Part I Overview Information

Department of Health and Human Services

Participating Organizations
Office of Public Health Research (OPHR/CDC), at

Components of Participating Organizations
Office of Public Health Research, (OPHR) Centers for Disease Control and Prevention (OPHR/CDC), at

Title: CDC Public Health Research: Health Protection Research Initiative


The CDC policies, guidelines, terms, and conditions stated in this announcement may differ from those used by the NIH

Authority: Section 317(k)(2) of the Public Health Service Act, 42 U.S.C. 247b(k)(2), as amended.

Announcement Type:
Competitive Continuation

Request For Applications (RFA) Number: RFA-CD-07-001

Catalog of Federal Domestic Assistance Number(s):
Innovations in Applied Public Health Research

Key Dates
Release Date: June 6, 2006
Letter of Intent Receipt Date: Not required
Application Receipt Date(s): July 28, 2006
Peer Review Date: September, 2006
Council Review Date: September, 2006
Earliest Anticipated Start Date: September 30, 2007
Additional Information To Be Available Date (URL Activation Date): NA
Expiration Date: July 29, 2006

Due Date for E.O. 12372
Executive Order 12372 does not apply to this program.

Additional Overview Content

Executive Summary

Table of Contents

Part I Overview Information

Part II Full Text of Announcement

Section I. Funding Opportunity Description
1. Research Objectives

Section II. Award Information
1. Mechanism(s) of Support
2. Funds Available

Section III. Eligibility Information
1. Eligible Applicants
    A. Eligible Institutions
    B. Eligible Individuals
2.Cost Sharing or Matching
3.Other - Special Eligibility Criteria

Section IV. Application and Submission Information
1. Address to Request Application Information
2. Content and Form of Application Submission
3. Submission Dates and Times
    A. Receipt and Review and Anticipated Start Dates
       1. Letter of Intent
    B. Sending an Application
    C. Application Processing
4. Intergovernmental Review
5. Funding Restrictions
6. Other Submission Requirements

Section V. Application Review Information
1. Criteria
2. Review and Selection Process
    A. Additional Review Criteria
    B. Additional Review Considerations
    C. Sharing Research Data
    D. Sharing Research Resources
3. Anticipated Announcement and Award Dates

Section VI. Award Administration Information
1. Award Notices
2. Administrative and National Policy Requirements  
    A. Cooperative Agreement Terms and Conditions of Award
       1. Principal Investigator Rights and Responsibilities
       2. CDC Responsibilities
       3. Collaborative Responsibilities
3. Reporting

Section VII. Agency Contact(s)
1. Scientific/Research Contact(s)
2. Peer Review Contact(s)
3. Financial/ Grants Management Contact(s)
4. General Questions Contact(s)

Section VIII. Other Information - Required Federal Citations

Part II - Full Text of Announcement

Section I. Funding Opportunity Description

1. Research Objectives

The CDC and OPHR are committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010" and to measuring program performance as stipulated by the Government Performance and Review Act (GPRA).  This RFA addresses “Healthy People 2010” priority area(s) of Health Professional Training and is in alignment with CDC’s performance goal(s) to increase the number of frontline public health workers at the State and local level that are competent and prepared to respond to bioterrorism, other infectious disease outbreaks, and other public health threats and emergencies and prepare frontline State and local health departments and laboratories to respond to current and emerging public health threats. For more information, see and  The authorizing statute for this RFA is section 317(k)(2) of the Public Health Service Act, 42 U.S.C. 247b(k)(2), as amended.

The purpose of this program is to continue existing Graduate Training Program grants (T01) that are focused on health protection and support Master’s and Doctoral level training. Health protection should be interpreted to include activities that 1) promote health and/or prevent disease, injury, or disability or 2) protect people from health threats including infectious, environmental, and terrorist threats. 

Training Programs

The T01 grants, also known as Graduate Training Program (GTP) grants, described in this announcement provide support to training programs at institutions of higher education.  GTP grants are designed to allow the director of the graduate program to select the scholars and to develop a curriculum of study and research experiences necessary to provide high quality public health research training.  Training programs that allow support for study opportunities from complementary disciplines and/or stimulate other relevant interdisciplinary training within the institution are encouraged.  In order to maximize the unique strengths and capabilities of institutions, consideration will be given to the development of new and innovative academic component programs that are relevant to the field of public health research.

In conducting activities to achieve the purpose of this program, the awardee institution will be responsible for the following activities that define the programs to be conducted:

Individuals will be trained in team research settings.  Programs will include didactic and practical training in various aspects of the design, conduct, and analysis of public health research with the goal of advancing public health research in complex areas of health protection research and promoting the conduct of research in highly collaborative settings.  Programs must develop and propose a core didactic curriculum that will be presented to all first year public health scholars. Programs are encouraged to provide Doctoral and Master trainees instruction in the following areas:

The first year of each scholar’s program should be dedicated primarily to core curriculum that must include a multi-disciplinary aspect to foster interaction among scholars and faculty from various disciplines.  The curriculum should link to other available research training programs at the institution.  The program must demonstrate the flexibility to accommodate multiple disciplines and scholars with different levels of education, training, and didactic and research experience.

The second through third year of each scholar’s program should consist of: (1) a “hands-on” research experience (e.g., protocol development, data analysis, and report writing) in an existing team research setting, and (2) developing a public health research project to provide experience in grant writing and program management.

Predoctoral Training:  Predoctoral research training must lead to the Ph.D. degree or a comparable research doctoral degree.  Students enrolled in health-professional training programs that wish to postpone their professional studies in order to engage in full-time research training may also be appointed to a GTP grant.  Predoctoral research training must emphasize fundamental training in areas of public health sciences. 

Postdoctoral Training:  Postdoctoral research training is for individuals who have received a Ph.D., D.V.M, D.D.S., M.D., or a comparable doctoral degree from an accredited domestic or foreign institution. Research training at the postdoctoral level must emphasize specialized training to meet national public health research priorities.

GTP grants are a desirable mechanism for the postdoctoral training of physicians and other health professionals who may have extensive medical/epidemiological training but limited research experience.  For such individuals, the training may be a part of a research degree program.  In all cases, postdoctoral scholars should agree to engage in at least 2 years of research, research training, or comparable activities beginning at the time of appointment.  The duration of training has been shown to be strongly correlated with retention in post-training research activity.

