducted at the foreign host institution. If a minority faculty member is not available, any faculty member who meets the eligibility criteria for faculty mentor may serve in this position. MECHANISM OF SUPPORT The mechanism of support is the institutional training grant award (T37). Domestic institutions may request up to four years of support. The following also apply: o For undergraduates, graduate students, and medical students, stipends of up to $1,000 per month may be requested for the period at the foreign site; and for U.S. faculty participants, stipends of up to $3,000 per month are available. Stipends may be supplemented from non-Federal sources only; however, the stipend plus the home institution support for participating faculty cannot exceed the potential appointee s annual salary. o Funds to support student and faculty research activities at the foreign site may be requested at a maximum level of $600 per month per person. o Tuition, fees, insurance etc. (training related expenses for use at the foreign site) may be requested up to a maximum level of $500 per month for undergraduates, graduate students (medical students), and faculty participants. o Foreign living expenses of up to $1,000 per month for undergraduate and graduate students and up to $2,000 per month for faculty may be requested. o Economy class round-trip airfare on a U.S. carrier from home to the foreign training site plus local ground transportation at the foreign site may be requested. o For the foreign visitation component, foreign mentors (or their designees) may receive economy class round-trip airfare on a U.S. carrier plus a living allowance of up to $2,000 per month while in the U.S. In addition, foreign investigators visiting the U.S. for extended periods of time (at least one month) and who are not able to be maintained on salary from their home institution may be eligible for a stipend of up to $3,000 per month depending on their level of experience. Research related expenses of up to $600 per month may be requested. As a pilot to support research training in developing countries, supplements of up to $10,000 per year may be requested to support collaborative research projects at the foreign site, subject to peer review and prior FIC approval. (Only 4 to 5 such supplements will be made.) o If especially justified, the domestic applicant institution may request up to 10 percent of the requested total direct costs for the support of the principal investigator and/or other grant related personnel for domestic administrative efforts. These costs must be well justified and specifically related to this grant. Indirect costs will be awarded to the grantee institution at a rate of eight percent of the allowable direct costs. Please note that stipends, research-related training costs, and travel expenses are offered only for the time period that U.S. participants are en route to or working at the foreign site. Each of the training grant awards must not exceed a total of $400,000 per year, including direct and indirect costs. FUNDS AVAILABLE A total of $3,000,000 is available for this competition. It is expected that 10 to 15 new and/or competitive renewal awards will be made in FY 96. RESEARCH OBJECTIVES The Minority International Research Training grants are designed to offer research training opportunities to qualified students (undergraduates and pre-doctoral trainees) and faculty to participate in international biomedical and behavioral research programs abroad. The proposed training program is expected to increase student and faculty awareness of international research opportunities, to acquaint students with the full range of career opportunities in biomedical and behavioral research, and to encourage undergraduates to pursue post-baccalaureate research degrees. Faculty participants are expected to gain from the foreign research experience in ways that will contribute to the research and teaching programs at their U.S. institutions. Under these goals the following objectives have been identified: o To support research experiences for undergraduates in international laboratories under the mentorship of outstanding foreign scientists, o To support graduate student research training in areas that are particularly research relevant to their masters thesis or doctoral dissertation work, o To facilitate research collaborations between minority scientists and scientists at centers of biomedical research abroad. Additionally, the U.S. based foreign mentor provision is expected to: (1) be mutually beneficial to U.S. participants and their foreign mentors/collaborators in terms of facilitating collaborative research, (2) to benefit U.S. institutions with limited research capabilities, and/or (3) to provide additional research experiences for U.S. minority students and health scientists. SPECIAL REQUIREMENTS The program director at the applicant institution will be responsible for selecting and appointing student and faculty participants, selecting foreign training site(s), and directing the program. Except in the case of faculty mentors (see below), participating students and faculty must be members of groups underrepresented in careers in the biomedical sciences, which include, African Americans, Hispanic Americans, American Indians and Alaskan natives, and Asian/Pacific Islanders (i.e., American territories such as Guam, Samoa, etc.) and be U.S. citizens, non-citizen nationals, or permanent residents who are pursuing degrees, studying and/or conducting research in the biomedical or behavioral sciences at the time of their appointment and during the program. The FIC and ORMH staff will closely follow the progress of each training grant program through in-depth reviews of yearly progress reports, periodic meetings of program directors, and site visits. Training grants may include one or more of the following components: The Undergraduate Program This component will offer a biomedical research experience for minority students at research centers abroad where arrangements have been made to house and train the students for approximately 10 to 12 weeks at any appropriate time of the year. Training at the foreign site may include a short course in the language and culture of the host