CORE IMMUNOLOGY LABORATORY FOR ASSESSMENT OF AIDS VACCINES INPRIMATES NIH GUIDE, Volume 21, Number 37, October 16, 1992 RFP: NIH-NIAID-DAIDS-93-15 P.T. 34 Keywords: AIDS Vaccine Immunology Bioassay National Institute of Allergy and Infectious Diseases The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) has a requirement to provide for the centralized performance of immunological assays to support preclinical AIDS vaccine trials in primates. The purpose of this contract is to support the NIAID in its mission to stimulate research towards discovery and testing of prototype vaccines for the acquired immunodeficiency syndrome (AIDS). The NIAID requires a Primate Core Immunology Laboratory to assay specimens from macaques, chimpanzees, or other primates for humoral and cellular immune responses induced by immunization with prototype Simian Immunodeficiency Virus (SIV) and Human Immunodeficiency Virus (HIV) vaccines. This effort will support the research of AIDS investigators, including three SIV Vaccine Evaluation Units (SIV VEU), a Chimpanzee Unit, the National Cooperative Vaccine Evaluation Group (NCVDG), the AIDS Vaccine Evaluation Group (AVEG), and other programs initiated by NIAID. Specifically, the selected contractor will be responsible for: (1) performing specific evaluations of cellular immune responses induced by vaccination; (2) performing specific evaluations of humoral immune responses induced by vaccination; (3) adapting, standardizing, providing quality assurance, and performing any newly developed immunological assays that may be identified during the period of the contract as offering potential for assessment of vaccine safety and immunogenicity; (4) receiving, cataloging, tracking, and maintaining an inventory of the specimens arriving for evaluation; and (5) maintaining test result database and transferring data to the AIDS Vaccine Clinical Trials Network (AVCTN) Data Coordinating and Analysis Center (DCAC). This is an announcement for an anticipated Request for Proposals (RFP). The issuance of RFP NIH-NIAID-DAIDS-93-15 will be on or about October 16, 1992, and proposals will be due by the close-of-business on January 5, 1993. It is anticipated that one contract will be awarded as a result of this solicitation and that the contract will have a five-year period of performance. A completion type cost-reimbursement contract is anticipated. Requests for the RFP must be directed in writing to -- Kristi Hofacker, Contract Specialist Contract Management Branch National Institute of Allergy and Infectious Diseases Solar Building, Room 3C07 6003 Executive Boulevard Bethesda, MD 20892 Provide this office with three self-addressed mailing labels. Telephone inquiries will not be honored and all inquiries must be in writing. A short-form version of the RFP will be provided first. That version includes only the Statement of Work and the Evaluation Criteria to be used for selection of the awardee. After examining this document, a full-text version of the RFP must be requested, in writing, for those offerors interested in responding. FAX requests are acceptable for full-text versions of the RFP only (FAX: 301-402-0972). All proposals from responsible sources will be considered by the NIAID. This advertisement does not commit the Government to award a contract. .
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