Underrepresented Groups: Within the expanded framework of public health research, recruiting individuals from racially or ethnicly under-represented groups is a high priority. Applicants are encouraged to have a detailed plan to address the under-representation of minorities among public health professionals and for the recruitment of under-represented minorities.

See Section VIII, Other Information - Required Federal Citations, for policies related to this announcement.

Section II. Award Information

1. Mechanism(s) of Support

This funding opportunity will use the T01 award mechanism(s).

As an applicant, you will be solely responsible for planning, directing, and executing the proposed project.

This funding opportunity uses just-in-time concepts. This funding opportunity uses the just-in-time budget concepts. It also uses the non-modular budget format described in the PHS 398 application instructions (see A detailed categorical budget for the "Initial Budget Period" and the "Entire Proposed Period of Support" is to be submitted with the application.

2. Funds Available

The participating CIO, OPHR, intends to commit approximately $3 million in total costs in FY 2007 to fund up to three awards. The average award amount will be approximately $1 million in total costs. An applicant may request a project period of up to 24 months. An applicant may request up to $1 million for the first 12-month budget period. The approximate total project period funded amount is $2 million. The anticipated start date for new awards is September 30, 2007.

All estimated funding amounts are subject to availability of funds.

CDC will accept and review applications with budgets greater than the ceiling amount.

Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. Although the financial plans of the CIO (s) provide support for this program, awards pursuant to this funding opportunity are contingent upon the availability of funds and the receipt of a sufficient number of meritorious applications.

Facilities and administrative costs requested by consortium participants are not included in the direct cost limitation; see NOT-OD-05-004.

Section III. Eligibility Information

1. Eligible Applicants

1.A. Eligible Institutions

In 2004, CDC awarded 3 Graduate Training Program grants (T01s) under RFA-CD-04-003 for health protection research training activities.  T01 grants allow institutions of higher education to assist and extend training of individuals preparing for research and academic careers in fundamental, preclinical, clinical, public health, and other disciplines related to the area of interest of the awarding agency. Support is provided for training activities related to the development or enhancement of training programs that provide research training opportunities for individuals, selected by the institution, who are training for careers in specified areas of health protection research. This RFA is a competitive continuation that extends these activities and only current recipients of the initial graduate training grants are eligible to apply. The purpose of these awards is to allow these grantees to build on their current training activities, infrastructure, and capacity. Eligible applicants are: New York University School of Medicine, University of Minnesota, and University of Illinois, Chicago.

Because OPHR’s existing T01 recipients possess the infrastructure and established training and research activities to enable them to build on the existing training programs and because continuity in the training programs is required, this is a limited competition. To recruit competitively, the T01s must have a full year of lead time before the start of a new cycle during which to recruit. This limited competition will allow those research training grant awardees that have been able to substantially and successfully build a training infrastructure and recruit fellows, to compete in fiscal year 2006 for 2007 fiscal year funds to assist them to maximize the output of new fellows and therefore the public health impact of the T01 programs. In addition, ongoing evaluation of the T01 grants requires a longer period of funding be in place for the current awardees in order to determine the appropriate structure for future CDC programs of a similar nature. Results from this RFA should inform CDC, public health professionals, policy makers, and the public about how training programs can fill a critical need in preparing a research workforce dedicated to public health research and practice. Because this RFA is intended to increase the number of trained public health scientists in the US, no awards will be made to foreign institutions.

Eligible institutions may propose a change in Principal Investigator/Program Director. Justification for such changes must be provided.

1.B. Eligible Individuals

Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with their institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for CDC programs.

The Project Director (or Principal Investigator) should have a strong and active track record in research, research training, and administration that demonstrates the skills, knowledge, and experience necessary to implement and manage the proposed training program.  

2. Cost Sharing or Matching

Cost sharing, matching, or cost participation is not required.

The most current Grants Policy Statement can be found at:

3. Other-Special Eligibility Criteria

An applicant institution may only submit one application under this announcement.

If your application is incomplete or non-responsive to the special requirements listed in this section, it will not be entered into the review process.

Note: Title 2 of the United States Code Section 1611 states that an organization described in Section 501(c)(4) of the Internal Revenue Code that engages in lobbying activities is not eligible to receive Federal funds constituting an award, grant, or loan.

Section IV. Application and Submission Information

1. Address to Request Application Information

The PHS 398 application instructions are available at in an interactive format. Applicants must use the currently approved version of the PHS 398. For further assistance contact GrantsInfo, Telephone (301) 710-0267, Email:

CDC Telecommunications for the hearing impaired: TTY 770-488-2783.

2. Content and Form of Application Submission

Applications must be prepared using the most current PHS 398 research grant application instructions and forms. Applications must have a Dun & Bradstreet (D&B) Data Universal Numbering System number as the universal identifier when applying for Federal grants or cooperative agreements. The D&B number can be obtained by calling (866) 705-5711 or through the web site at The D&B number should be entered on line 11 of the face page of the PHS 398 form.

The title and number of this funding opportunity must be typed on line 2 of the face page of the application form and the YES box must be checked.

Supplemental Instructions

All training activities should be consistent with the goals of the CDC and should be based on well -documented health protection needs. In order to assist applicants in the preparation of an application that can be reviewed, some supplemental instructions are provided. Although the T01 mechanism is not considered a Kirschstein-NRSA Program grant, the applicant should follow the special instructions for preparing a NRSA application contained within the PHS 398 instructions. The applicant should follow the page limits specified, and ensure that each training activity is clearly described and identified.  

In order to facilitate the preparation and review of the T01 application, the PHS 398 Substitute Form Page 3 Table of Contents should be followed (“Substitute Table of Contents for Institutional NRSA”).

The application for this program uses the substitute form page 4 (“NRSA Substitute Detailed Budget for Initial Budget Period Direct Costs”) and substitute form page 5 (“NRSA Substitute Budget for Entire Proposed Period of Support Direct Costs”) of the 398 application. Applicants that do not submit the budget in the required format will have their applications returned as non-responsive. Limits on funding levels for each component are listed below in Section IV.6. “Other Submission Requirements.”

