and Human Services (HHS)
EXPIRED
Participating Organization(s) |
National Institutes of Health (NIH) |
National Institute of Mental Health (NIMH) |
|
Funding Opportunity Title |
Harnessing Advanced Health Technologies to Drive Mental Health Improvement (R34) |
Activity Code |
R34 Clinical Trial Planning Grant Program |
Announcement Type |
New |
Related Notices |
None |
Funding Opportunity Announcement (FOA) Number |
RFA-MH-13-061 |
Companion Funding Opportunity |
RFA-MH-13-060, R01 Research Project Grant |
Catalog of Federal Domestic Assistance (CFDA) Number(s) |
93.242 |
Funding Opportunity Purpose |
The purpose of this Funding Opportunity Announcement (FOA) is to test the innovative use of existing technologies to significantly improve access to and quality of mental health care, and to propose the collection and use of actionable mental health information to improve outcomes of people with mental disorders. |
Posted Date |
March 2, 2012 |
Open Date (Earliest Submission Date) |
May 22, 2012 |
Letter of Intent Due Date |
May 22, 2012 |
Application Due Date(s) |
June 22, 2012, by 5:00 PM local time of applicant organization. |
AIDS Application Due Date(s) |
Not Applicable |
Scientific Merit Review |
October 2012 |
Advisory Council Review |
January 2013 |
Earliest Start Date(s) |
April 1, 2013 |
Expiration Date |
June 23, 2012 |
Due Dates for E.O. 12372 |
Not Applicable |
Required Application Instructions
It is critical that applicants follow the instructions in the SF 424 (R&R) Application Guide, except where instructed to do otherwise (in this FOA or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced. Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.
Part 1. Overview Information
Part 2. Full Text of the Announcement
Section I. Funding Opportunity Description
Section II. Award Information
Section III. Eligibility Information
Section IV. Application and Submission
Information
Section V. Application Review Information
Section VI. Award Administration Information
Section VII. Agency Contacts
Section VIII. Other Information
For decades, difficulties in accessing high-quality mental health services were a direct function of the limitations of resources, geographical inequities and lack of available information to appropriately assess, treat, and monitor illness. The bricks and mortar mental health care setting is a clearly identified site of care, but with finite capacity due to fixed hours and a set level of staff. In addition, assessment of illness has most frequently been done through clinical visits, using a series of established tools, but gaining only retrospective data (e.g. , Personal Health Questionnaire-9: over the past two weeks, how often have you been bothered by the following problems? ) or requiring direct clinical observation. In the past decade, the technological revolution has dramatically changed the way in which we communicate, seek information and receive services. Technologies currently in the pockets of millions have the potential to dramatically improve upon the traditional care delivery system.
Within mental health services and intervention research, there is tremendous interest in the use of health information technology to transport health care into the information age, but a disconnect frequently lies in the relative lack of exposure and expertise of mental health researchers to emergent technologies. Too many studies seek to apply the same technologies (e.g., web, telephone) to traditional face-to-face interventions, attempting to find equivalence with technology-based delivery. While there remains value in the transportation of these interventions onto technological platforms, there is an entire set of newer technologies that could have dramatic impact on access, quality, and delivery of care, and have been understudied and rarely applied to mental health. This initiative seeks high risk, high reward investigations that apply novel technologies to improve access to, and quality and delivery of mental health services.
A 2010 workshop, co-run by NIMH and the Agency for Healthcare Research and Quality, Mental Health & Health IT Research: The Way Forward, brought together experts in mental health interventions and services research with technologists, providers, consumers, and industry representatives to discuss opportunities to leverage emerging technologies toward improved research and service delivery. Participants identified a number of significant gaps in our knowledge, which were cross-walked with ongoing analysis of the relevant NIMH portfolio. Discussions anchored around four key areas: 1) the ability to impact access to mental health treatment; 2) the need for improved measurement and data capture for mental health research, 3) the tailoring of interventions to fit the specifications and advantages of technological platforms, and 4) methods through which mental health information could be integrated within electronic health records. The workshop discussions established the viability and the need to use health technologies to transform the experience of mental health care, from a traditional system to one of no bounds.