country; however, research training must be carried out during at least half of each weekday. Undergraduate research projects may include the collection of data, samples, or other information for research purposes. The projects may not include routine clinical or laboratory work without a research component. Each group of four to eight students may be accompanied by a faculty member who would also conduct research. This person is the Faculty Mentor--see below. Limited support may be available from the FIC for student attendance at scientific meetings to present the results of their foreign research. When needed, funds in the grant may also be rebudgeted to support student attendance at scientific meetings for the purpose of presenting their work. For exceptionally qualified students, research-related expenses (up to $500 per month) may be available (or rebudgeted in the grant) to facilitate the continuation of collaborative research projects and training after the students return to the U.S.--see U.S. based collaborative research below. Predoctoral Program The predoctoral component provides support for research training for minority predoctoral students at a foreign institution for periods of 3 to 12 months as a part of the requirement for (or as a research elective in) the doctoral degree (or master's degree) program in which the student is enrolled--support can only be received for the period that the student is abroad, however. Please note that the application must demonstrate the benefit of foreign training. The above also applies to medical students with an identified strong interest in pursuing biomedical or clinical research. Some course work may be included in the training plan; however, the period abroad must be primarily for the conduct of research, to learn a technique, to participant in a study or to utilize a resource or study population. Under special circumstances and with FIC staff approval, research-related expenses of up to $500 per month may be available (or rebudgeted) upon return to the U.S. institution for the continuation of collaborative research and training. Faculty Program The faculty component supports minority faculty members employed at U.S. colleges and universities to carry out collaborative, biomedically-related research abroad for periods of 3 to 12 months. The purpose of this component is to enhance faculty research through a foreign collaborative effort and/or to provide unique sites for undergraduate or graduate student training activities--the faculty member may accompany students in the undergraduate research program while also conducting research. To participate, the U.S. faculty member must have a doctoral-level degree or equivalent experience and training. Faculty participants are expected to conduct research on a biomedically related topic in collaboration with a foreign laboratory; their research plans should be submitted as an attachment to the yearly progress reports. In special cases, but only upon consultation with Fogarty staff, faculty participants may receive appointments of a minimum of 1 month to do collaborative research abroad, providing the following requirements are met: (1) the proposed collaborative research enhances and/or extends ongoing research in the potential participant's laboratory, (2) the faculty member has a research plan that can be completed in the limited time proposed, (3) the faculty member has active peer- reviewed research support. Faculty Mentor The role of the faculty mentor is to serve as a mentor/advisor to groups of four to eight minority undergraduate students during their time at the foreign research site. This involves assisting the students in adjusting to and coping with all phases of their research training and cultural experience while living abroad. Please note that the faculty mentor can only receive support from the training grant while he/she is with the students. Additionally, the faculty mentor must be involved in a research project while at the foreign site. If a faculty mentor will be an important part of the program and a minority faculty member is not available, a non-minority faculty member may fill this position. U.S.-Based Collaborative Research/Foreign Mentor Component The U.S.-based collaborative research component is designed to facilitate the research initiated at the foreign research training site with the approved mentor (or collaborator). To participate, the foreign scientist must meet the following requirements: (1) be an approved foreign mentor/collaborator or his/her designated representative, (2) hold a doctoral level degree or its equivalent, (3) have a full-time appointment at the foreign training site, (4) have a biomedical research plan that continues and/or extends the collaborative research that was either ongoing or initiated during the U.S. participants time at the foreign training site. INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS While the majority of support for training-related research may be derived from sources other than in this award, prospective awardees are expected to comply with NIH policy concerning study populations in the conduct of training-related research. It is the policy of the NIH that women and members of minority groups and their subpopulations must be included in all NIH supported biomedical and behavioral research projects involving human subjects, unless a clear and compelling rationale and justification is provided that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This new policy results from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43) and supersedes and strengthens the previous policies (Concerning the Inclusion of Women in Study Populations, and Concerning the Inclusion of Minorities in Study Populations), which have been in effect since 1990. The new policy contains some provisions that are substantially different from the 1990 policies. All investigators proposing research involving human subjects should read the NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research, which have been published in the Federal Register of March 28, 1994 (59 FR 14508-14513) and printed in the NIH Guide for Grants and Contracts, Volume 23, Number 11, March 18, 1994. Investigators may also obtain