Note: Type density and size throughout the entire application must conform to the limits provided on page 14 in the PHS 398 instructions.

3. Submission Dates and Times

All requested information must be received in the CDC Procurement and Grants Office by 4:00 p.m. Eastern Time on the deadline date. If you submit your application by the United States Postal Service or commercial delivery service, you must ensure that the carrier will be able to guarantee delivery by the closing date and time.  If CDC receives your submission after closing due to: (1) carrier error, when the carrier accepted the package with a guarantee for delivery by the closing date and time, or (2) significant weather delays or natural disasters, you will be given the opportunity to submit documentation of the carrier’s guarantee.  If the documentation verifies a carrier problem, CDC will consider the submission as having been received by the deadline. 

This announcement is the definitive guide on LOI and application content, submission address, and deadline.  It supersedes information provided in the application instructions.  If your application does not meet the deadline described in Section IV.3.A, it will not be eligible for review, and will be discarded. You will be notified that you did not meet the submission requirements.

Otherwise, CDC will not notify you upon receipt of your submission.  If you have a question about the receipt of your application, first contact your courier.  If you still have a question, contact the PGO-TIMS staff at: 770-488-2700.  Before calling, please wait two to three days after the submission deadline.  This will allow time for submissions to be processed and logged.

3.A. Receipt, Review and Anticipated Start Dates
Letter of Intent Receipt Date: Not required
Application Receipt Date(s): July 28, 2006
Peer Review Date: September, 2006
Council Review Date: September, 2006
Earliest Anticipated Start Date: September 30, 2007

3.A.1. Letter of Intent

A letter of intent is not required for the funding opportunity.

3.B. Sending an Application

Applications follow the PHS 398 application instructions for content and formatting of your applications.  If the instructions in this announcement differ in any way from the PHS 398 instructions, follow the instructions in this announcement.

Applications must be prepared using the research grant applications found in the PHS 398 instructions for preparing a research grant application. Submit a signed, typewritten original of the application and all appendices, including the checklist, and one signed photocopy in one package to:

Technical Information Management Section – RFA CD07-001
CDC, Procurements and Grants Office
2920 Brandywine Road
Atlanta, GA  30341

At the time of submission, three additional copies of the application, including the appendix material, must be sent to:

LaTanya Jackson
Grants Technical Assistant
Office of the Director/Office of Public Health Research
Centers for Disease Control and Prevention
1600 Clifton Road, MS D-72
Atlanta, GA 30333
Telephone: (404) 639-4821
FAX: (404) 639-4903

3.C. Application Processing

Applications must be received on or before the application receipt date(s) described above (Section IV.3.A.). If an application is received after that date, it will be returned to the applicant without review. Upon receipt, applications will be evaluated for completeness and responsiveness by OPHR and PGO. Incomplete and non-responsive applications will not be reviewed.

CDC will not accept any application in response to this funding opportunity that is essentially the same as one currently pending initial review, unless the applicant withdraws the pending application. However, when a previously unfunded application, originally submitted as an investigator-initiated application, is to be submitted in response to a funding opportunity, it is to be prepared as a NEW application. That is, the application for the funding opportunity must not include an Introduction describing the changes and improvements made, and the text must not be marked to indicate the changes from the previous unfunded version of the application.

4. Intergovernmental Review

Executive Order 12372 does not apply to this program.

5. Funding Restrictions

All CDC awards are subject to the terms and conditions, cost principles, and other considerations described in the PHS Grants Policy Statement.

Additional guidance can be found at NIH Grants Policy Statement.

Restrictions, which must be taken into account while writing your budget, are as follows:

6. Other Submission Requirements

Allowable Costs 

Funds may be requested for:

Stipends:  Funds, in the form of stipends, are provided to graduate students and postdoctoral scholars.  A stipend is provided as a subsistence allowance to help scholars defray living expenses during the research training experience.  It is not provided as a condition of employment with either the Federal Government or the awardee institution.  Stipends must be paid to all scholars at the levels approved by the Secretary of the Department of Health and Human Services.  Stipend levels are adjusted nearly every year and current stipend levels are available on the NIH website at:

The training institution may not alter established stipend levels.  Further, stipend amounts are not to be changed in the middle of an appointment period.  Stipends may be adjusted only at the time of appointment or reappointment.  Finally, stipends must be based on the levels established for the current fiscal year of the grant.  For appointments of less than a full year, the stipend will be based on a monthly or daily pro-ration.  The monthly stipend amount is calculated by dividing the current annual stipend by 12.  The daily stipend is calculated by dividing the current annual stipend by 365.  For postdoctoral scholars the appropriate stipend level is based on the number of FULL years of relevant postdoctoral experience at the time of appointment.  Relevant experience may include research experience (including industrial), teaching, internship, residency, public health duties, or other time spent in full-time studies in a health-related field following the date of the qualifying doctoral degree.

Tuition, Fees, and Health Insurance:  The combined cost of tuition, fees, and health insurance (either self-only or family as appropriate) at the following rate: 100 percent of all costs up to $3,000 and 60 percent of costs above $3,000.  Costs associated with tuition, fees, and health insurance are allowable only if they are applied consistently to all persons in a similar research training status at the institution regardless of the source of support.  A full description of the tuition policy is contained within the Grants Policy Statement at NIH Grants Policy Statement (12/03) - Part II: Terms and Conditions of NIH Grant Awards - Subpart B: Terms and Conditions for Specific Types of Grants, Grantees, and Activities -- File 2 of 5.

Other Scholar Costs: Scholar travel, including attendance at scientific meetings that the institution determines to be necessary to the individual's research training, is an allowable scholar expense.  In addition, support for travel to a research training experience away from the institution may be permitted.  Research training experiences away from the parent institution must be justified considering the type of opportunities for training available, the manner in which these opportunities differ from and complement those offered at the parent institution, and the relationship of the proposed experience to the scholar's career stage and goals.  This type of research training requires prior approval from the CDC.  Letters requesting such training may be submitted to the OPHR at any time during the award period.  Under exceptional circumstances, which can include providing accommodations for a scholar with disabilities, it is possible to request institutional costs above the standard rate.  Requests for additional scholar costs must be explained in detail and carefully justified in the application.  Consultation with OPHR program staff in advance of such requests is strongly advised.