Example research questions considered responsive to the goals of the FOA include, but are not limited to, the following:
Priority will be given to applications that propose novel applications of technology that could potentially generalize across indications and target populations as well as multiple operating systems. Applications that propose to adapt or replicate proven/existing technologies for use with additional mental disorders or target populations will be considered less competitive. Prospective applicants are encouraged to contact program staff for additional guidance on research topics.
This FOA encourages applications that place a premium on two key features: Innovation and Impact. Innovation, in this context, refers to technological solutions that have not been applied to the mental health service continuum (screening, assessment, intervention, referral, monitoring). Impact, for this announcement, refers to a demonstrable benefit of the technological application on access, quality, costs, or outcomes of care.
Although NIMH sees the value of non-inferiority trials to show the ability of new platforms to competently substitute for traditional care pathways, this FOA strongly recommends designs targeting clinically and functionally significant benefits over existing care delivery systems.
In addition, given the emphasis on innovation, applications will likely require teams of researchers, system leaders, and technology experts in order to ensure that the proposed technologies are current, feasible, and compatible with use in mental health service systems. Wherever possible, applications are encouraged to utilize efficient research approaches, including leveraging existing platforms for subject recruitment, data collection, and analysis.
R34 Specific Information
The sections on pilot testing for effectiveness and on innovative services research found in PAR-09-173 can serve as a useful guideline for the development of such studies under this announcement. The R34 should propose the developmental work to be performed that would enhance the probability of success in a larger study. Designs need not be reduced scope versions of the anticipated larger study, but should instead attempt to develop and refine the research strategies to be utilized in the subsequent definitive study. NIMH recognizes that while the scope of interest for this FOA is consistent across both R34 and R01 announcements, there are specific research topics for which the field may not yet be ready for a definitive trial. The R34 provides the opportunity for high risk, high reward studies and these will be of high priority to the NIMH.
Thus, appropriate research activities for the R34 might include: refining and pilot testing the technologies hypothesized to significantly impact mental health care and associated outcomes; working out the details of the study protocols and randomization procedures (if appropriate); examining the feasibility of recruiting and retaining participants into the study conditions; and/or developing supportive materials and resources. In addition, collection of preliminary data regarding feasibility, acceptability, safety, tolerability, and target outcomes are also appropriate. Given the intended pilot nature of the R34 mechanism, conducting a formal test of outcomes is not required and obtaining an estimate of an effect size may not be possible.
References
Merikangas, KR, He, JP, Burstein, M, Swanson, SA, Avenevoli, S, Case, B, Georgiades, K, Heaton, L, Swanson, S, Olfson, M. (2011) Service utilization for lifetime mental disorders in U.S. adolescents: results of the National Comorbidity Survey-Adolescent Supplement (NCS-A). Journal of the American Academy of Child and Adolescent Psychiatry. 50(1): 32-45.
Wang, PS, Lane, M, Olfson, M, Pincus, H, Wells, KB, & Kessler, RC. (2005). Twelve-month use of mental health services in the United States. Archives of General Psychiatry. 62(6): 629-40.
Funding Instrument |
Grant |
Application Types Allowed |
New The OER Glossary and the SF 424 (R&R) Application Guide provide details on these application types. |
Funds Available and Anticipated Number of Awards |
The NIMH intends to commit approximately $3,000,000 in FY 2013 to fund between 6-8 grants in response to this FOA and the companion announcement. |
Award Budget |
Direct costs are limited to $450,000 over the R34 3-year project period, with no more than $225,000 in direct costs allowed in any single year. |
Award Project Period |
The total project period for an application submitted in response to this FOA may not exceed 3 years. |
NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made in response to this FOA.
Higher Education Institutions
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
Nonprofits Other Than Institutions of Higher Education
For-Profit Organizations
Governments
Other
Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Applicant organizations must complete the following registrations
as described in the SF 424 (R&R) Application Guide to be eligible to apply
for or receive an award. Applicants must have a valid Dun and Bradstreet
Universal Numbering System (DUNS) number in order to begin each of the following
registrations.