copies of the policy from the program staff listed under INQUIRIES. Program Staff may also provide additional relevant information concerning the policy. Assurances While, in most cases, the primary support for training-related research and associated assurances of protection for human subjects and/or animals, will be covered through other funding mechanisms, the program directors are responsible to assure that all training-related research supported under this program meets applicable NIH requirements. Applicant institutions are reminded that adequate protection for human subjects and animals at the foreign training site is an essential requirement by the NIH. Awardee institutions and each performance site must agree that the rights and welfare of human subjects and animals involved in research under this award shall be protected in accordance with 45 CFR 46. As a condition of award, not as a condition of application, applicants and affiliated performance sites are required to possess an applicable assurance of compliance that has been approved by the Office for Protection from Research Risks (OPRR) of the NIH. Applicants will receive specific information for obtaining foreign assurances following the initial review of the application. APPLICATION PROCEDURES Applications are to be submitted on the public health service grant application form PHS 398 (rev. 5/95) using the special instructions related to Institutional National Research Service Awards (Section VII). Note the requirement to use NRSA substitute pages MM, NN, OO to be acceptable for initial review. Applications kits are available at most institutional offices of sponsored research and may be obtained from the Grants Information Office, Office of Extramural Outreach and Information Resources, National Institutes of Health, 6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone 301/710-0267, email: girg@drgpo.drg.nih.gov. The RFA label available in the PHS 398 (rev. 5/95) application form must be affixed to the bottom of the face page of the application. Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. In addition, the RFA title and number must be typed on line 2 of the face page of the application form and the YES box must be marked. The completed application and three legible copies must be sent or delivered to the following address and received by May 7, 1996: DIVISION OF RESEARCH GRANTS NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE, MSC 7710 BETHESDA, MD 20892-7710 BETHESDA, MD 20817 (for overnight courier delivery) In addition, two copies of the completed application must be sent to Dr. Flagg-Newton at the address listed under INQUIRIES. REVIEW CONSIDERATIONS All applications responding to this RFA will be reviewed for scientific and technical merit by an NIH initial review group, followed by a second level review by the Fogarty International Center Advisory Board. To be eligible for review, applications must be complete and submitted in accordance with the application procedures stated above. Letters from the foreign collaborators and their institutional officials indicating their willingness to participate in this training program must accompany the application. The following criteria apply to new applicant institutions as well as those seeking a competitive renewal. Factors to be considered in the scientific evaluation of each application include: o Adequacy of methods and criteria for selecting student and faculty participants, o Justification for selecting the proposed foreign sites including the availability of adequate facilities and general environment for the conduct of the proposed research training, o Adequacy of the qualifications (including level of education and training) and relevant research experience of the principal investigator, key personnel, and the ability of the foreign mentor/collaborator to undertake and direct the foreign research activities of the project, o Appropriateness of budget estimates and appropriateness and duration of the proposed research training experiences for students, The following also apply for applications for competitive renewal. o Progress and accomplishments including student educational outcomes and research productivity (i.e, presentations at scientific meetings, coauthored, peer reviewed publications) and faculty participant productivity (i.e, peer reviewed publications, abstracts, applications for research support.) AWARD CRITERIA Applications will compete for funds assigned to the Minority International Research Training Grant Program of the Fogarty International Center and the Office of Research on Minority Health. The following will be considered in making funding decisions: scientific, technical and educational merit of the application as determined by peer review; likelihood that the proposal will contribute to the achievement of the program's objectives, and availability of funds. INQUIRIES Inquiries concerning this RFA are encouraged. The opportunity to clarify any issues or questions from potential applicants is welcomed. Inquiries regarding programmatic issues and two copies of the application form may be directed to: Dr. Jean L. Flagg-Newton Division of International Training and Research Fogarty International Center Building 31, Room B2C39 - MSC 2220 Bethesda, MD 20892-2220 Telephone: (301) 496-1653 FAX: (301) 402-0779 Email: flaggnej@ficod.fic.nih.gov Direct inquiries regarding fiscal matters to: Ms. Silvia Mandes Division of International Training and Research Fogarty International Center Building 31, Room B2C39 - MSC 2220 Bethesda, MD 20892-2220 Telephone: (301) 496-1653 FAX: (301) 402-0779 Email: mandess@ficod.fic.nih.gov AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance No. 93.106. Awards are made under the authority of the Public Health Service Act, Title III, Part A, Section 307b (42 USC 2421) and administered under PHS grants policies and Federal regulations, most specifically 42 CFR Part 61. This program is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. The PHS strongly encourages all grant and contract recipients to provide a smoke-free workplace and promote the non-use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people. .
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