Training Related Expenses: Institutional costs of $2,200 a year per predoctoral scholar and $3,850 a year per postdoctoral scholar may be requested to defray the costs of other research training related expenses, such as staff salaries, consultant costs, equipment, research supplies, and travel expenses for the training faculty.  Training related expenses may be adjusted in future fiscal years.

Facilities and Administrative Costs:  A facilities and administrative allowance (indirect cost allowance) based on 8 percent of total allowable direct costs (this excludes amounts for tuition, fees, health insurance, and equipment) may be requested.  Information on Facilities and Administrative Costs is available in the Grants Policy Statement at NIH Grants Policy Statement (12/03) - Part II: Terms and Conditions of NIH Grant Awards - Subpart A: General -- File 2 of 5.

Stipend Supplementation, Compensation, and Other Income

The grantee institution is allowed to provide funds to an individual in addition to the stipends paid by the CDC.  Such additional amounts either may be in the form of augmented stipends (supplementation) or in the form of compensation, such as salary or tuition remission for services such as teaching or serving as a laboratory assistant, provided the conditions described below are met.  Under no circumstances may the conditions of stipend supplementation or the services provided for compensation interfere with, detract from, or prolong the scholar's approved research training grant program.  Stipend Supplementation: Supplementation or additional support to offset the cost of living may be provided by the grantee institution. Supplementation does not require additional effort from the scholar.  DHHS funds may not be used for supplementation under any circumstances.  Additionally, no funds from other Federal agencies may be used for supplementation unless specifically authorized by the CDC and the other Federal Agency.  

Compensation:  An institution may provide additional funds to a scholar in the form of compensation (as salary and/or tuition remission) for services such as teaching or serving as a research assistant.  A scholar may receive compensation for services as a research assistant or in some other position on a Federal research grant, including a DHHS research grant.  However, compensated services should occur on a limited, part-time basis apart from the normal research training activities, which require a minimum of 40 hours per week.  In addition, compensation may not be paid from a research grant supporting the research training experience.

Educational Loans or G.I. Bill:  An individual may make use of Federal educational loan funds and assistance under the Veterans Readjustment Benefits Act (G.I. Bill).  Such funds are not considered supplementation or compensation.

Concurrent Awards:  A research training grant may not be held concurrently with another federally sponsored fellowship or similar Federal award that provides a stipend or otherwise duplicates provisions of this grant.

Tax Liability: Section 117 of the Internal Revenue Code applies to the tax treatment of all scholarships and fellowships.  Under that section, non-degree candidates are required to report as gross income any monies paid on their behalf for stipends, or any course tuition and fees required for attendance.  Degree candidates may exclude from gross income (for tax purposes) any amount used for tuition and related expenses such as fees, books, supplies, and equipment required for courses of instruction at a qualified educational organization.  The taxability of stipends, however, in no way alters the relationship between scholar and institutions.  The stipends are not considered salaries.  In addition, scholars supported under the grant are not considered to be in an employee-employer relationship with the CDC or the awardee institution.  It is therefore, inappropriate and unallowable for institutions to charge costs associated with employment (such as FICA, workman's compensation, or unemployment insurance) to the training grant.  It must be emphasized that the interpretation and implementation of the tax laws are the domain of the Internal Revenue Service (IRS) and the courts.  The CDC takes no position on the status of a particular taxpayer, and it does not have the authority to dispense tax advice.  Individuals should consult their local IRS office about the applicability of the law to their situation and for information on their tax obligations.


In general, scholars may receive stipends during the normal periods of vacation and holidays observed by individuals in comparable training positions at the grantee institution. For the purpose of these awards, however, the period between the spring and fall semesters is considered an active time of research and research training and is not considered to be a vacation or holiday.  Scholars may receive stipends for up to 15 calendar days of sick leave per year.  Sick leave may be used for the medical conditions related to pregnancy and childbirth.  Scholars may also receive stipends for up to 30 calendar days of parental leave per year for the adoption or the birth of a child when those in comparable training positions at the grantee institution have access to paid leave for this purpose and the use of parental leave is approved by the program director.

A period of terminal leave is not permitted and payment may not be made from grant funds for leave not taken.  Individuals requiring periods of time away from their research training experience longer than specified here must seek approval from the CDC for an unpaid leave of absence.  At the beginning of a leave of absence, the scholars must submit a Termination Notice (PHS Form 416-7) and upon return from the leave of absence, the scholars must be formally reappointed to the grant by submitting an updated Statement of Appointment (PHS Form 2271). 

Part-time Training

Under unusual and pressing personal circumstances, a Program Director may submit a written request to the awarding component to change a scholar appointment to less than full-time.  Such requests will be considered on a case-by-case basis and must be approved by the CDC for each budget period.  The nature of the circumstances requiring the part-time training might include medical conditions, disability, or pressing personal or family situations such as child or elder care.  Permission for part-time training will not be approved to accommodate other sources of funding, job opportunities, public health practice, public health training, or for other responsibilities associated with the scholars' position at the institution.  In each case, the Program Director must submit a written request countersigned by the scholars and an appropriate institutional business official that includes documentation supporting the need for part-time training.  The written request also must include an estimate of the expected duration of the period of part-time training, an assurance that the scholars intends to return to full-time training when that becomes possible, and an assurance that the scholar intends to complete the research training program. In no case will it be permissible for the scholar to be engaged in supported research training for less than 50 percent effort.  Individuals who must reduce their commitment to less than 50 percent effort must take a leave-of-absence from training grant support.  The stipend will be pro-rated in the grant award during the period of any approved part-time training.

If you are requesting indirect costs in your budget, you must include a copy of your indirect cost rate agreement.  If your indirect cost rate is a provisional rate, the agreement should be less than 12 months of age. 

Your research training plan should address activities to be conducted over the entire project period.