All Program Director(s)/Principal Investigator(s) (PD(s)/PI(s))
must also work with their institutional officials to register with the eRA
Commons or ensure their existing eRA Commons account is affiliated with the eRA
Commons account of the applicant organization.
All registrations must be completed by the application due date. Applicant
organizations are strongly encouraged to start the registration process at
least 4-6 weeks prior to the application due date.
Any individual(s) with the skills, knowledge, and resources
necessary to carry out the proposed research as the Program Director(s)/Principal
Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to
develop an application for support. Individuals from underrepresented racial
and ethnic groups as well as individuals with disabilities are always
encouraged to apply for NIH support.
For institutions/organizations proposing multiple PD(s)/PI(s), visit the Multiple
Program Director(s)/Principal Investigator(s) Policy and submission details in
the Senior/Key Person Profile (Expanded) Component of the SF 424 (R&R)
Application Guide.
This FOA does not require cost sharing as defined in the NIH Grants Policy Statement.
Applicant organizations may submit more than one application, provided that each application is scientifically distinct.
NIH will not accept any application in response to this FOA that is essentially the same as one currently pending initial peer review unless the applicant withdraws the pending application. NIH will not accept any application that is essentially the same as one already reviewed. .
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the Apply for Grant Electronically button in this FOA or following the directions provided at Grants.gov.
It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide, except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
For information on Application Submission and Receipt, visit Frequently Asked Questions Application Guide, Electronic Submission of Grant Applications.
Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review.
By the date listed in Part 1. Overview Information, prospective applicants are asked to submit a letter of intent that includes the following information:
The letter of intent should be sent to:
David Chambers, D.Phil
Division of Services and Intervention Research
National Institute of Mental Health
6001 Executive Boulevard, Room 7164, MSC 9631
Bethesda, MD 20892-9631
Rockville, MD 20852 (for express/courier service)
Telephone: 301-443-3747
Email: [email protected]
The forms package associated with this FOA includes all applicable components, mandatory and optional. Please note that some components marked optional in the application package are required for submission of applications for this FOA. Follow all instructions in the SF424 (R&R) Application Guide to ensure you complete all appropriate optional components.
All page limitations described in the SF424 Application Guide and the Table of Page Limits must be followed.
All instructions in the SF424 (R&R) Application Guide must be followed, with the following additional instructions:
Resource Sharing Plan
Individuals are required to comply with the instructions for the Resource Sharing Plans (Data Sharing Plan, Sharing Model Organisms, and Genome Wide Association Studies(GWAS)) as provided in the SF424 (R&R) Application Guide.
Appendix
Do not use the Appendix to circumvent page limits. Follow all instructions for the Appendix as described in the SF424 (R&R) Application Guide.
Foreign (non-US) institutions must follow policies described in the NIH Grants Policy Statement, and procedures for foreign institutions described throughout the SF424 (R&R) Application Guide.
Part I. Overview Information contains information about Key Dates. Applicants are encouraged to submit in advance of the deadline to ensure they have time to make any application corrections that might be necessary for successful submission.
Organizations must submit applications via Grants.gov, the online portal to find and apply for grants across all Federal agencies. Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH’s electronic system for grants administration.
Applicants are responsible for viewing their application in the eRA Commons to ensure accurate and successful submission.
Information on the submission process and a definition of on-time submission are provided in the SF424 (R&R) Application Guide.
This initiative is not subject to intergovernmental review.
All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.
Pre-award costs are allowable only as described in the NIH Grants Policy Statement.
Applications must be submitted electronically following the instructions described in the SF 424 (R&R) Application Guide. Paper applications will not be accepted.
Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.
For assistance with your electronic application or for more information on the electronic submission process, visit Applying Electronically.