Plan for Sharing Research Data

The precise content of the data-sharing plan will vary, depending on the data being collected and how the investigator is planning to share the data. Applicants may wish to describe briefly the expected schedule for data sharing, the format of the final dataset, the documentation to be provided, whether or not any analytic tools also will be provided, whether or not a data-sharing agreement will be required and, if so, a brief description of such an agreement (including the criteria for deciding who can receive the data and whether or not any conditions will be placed on their use), and the mode of data sharing (e.g., under their own auspices by mailing a disk or posting data on their institutional or personal website, through a data archive or enclave). References to data sharing may also be appropriate in other sections of the application.

All applicants must include a plan for sharing research data in their application. The data sharing policy is available at under Additional Requirements 25 Release and Sharing of Data. All investigators responding to this funding opportunity should include a description of how final research data will be shared, or explain why data sharing is not possible.

The reasonableness of the data sharing plan or the rationale for not sharing research data will be assessed by the reviewers. However, reviewers will not factor the proposed data sharing plan into the determination of scientific merit or the priority score.

Sharing Research Resources
Not applicable

Section V. Application Review Information

1. Criteria

Only the review criteria described below will be considered in the review process.

The following will be considered in making funding decisions:

2. Review and Selection Process

Applications that are complete and responsive to the RFA will be evaluated for scientific and technical merit by an appropriate peer review group convened by OPHR in accordance with the review criteria stated below.

As part of the initial merit review, all applications will:

The goals of CDC-supported research are to advance the understanding of health promotion and prevention of disease, injury, and disability, and enhance preparedness.  In the written comments, reviewers will be asked to evaluate the application in order to judge the likelihood that the proposed research will have a substantial impact on the pursuit of these goals. 

Review Criteria for Training Programs

The scientific review group will address and consider each of these criteria in assigning the application's overall score, weighting them as appropriate for each application.  The application does not need to be strong in all categories to be judged likely to have major scientific and technical merit and thus deserve a high priority score.

Program Justification: The potential impact of the program in meeting the regional and national needs for public health training.

Past Performance: The adequacy of the record of the program in training and the success of graduates as documented in part by the required table that includes numbers of trainees, length of training, employment history, placement, and location and type of placement. Past research training record of both the program and the designated preceptors as determined by the success of former trainees in seeking further career development and in establishing productive scientific careers.  Evidence of further career development can include receipt of fellowships, career awards, further training appointments, and similar accomplishments.  Evidence of a productive scientific career can include a record of successful competition for research grants, receipt of special honors or awards, a record of publications, receipt of patents, promotion to scientific positions, and any other measure of success consistent with the nature and duration of the training received.

Approach: Objectives, design, and direction of the research training program.

Innovation: The degree of innovation of the program. Does the academic program involve new and innovative approaches to training and education relevant to the occupational safety and health field?

Training Staff: Caliber of preceptors as researchers, including successful competition for research support in areas directly related to the proposed research training program.

Environment: Quality of the institutional training environment for supported trainees and the relationship of the training program to the broader training program (if appropriate). The level of institutional commitment, quality of the facilities, availability of appropriate courses, and the availability of research and research training support.

Candidates: Quality of the applicant pool and the selection of individuals for appointment to the training program.  This assessment will include a consideration of the racial and ethnic diversity of the trainee pool, but will take into account the described recruitment and retention efforts as well as the availability of individuals from underrepresented groups within the relevant pool of applicants.

Evaluation and Tracking:  Adequacy of the plans for evaluate the performance of the program as a whole (e.g., quality of the didactic cores, adequacy of the performance of mentors, adequacy of faculty participation), and to make changes that improve performance and outcomes.  Adequacy of the plans to track career outcomes of scholars, including positions held, papers published, grants and awards submitted/obtained, and other relevant information.  Annual and close out reports will be required to include evaluation measures as specified in the evaluation plan.

2.A. Additional Review Criteria:

In addition to the above criteria, the following items will continue to be considered in the determination of scientific merit and the priority score:

Protection of Human Subjects from Research Risk: The involvement of human subjects and protections from research risk relating to their participation in the proposed research will be assessed (see the Research Plan, Section E on Human Subjects in the PHS Form 398). Additional CDC Requirements under AR-1 Human Subjects Requirements can be found on

Inclusion of Women and Minorities in Research:

Does the application adequately address the CDC Policy requirements regarding the inclusion of women, ethnic, and racial groups in the proposed research?  This includes: (1) The proposed plan for the inclusion of both sexes and racial and ethnic minority populations for appropriate representation; (2) The proposed justification when representation is limited or absent; (3) A statement as to whether the design of the study is adequate to measure differences when warranted; and (4) A statement as to whether the plans for recruitment and outreach for study participants include the process of establishing partnerships with community(ies) and recognition of mutual benefits.

Care and Use of Vertebrate Animals in Research: If vertebrate animals are to be used in the project, the five items described under Section F of the PHS Form 398 research grant application instructions will be assessed. Additional CDC Requirements under AR-3 Animal Subjects Requirements can be found on

Biohazards: If materials or procedures are proposed that are potentially hazardous to research personnel and/or the environment, determine if the proposed protection is adequate.

2.B. Additional Review Considerations

Budget: The reasonableness of the proposed budget and the requested period of support in relation to the proposed research. The priority score should not be affected by the evaluation of the budget.

2.C. Sharing Research Data

Data Sharing Plan: The reasonableness of the data sharing plan or the rationale for not sharing research data will be assessed by the reviewers. However, reviewers will not factor the proposed data sharing plan into the determination of scientific merit or the priority score. The presence of a data sharing plan will be part of the terms and conditions of the award. The funding organization will be responsible for monitoring the data sharing policy.

2.D. Sharing Research Resources

Not applicable

3. Anticipated Announcement and Award Dates

Not applicable

Section VI. Award Administration Information

1. Award Notices

After the peer review of the application is completed, the Principal Investigator will also receive a written critique called a Summary Statement.

Those applicants under consideration for funding will be contacted by CDC for additional information.

A formal notification in the form of a Notice of Award (NoA) will be provided to the applicant organization.  The NoA signed by the Grants Management Officer (GMO) is the authorizing document.  This document will be mailed and/or emailed to the recipient fiscal officer identified in the application. 

Selection of the application for award is not an authorization to begin performance.  Any cost incurred before receipt of the NoA is at the recipient’s risk.  These costs may be reimbursed only to the extent considered allowable pre-award costs.  See also Section IV.5. Funding Restrictions.

2. Administrative and National Policy Requirements

The Code of Federal Regulations 45 CFR Part 74 and Part 92 have details about policy requirements.  For more information on the Code of Federal Regulations, see the National Archives and Records Administration at the following Internet address: Additional requirements can be found in Section VIII. Other Information of this document or on the CDC website at the following Internet address: These will be incorporated into the NoA by reference.

3. Reporting

You must provide CDC with an original, plus two hard copies of the following reports:

  1. Interim/Grant Progress Report, (use form PHS 2590, OMB Number 0925-0001, rev. 9/04 as posted on the CDC website) no less than 120 days prior to the end of the current budget period.  The progress report will serve as your non-competing continuation application.
  2. Financial status report, no more than 90 days after the end of the budget period.
  3. Final financial and performance reports, no more than 90 days after the end of the project period.

These reports must be forwarded by U.S. Postal Service or Express Delivery to the Grants Management Specialist listed in the “Agency Contacts” section of this announcement.

Section VII. Agency Contacts

We encourage your inquiries concerning this funding opportunity and welcome the opportunity to answer questions from potential applicants. Inquiries may fall into three areas: scientific/research, peer review, and financial or grants management issues:

1. Scientific/Research Contacts:

Juliana K. Cyril, PhD, MPH
Scientific Program Administrator
Office of Public Health Research
Centers for Disease Control and Prevention
1600 Clifton Road, MS D-72
Atlanta, GA 30333
Telephone: 404-639-4639
FAX: 404-639-4903

2. Peer Review Contacts:

Christine Morrison, PhD
Scientific Review Administrator
Office of Public Health Research
Centers for Disease Control and Prevention
1600 Clifton Road, MS D-72
Atlanta, GA 30333
Telephone: (404) 639-3098
FAX: (404) 639-4903

3. Financial or Grants Management Contacts:

Mattie B. Jackson
Grants Management Specialist
Procurement and Grants Office
Centers for Disease Control and Prevention
2920 Brandywine Road
Atlanta, GA 30341
Telephone: (770) 488-2696
FAX: (770)488-2670

4. General Questions Contacts:

Technical Information Management Section

Procurement and Grants Office
Centers for Disease Control and Prevention (CDC)
2920 Brandywine Road
Atlanta, GA  30341
Telephone:  770-488-2700

Section VIII. Other Information

Required Federal Citations

Human Subjects Protection:
Federal regulations (45CFR46) require that applications and proposals involving human subjects must be evaluated with reference to the risks to the subjects, the adequacy of protection against these risks, the potential benefits of the research to the subjects and others, and the importance of the knowledge gained or to be gained (   Additional CDC Requirements under AR-1 Human Subjects Requirements can be found on

Use of Animals in Research:
Recipients of PHS support for activated involving live, vertebrate animals must comply with PHS Policy on Humane Care and Use of Laboratory Animals ( as mandated by the Health Research Extension Act of 1985 (, and the USDA Animal Welfare Regulations ( as applicable.  Additional CDC Requirements under AR-3 Animal Subjects Requirements can be found on

Requirements for Inclusion of Women and Racial and Ethnic Minorities in Research

It is the policy of the Centers for Disease Control and Prevention (CDC) and the Agency for Toxic Substances and Disease Registry (ATSDR) to ensure that individuals of both sexes and the various racial and ethnic groups will be included in CDC/ATSDR-supported research projects involving human subjects, whenever feasible and appropriate. Racial and ethnic groups are those defined in OMB Directive No. 15 and include American Indian or Alaska Native, Asian, Black or African American, Hispanic or Latino, Native Hawaiian or Other Pacific Islander. Applicants shall ensure that women, racial and ethnic minority populations are appropriately represented in applications for research involving human subjects. Where clear and compelling rationale exist that inclusion is inappropriate or not feasible, this situation must be explained as part of the application. This policy does not apply to research studies when the investigator cannot control the race, ethnicity, and/or sex of subjects. Further guidance to this policy is contained in the Federal Register, Vol. 60, No. 179, pages 47947-47951, and dated Friday, September 15, 1995.

HIV/AIDS Confidentiality Provisions

Recipients must have confidentiality and security provisions to protect data collected through HIV/AIDS surveillance, including copies of local data release policies; employee training in confidentiality provisions; State laws, rules, or regulations pertaining to the protection or release of surveillance information; and physical security of hard copies and electronic files containing confidential surveillance information.

Describe laws, rules, regulations, or health department policies that require or permit the release of patient-identifying information collected under the HIV/AIDS surveillance system to entities outside the public health department; describe also the measures the health department has taken to ensure that persons reported to the surveillance system are protected from further or unlawful disclosure.

Some projects may require Institutional Review Board (IRB) approval or a certificate of confidentiality.

HIV Program Review Panel Requirements

Compliance with Content of AIDS-Related Written Materials, Pictorials, Audiovisuals, Questionnaires, Survey Instruments, and Educational Sessions (June 1992) is required.

To meet the requirements for a program review panel, you are encouraged to use an existing program review panel, such as the one created by the State health department's HIV/AIDS prevention program. If you form your own program review panel, at least one member must be an employee (or a designated representative) of a State or local health department. List the names of the review panel members on the Assurance of Compliance form, CDC 0.1113. Submit the program review panel's report that all materials have been approved.

If the proposed project involves hosting a conference, submit the program review panel's report stating that all materials, including the proposed conference agenda, have been approved. Submit a copy of the proposed agenda with the application.

Before funds are used to develop educational materials, determine whether suitable materials already exist in the CDC National AIDS Clearinghouse.

Patient Care

Ensure that all STD or HIV infected patients enrolled in the proposed project will be linked to an appropriate local care system that can address their specific needs, such as medical care, counseling, social services, and therapy.

Executive Order 12372 Review

Applications are subject to Intergovernmental Review of Federal Programs, as governed by Executive Order (E.O.) 12372. The order sets up a system for State and local governmental review of proposed Federal assistance applications. Applicants should contact their State single point of contact (SPOC) as early as possible to alert the SPOC to prospective applications and to receive instructions on the State process. For proposed projects serving more than one State, the applicant is advised to contact the SPOC for each State affected.