Important
reminders:
All PD(s)/PI(s) must include their eRA Commons ID in the
Credential field of the Senior/Key Person Profile Component of the SF
424(R&R) Application Package. Failure to register in the Commons and
to include a valid PD/PI Commons ID in the credential field will prevent the
successful submission of an electronic application to NIH.
The applicant organization must ensure that the DUNS number it provides on the
application is the same number used in the organization’s profile in the eRA
Commons and for the Central Contractor Registration (CCR). Additional
information may be found in the SF424 (R&R) Application Guide.
See more
tips for avoiding common errors.
Upon receipt, applications will be evaluated for completeness by the Center for Scientific Review and responsiveness by NIMH. Applications that are incomplete and/or nonresponsive will not be reviewed.
In order to expedite review, applicants are requested to notify the NIMH Referral Office by email at [email protected] when the application has been submitted. Please include the FOA number and title, PD/PI name, and title of the application.
Applicants are required to follow the instructions for post-submission materials, as described in NOT-OD-10-115.
Only the review criteria described below will be considered in the review process. As part of the NIH mission, all applications submitted to the NIH in support of biomedical and behavioral research are evaluated for scientific and technical merit through the NIH peer review system.
The NIMH R34 clinical exploratory/developmental grant is a mechanism for supporting the development and/or pilot testing of new or adapted interventions, pilot testing of interventions with demonstrated efficacy in broader scale effectiveness trials, or conducting pilot innovative services research that requires preliminary testing or development. Because this is a clinical exploratory/developmental grant application, it need not have extensive background material or preliminary information as one might normally expect in an R01 application. Accordingly, reviewers will focus their evaluation on the conceptual framework, the level of innovation, and the potential to significantly advance our knowledge or understanding. Reviewers will be instructed to place less emphasis on methodological details and certain indicators traditionally used in evaluating the scientific merit of R01 applications, including supportive preliminary data. Appropriate justification for the proposed work can be provided through literature citations, data from other sources, or, when available, from investigator-generated data. Preliminary data are not required for R34 applications, but may be included if available.
As described in Part 2, Section I, impact, for this announcement, refers to a demonstrable benefit of the technological application on access, quality, costs, or outcomes of care. Reviewers will provide an overall impact/priority score to reflect their assessment of the likelihood for the project to exert a sustained, powerful influence on the research field(s) involved, given the emphasis of the FOA, in consideration of the following review criteria and additional review criteria (as applicable for the project proposed).
Reviewers will consider each of the review criteria below in the determination of scientific merit, and give a separate score for each. An application does not need to be strong in all categories to be judged likely to have major scientific impact. For example, a project that by its nature is not innovative may be essential to advance a field
Significance
Does the project address an important problem or a critical barrier to progress in the field? If the aims of the project are achieved, how will scientific knowledge, technical capability, and/or clinical practice be improved? How will successful completion of the aims change the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field? Is the technology used relevant and/or adaptable to future operating systems following the completion of the study? Does the application propose novel uses of technology that could potentially generalize across indications and target populations? Does the application propose designs targeting clinically and functionally significant benefits over existing care delivery systems? If successful, is the technological application likely to result in a demonstrable benefit on access, quality, costs, or outcome of care?
Investigator(s)
Are the PD(s)/PI(s), collaborators, and other researchers well suited to the project? If Early Stage Investigators or New Investigators, or in the early stages of independent careers, do they have appropriate experience and training? If established, have they demonstrated an ongoing record of accomplishments that have advanced their field(s)? If the project is collaborative or multi-PD(s)/PI(s), do the investigators have complementary and integrated expertise; are their leadership approach, governance and organizational structure appropriate for the project? Does the team have sufficient expertise in mental health interventions and services and technologies?
Innovation
Does the application challenge and seek to shift current research or clinical practice paradigms by utilizing novel theoretical concepts, approaches or methodologies, instrumentation, or interventions? Are the concepts, approaches or methodologies, instrumentation, or interventions novel to one field of research or novel in a broad sense? Is a refinement, improvement, or new application of theoretical concepts, approaches or methodologies, instrumentation, or interventions proposed? Does the application propose technological solutions that have not been applied to the mental health service continuum (screening, assessment, intervention, referral, monitoring?