Click on the following link to get the current SPOC list

Indian tribes must request tribal government review of their applications.

SPOCs or tribal governments that have recommendations about an application submitted to CDC should send them, in a document bearing the program announcement number, no more than 60 days after the application deadline date, to:

Sharron Orum, Grants Management Specialist
Procurement and Grants Office
Announcement Number RFA CD07-001
Centers for Disease Control and Prevention (CDC)
2920 Brandywine Road
Atlanta, Georgia 30341-4146

CDC does not guarantee to accept or justify its non-acceptance of recommendations that are received more than 60 days after the application deadline.

Public Health System Reporting Requirements

This program is subject to the Public Health System Reporting Requirements. Under these requirements, all community-based non-governmental organizations submitting health services applications must prepare and submit the items identified below to the head of the appropriate State and/or local health agency(s) in the program area(s) that may be impacted by the proposed project no later than the application deadline date of the Federal application. The appropriate State and/or local health agency is determined by the applicant. The following information must be provided:

If the State and/or local health official should desire a copy of the entire application, it may be obtained from the State Single Point of Contact (SPOC) or directly from the applicant.

Paperwork Reduction Act Requirements

Under the Paperwork Reduction Act, projects that involve the collection of information from 10 or more individuals and funded by a grant or a cooperative agreement will be subject to review and approval by the Office of Management and Budget (OMB).

Smoke-Free Workplace Requirements

CDC strongly encourages all recipients to provide a smoke-free workplace and to promote abstinence from all tobacco products. Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities that receive Federal funds in which education, library, day care, health care, or early childhood development services are provided to children.

Healthy People 2010

The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010," a PHS-led national activity for setting priority areas. This PA is related to one or more of the priority areas. Potential applicants may obtain a copy of "Healthy People 2010" at

Lobbying Restrictions

Applicants should be aware of restrictions on the use of HHS funds for lobbying of Federal or State legislative bodies. Under the provisions of 31 U.S.C. Section 1352, recipients (and their sub-tier contractors) are prohibited from using appropriated Federal funds (other than profits from a Federal contract) for lobbying congress or any Federal agency in connection with the award of a particular contract, grant, cooperative agreement, or loan. This includes grants/cooperative agreements that, in whole or in part, involve conferences for which Federal funds cannot be used directly or indirectly to encourage participants to lobby or to instruct participants on how to lobby.

In addition no part of CDC appropriated funds, shall be used, other than for normal and recognized executive-legislative relationships, for publicity or propaganda purposes, for the preparation, distribution, or use of any kit, pamphlet, booklet, publication, radio, television, or video presentation designed to support or defeat legislation pending before the Congress or any State or local legislature, except in presentation to the Congress or any State or local legislature itself. No part of the appropriated funds shall be used to pay the salary or expenses of any grant or contract recipient, or agent acting for such recipient, related to any activity designed to influence legislation or appropriations pending before the Congress or any State or local legislature.

Any activity designed to influence action in regard to a particular piece of pending legislation would be considered "lobbying." That is lobbying for or against pending legislation, as well as indirect or "grass roots" lobbying efforts by award recipients that are directed at inducing members of the public to contact their elected representatives at the Federal or State levels to urge support of, or opposition to, pending legislative proposals is prohibited. As a matter of policy, CDC extends the prohibitions to lobbying with respect to local legislation and local legislative bodies.

The provisions are not intended to prohibit all interaction with the legislative branch, or to prohibit educational efforts pertaining to public health. Clearly there are circumstances when it is advisable and permissible to provide information to the legislative branch in order to foster implementation of prevention strategies to promote public health. However, it would not be permissible to influence, directly or indirectly, a specific piece of pending legislation

It remains permissible to use CDC funds to engage in activity to enhance prevention; collect and analyze data; publish and disseminate results of research and surveillance data; implement prevention strategies; conduct community outreach services; provide leadership and training, and foster safe and healthful environments.

Recipients of CDC grants and cooperative agreements need to be careful to prevent CDC funds from being used to influence or promote pending legislation. With respect to conferences, public events, publications, and "grassroots" activities that relate to specific legislation, recipients of CDC funds should give close attention to isolating and separating the appropriate use of CDC funds from non-CDC funds. CDC also cautions recipients of CDC funds to be careful not to give the appearance that CDC funds are being used to carry out activities in a manner that is prohibited under Federal law.

Prohibition on Use of CDC Funds for Certain Gun Control Activities

The Departments of Labor, Health and Human Services, and Education, and Related Agencies Appropriations Act specifies that: "None of the funds made available for injury prevention and control at the Centers for Disease Control and Prevention may be used to advocate or promote gun control."

Anti-Lobbying Act requirements prohibit lobbying Congress with appropriated Federal monies. Specifically, this Act prohibits the use of Federal funds for direct or indirect communications intended or designed to influence a member of Congress with regard to specific Federal legislation. This prohibition includes the funding and assistance of public grassroots campaigns intended or designed to influence members of Congress with regard to specific legislation or appropriation by Congress.

In addition to the restrictions in the Anti-Lobbying Act, CDC interprets the language in the CDC's Appropriations Act to mean that CDC's funds may not be spent on political action or other activities designed to affect the passage of specific Federal, State, or local legislation intended to restrict or control the purchase or use of firearms.

Accounting System Requirements

The services of a certified public accountant licensed by the State Board of Accountancy or the equivalent must be retained throughout the project as a part of the recipient's staff or as a consultant to the recipient's accounting personnel. These services may include the design, implementation, and maintenance of an accounting system that will record receipts and expenditures of Federal funds in accordance with accounting principles, Federal regulations, and terms of the cooperative agreement or grant.

Capability Assessment

It may be necessary to conduct an on-site evaluation of some applicant organization's financial management capabilities prior to or immediately following the award of the grant or cooperative agreement. Independent audit statements from a Certified Public Accountant (CPA) for the preceding two fiscal years may also be required.