Approach
Are the overall strategy, methodology, and analyses
well-reasoned and appropriate to accomplish the specific aims of the project?
Are potential problems, alternative strategies, and benchmarks for success
presented? If the project is in the early stages of development, will the
strategy establish feasibility and will particularly risky aspects be managed? Will the project leverage existing research networks and infrastructure (where
appropriate) to enable rapid participant recruitment and data analysis? Will
the project use novel and efficient study designs? If the approach(es) entail
a high degree of risk how do the potential benefits/rewards outweigh the risks?
If the project involves clinical research, are the plans for 1) protection of
human subjects from research risks, and 2) inclusion of minorities and members
of both sexes/genders, as well as the inclusion of children, justified in terms
of the scientific goals and research strategy proposed?
Environment
Will the scientific environment in which the work will be done contribute to the probability of success? Are the institutional support, equipment and other physical resources available to the investigators adequate for the project proposed? Will the project benefit from unique features of the scientific environment, subject populations, or collaborative arrangements?
As applicable for the project proposed, reviewers will evaluate the following additional items while determining scientific and technical merit, and in providing an overall impact/priority score, but will not give separate scores for these items.
Protections for Human Subjects
For research that involves human subjects but does
not involve one of the six categories of research that are exempt under 45 CFR
Part 46, the committee will evaluate the justification for involvement of human
subjects and the proposed protections from research risk relating to their
participation according to the following five review criteria: 1) risk to
subjects, 2) adequacy of protection against risks, 3) potential benefits to the
subjects and others, 4) importance of the knowledge to be gained, and 5) data
and safety monitoring for clinical trials.
For research that involves human subjects and meets the criteria for one or
more of the six categories of research that are exempt under 45 CFR Part 46,
the committee will evaluate: 1) the justification for the exemption, 2) human
subjects involvement and characteristics, and 3) sources of materials. For
additional information on review of the Human Subjects section, please refer to
the Human
Subjects Protection and Inclusion Guidelines.
Inclusion of Women, Minorities, and Children
When the proposed project involves clinical research, the committee will evaluate the proposed plans for inclusion of minorities and members of both genders, as well as the inclusion of children. For additional information on review of the Inclusion section, please refer to the Human Subjects Protection and Inclusion Guidelines.
Vertebrate Animals
Not Applicable.
Biohazards
Reviewers will assess whether materials or procedures proposed are potentially hazardous to research personnel and/or the environment, and if needed, determine whether adequate protection is proposed.
Resubmissions
Not Applicable.
Renewals
Not Applicable.
Revisions
Not Applicable.
As applicable for the project proposed, reviewers will consider each of the following items, but will not give scores for these items, and should not consider them in providing an overall impact/priority score.
Applications from Foreign Organizations
Reviewers will assess whether the project presents special opportunities for furthering research programs through the use of unusual talent, resources, populations, or environmental conditions that exist in other countries and either are not readily available in the United States or augment existing U.S. resources.
Select Agent Research
Reviewers will assess the information provided in this section of the application, including 1) the Select Agent(s) to be used in the proposed research, 2) the registration status of all entities where Select Agent(s) will be used, 3) the procedures that will be used to monitor possession use and transfer of Select Agent(s), and 4) plans for appropriate biosafety, biocontainment, and security of the Select Agent(s).
Resource Sharing Plans
Reviewers will comment on whether the following Resource Sharing Plans, or the rationale for not sharing the following types of resources, are reasonable: 1) Data Sharing Plan; 2) Sharing Model Organisms; and 3) Genome Wide Association Studies (GWAS).
Budget and Period of Support
Reviewers will consider whether the budget and the requested period of support are fully justified and reasonable in relation to the proposed research.
Applications will be evaluated for scientific and technical merit by (an) appropriate Scientific Review Group(s), convened by the NIMH,, in accordance with NIH peer review policy and procedures, using the stated review criteria. Review assignments will be shown in the eRA Commons.