Proof of Non-profit Status

Proof of nonprofit status must be submitted by private nonprofit organizations with the application. Any of the following is acceptable evidence of nonprofit status: (a) a reference to the applicant organization's listing in the Internal Revenue Service's (IRS) most recent list of tax-exempt organizations described in section 501(c)(3) of the IRS Code; (b) a copy of a currently valid IRS tax exemption certificate; (c) a statement from a State taxing body, State Attorney General, or other appropriate State Official certifying that the applicant organization has a nonprofit status and that none of the net earnings accrue to any private shareholders or individuals; (d) a certified copy of the organization's certificate of incorporation or similar document that clearly establishes nonprofit status; (e) any of the above proof for a State or national parent organization and a statement signed by the parent organization that the applicant organization is a local nonprofit affiliate.

Security Clearance Requirement

All individuals who will be performing work under a grant or cooperative agreement in a CDC-owned or leased facility (on-site facility) must receive a favorable security clearance, and meet all security requirements. This means that all awardee employees, fellows, visiting researchers, interns, etc., no matter the duration of their stay at CDC must undergo a security clearance process.

Small, Minority, And Women-owned Business

It is a national policy to place a fair share of purchases with small, minority and women-owned business firms. The Department of Health and Human Services is strongly committed to the objective of this policy and encourages all recipients of its grants and cooperative agreements to take affirmative steps to ensure such fairness. In particular, recipients should:

  1. Place small, minority, women-owned business firms on bidders mailing lists.
  2. Solicit these firms whenever they are potential sources of supplies, equipment, construction, or services.
  3. Where feasible, divide total requirements into smaller needs, and set delivery schedules that will encourage participation by these firms.
  4. Use the assistance of the Minority Business Development Agency of the Department of Commerce, the Office of Small and Disadvantaged Business Utilization, DHHS, and similar state and local offices.

Research Integrity

The signature of the institution official on the face page of the application submitted under this Funding Opportunity Announcement is certifying compliance with the Department of Health and Human Services (DHHS) regulations in Title 42 Part 93, Subparts A-E, entitled PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT.

The regulation places requirements on institutions receiving or applying for funds under the PHS Act that are monitored by the DHHS Office of Research Integrity (

For example:

Section 93.301 Institutional assurances.(a) General policy. An institution with PHS supported biomedical or behavioral research, research training or activities related to that research or research training must provide PHS with an assurance of compliance with this part, satisfactory to the Secretary. PHS funding components may authorize [[Page 28389]] funds for biomedical and behavioral research, research training, or activities related to that research or research training only to institutions that have approved assurances and required renewals on file with ORI. (b) Institutional Assurance. The responsible institutional official must assure on behalf of the institution that the institution-- (1) Has written policies and procedures in compliance with this part for inquiring into and investigating allegations of research misconduct; and (2) Complies with its own policies and procedures and the requirements of this part.

Compliance with Executive Order 13279

Faith-based organization are eligible to receive federal financial assistance, and their applications are evaluated in the same manner and using the same criteria as those for non-faith-based organizations in accordance with Executive Order 13279, Equal Protection of the Laws for Faith-Based and Community Organizations.  All applicants should, however, be aware of restrictions on the use of direct financial assistance from the Department of Health and Human Services (DHHS) for inherently religious activities. Under the provisions of Title 45, Parts 74, 87, 92 and 96, organizations that receive direct financial assistance from DHHS under any DHHS program may not engage in inherently religious activities, such as worship, religious instruction, or proselytization as a part of the programs or services funded with direct financial assistance from DHHS.  If an organization engages in such activities, it must offer them separately, in time or location, from the programs or services funded with direct DHHS assistance, and participation must be voluntary for the beneficiaries of the programs or services funded with such assistance.  A religious organization that participates in the DHHS funded programs or services will retain its independence from Federal, State, and local governments, and may continue to carry out its mission, including the definition, practice, and expression of its religious beliefs, provided that it does not use direct financial assistance from DHHS to support inherently religious activities such as those activities described above.  A faith-based organization may, however, use space in its facilities to provide programs or services funded with financial assistance from DHHS without removing religious art, icons, scriptures, or other religious symbols.  In addition, a religious organization that receives financial assistance from DHHS retains its authority over its internal governance, and it may retain religious terms in its organization=s name, select its board members on a religious basis, and include religious references in its organization=s mission statements and other governing documents in accordance with all program requirements, statutes, and other applicable requirements governing the conduct of DHHS funded activities.  For further guidance on the use of DHHS direct financial assistance see Title 45, Code of Federal Regulations, Part 87, Equal Treatment for Faith-Based Organizations, and visit the internet site:

Health Insurance Portability and Accountability Act Requirements

Recipients of this grant award should note that pursuant to the Standards for Privacy of Individually Identifiable Health Information promulgated under the Health Insurance Portability and Accountability Act (HIPAA) (45 CFR Parts 160 and 164) covered entities may disclose protected health information to public health authorities authorized by law to collect or receive such information for the purpose of preventing or controlling disease, injury, or disability, including, but not limited to, the reporting of disease, injury, vital events such as birth or death, and the conduct of public health surveillance, public health investigations, and public health interventions.  The definition of a public health authority includes a person or entity acting under a grant of authority from or contract with such public agency.  CDC considers this project a public health activity consistent with the Standards for Privacy of Individually Identifiable Health Information and CDC will provide successful recipients a specific grant of public health authority for the purposes of this project.

Release and Sharing of Data

The Data Release Plan is the Grantee's assurance that the dissemination of any and all data collected under the CDC data sharing agreement will be released as follows:

  1. In a timely manner.
  2. Completely, and as accurately as possible.
  3. To facilitate the broader community.
  4. Developed in accordance with CDC policy on Releasing and Sharing Data.

April 16, 2003,, and in full compliance with the 1996 Health Insurance Portability and Accountability Act (HIPPA), (where applicable), The Office of Management and Budget Circular A110, (2000) revised 2003, and Freedom of Information Act (FOIA)

Applications must include a copy of the applicant's Data Release Plan.  Applicants should provide CDC with appropriate documentation on the reliability of the data.  Applications submitted without the required Plan may be ineligible for award.  Award will be made when reviewing officials have approved an acceptable Plan.  The successful applicant and the Program Manager will determine the documentation format.  CDC recommends data is released in the form closest to micro data and one that will preserve confidentiality. 

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