As part of the scientific peer review, all applications:
Appeals of initial peer review will not be accepted for applications submitted in response to this FOA.
Applications will compete for available funds with all other recommended applications submitted in response to this FOA. Following initial peer review, recommended applications will receive a second level of review by the National Advisory Mental Health Council. The following will be considered in making funding decisions:
After the peer review of the application is completed, the PD(s)/PI(s) will be able to access his or her Summary Statement (written critique) via the eRA Commons.
Information regarding the disposition of applications is available in the NIH Grants Policy Statement.
If the application is under consideration for funding, NIH
will request "just-in-time" information from the applicant as
described in the NIH
Grants Policy Statement.
A formal notification in the form of a Notice of Award (NoA) will be provided
to the applicant organization for successful applications. The NoA signed by
the grants management officer is the authorizing document and will be sent via
email to the grantee’s business official.
Awardees must comply with any funding restrictions described in Section IV.5. Funding Restrictions. Selection
of an application for award is not an authorization to begin performance. Any
costs incurred before receipt of the NoA are at the recipient's risk. These
costs may be reimbursed only to the extent considered allowable pre-award costs.
Any application awarded in response to this FOA will be subject to the DUNS,
CCR Registration, and Transparency Act requirements as noted on the Award
Conditions and Information for NIH Grants website.
All NIH grant and cooperative agreement awards include the NIH Grants Policy Statement as part of the NoA. For these terms of award, see the NIH Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards, Subpart A: General and Part II: Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions for Specific Types of Grants, Grantees, and Activities. More information is provided at Award Conditions and Information for NIH Grants.
Cooperative Agreement Terms and Conditions of Award
Not Applicable.
When multiple years are involved, awardees will be required to submit the Non-Competing Continuation Grant Progress Report (PHS 2590) annually and financial statements as required in the NIH Grants Policy Statement.
A final progress report, invention statement, and the expenditure data portion of the Federal Financial Report are required for closeout of an award, as described in the NIH Grants Policy Statement.
The Federal Funding Accountability and Transparency Act of 2006 (Transparency Act), includes a requirement for awardees of Federal grants to report information about first-tier subawards and executive compensation under Federal assistance awards issued in FY2011 or later. All awardees of applicable NIH grants and cooperative agreements are required to report to the Federal Subaward Reporting System (FSRS) available at www.fsrs.gov on all subawards over $25,000. See the NIH Grants Policy Statement for additional information on this reporting requirement.
We encourage inquiries concerning this funding opportunity
and welcome the opportunity to answer questions from potential applicants.
Grants.gov
Customer Support (Questions regarding Grants.gov registration and
submission, downloading or navigating forms)
Contact Center Phone: 800-518-4726
Email: [email protected]
GrantsInfo (Questions regarding application instructions and
process, finding NIH grant resources)
Telephone 301-710-0267
TTY 301-451-5936
Email: [email protected]
eRA Commons Help Desk (Questions regarding eRA Commons
registration, tracking application status, post submission issues)
Phone: 301-402-7469 or 866-504-9552 (Toll Free)
TTY: 301-451-5939
Email: [email protected]
David Chambers, D.Phil
Division of Services and Intervention Research
National Institute of Mental Health
6001 Executive Blvd, Room 7164
Bethesda, MD 20892-9631
Rockville, MD 20852 (for express/courier service)
Telephone: 301-443-3747
Email: [email protected]
David Armstrong, Ph.D.
Division of Extramural Activities
National Institute of Mental Health
6001 Executive Boulevard, Room 6138, MSC 9606
Bethesda, MD 20892-9606
Telephone: (301) 443-3534
Email: [email protected]
Rebecca Claycamp, M.S., CRA
National Institute of Mental Health (NIMH)
Telephone: (301) 443-2811
Email: [email protected]
Recently issued trans-NIH policy notices may affect your application submission. A full list of policy notices published by NIH is provided in the NIH Guide for Grants and Contracts. All awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.
Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 45 CFR Parts 74 and 92.
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