Full Text PAR-97-094
NIH GUIDE, Volume 26, Number 27, August 15, 1997
PA NUMBER:  PAR-97-094


National Institute of Dental Research
Application Receipt Dates:  April 5, August 5, December 5
The National Institute of Dental Research (NIDR) seeks through this
Program Announcement (PA) new National Research Service Award (NRSA)
applications for an Individual Predoctoral Dental Scientist
Fellowship (PDSF).  The purpose of the PDSF is to offer an integrated
dental and graduate research training program that leads to
attainment of both the D.D.S./D.M.D. and Ph.D. degrees. The PDSF
provides an approach to expanding the cadre of well-trained oral
health scientists by stimulating early commitment to research careers
by outstanding dental students.  The NIDR anticipates that graduates
of the PDSF will be able to bring into clinical studies of dental,
oral and craniofacial health and disease fundamental knowledge and
insight from the basic biomedical, behavioral and social sciences, as
well as from related fields such as biomimetics, tissue engineering,
biostatistics, epidemiology, health services research and the
computer and information sciences.
For many years, there has been a recognized need to train and develop
clinician-scientists capable of understanding and pursuing dental,
oral and craniofacial health research from the basic, behavioral and
clinical perspectives.  In particular, such researchers can elucidate
essential biological processes and apply this knowledge to the
prevention, diagnosis, management, care and treatment of individual
patients.  To facilitate development of clinician-scientists at the
predoctoral level, the NIDR started in 1996 the Institutional Dental
Scientist Training Program (DSTP).  This mechanism provides funds to
dental schools which then select two students per year to pursue
concurrently the D.D.S./D.M.D. and Ph.D. degrees in an integrated,
interdisciplinary program. At present there are three dental schools
(State University of New York at Buffalo, University of California at
San Francisco and University of Connecticut) which conduct this
program.  At the postdoctoral level, the NIDR has supported since the
mid-1980s the Institutional Dentist Scientist Award (DSA), the
Mentored Clinical Scientist Development Award (formerly known as the
Individual Dentist Scientist Award or Physician Scientist Award for
Dentists) and the Institutional Postdoctoral NRSA.  These mechanisms
support dentists to obtain the Ph.D. in a research field related to
dental, oral and craniofacial health and disease as well as advanced
clinical training in a dental specialty.
There has been a noticeable decrease over the past few years in the
number of highly qualified dentists applying to the postdoctoral
Institutional DSA and NRSA programs. Given the implications of such a
decline for the future viability of oral health research, the NIDR
has embarked on several activities to improve the situation. NIDR
staff have communicated with many dental students and recent
graduates who are currently involved in research about their
perceived obstacles for pursuing a research career.  The major reason
indicated by most students and recent graduates is the large
indebtedness (over $100,000 at some private institutions) with which
dentists are burdened upon graduation. However, some of the best and
brightest students in dental schools throughout the United States
have indicated that they might be more interested in a research
career if provided with some financial support while in school,
thereby decreasing their level of debt upon graduation.  To address
this issue and thereby stimulate greater interest in a research
career among the most outstanding dental students, the NIDR is
proposing in this Program Announcement (PA) an individual Predoctoral
Dental Scientist Fellowship Program (PDSF) which would enable
students attending any dental school in the United States to obtain
both the Ph.D. and dental degree through the NRSA mechanism.  This
mechanism would decrease the amount that students would have to pay
while in dental and graduate school and thus their level of
indebtedness by providing at least partial tuition payment, covering
some educational expenses and paying an annual stipend.
The PDSF is patterned after the Individual Predoctoral NRSA
Fellowship for M.D./Ph.D. (F30 mechanism) currently supported by the
National Institute of Mental Health, National Institute on Drug Abuse
and the National Institute on Alcohol Abuse and Alcoholism. This
model provides individual NRSA fellowships to students in medical
school for pursuit of the MD and Ph.D. degrees in an integrated
Research areas in which the PDSF students are trained must be
relevant to the goals of the NIDR, which are to understand, prevent,
diagnose and treat dental, oral and craniofacial diseases and
disorders. Current special areas of interest include: (i) inherited
diseases and disorders, including the development of teeth and bone;
(ii) emerging and re-emerging infectious diseases, including
bacterial, viral, fungal and parasitic disorders and AIDS; (iii)
neoplastic diseases; (iv) chronic disabling diseases, such as
osteoporosis and related bone disorders, temporomandibular joint
disorders, pain, neuropathies and neurodegenerative diseases and
other systemic disorders with oral manifestations; (v) biomimetics,
tissue engineering and biomaterials; and (vi) behavior, health
promotion and the environment.
The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000",
a PHS-led national activity for setting priority areas.  This PA for
the Individual Predoctoral Dental Scientist Fellowship is related to
the priority area of oral health.  Potential applicants may obtain a
copy of "Healthy People 2000" (Full Report: Stock No. 017-001-00474-0
or Summary Report: Stock No. 017-001-00473-1) through the
Superintendent of Documents, Government Printing Office, Washington,
DC 20402-9325 (telephone 202/512-1800).
At the time of award, fellows must be citizens or non-citizen
nationals of the United States, or have been lawfully admitted to the
United States for permanent residence and have in their possession an
Alien Registration Receipt card (I-551).  Noncitizen nationals are
persons born in lands that are not States, but are under United
States sovereignty, jurisdiction, or administration (e.g., American
Samoa).  Individuals on temporary or student visas are not eligible.
Racial/ethnic minority individuals, women and persons with
disabilities are strongly encouraged to apply.
An applicant for the PDSF must show evidence of both high academic
performance in the biological, chemical, physical or
behavioral/social sciences and significant interest in research. When
the application is submitted, the applicant must meet at least the
following requirements: [a] be enrolled in a formal program at an
approved dental school that leads to the award of a DDS or DMD; [b]
have been accepted in a Ph.D. (or an equivalent degree) program in
one of the research fields listed above in the Background section
related to dental, oral and craniofacial health and disease; and [c]
have a confirmed mentor in that scientific field.  Trainees must
begin their PDSF not later than the third year of dental school,
although preference will be given to starting in the individual~s
first or second year.  In addition, all fellows must have received a
baccalaureate degree by the beginning date of their appointment.
Individuals currently enrolled in a joint D.D.S./D.M.D.- Ph.D.
program are eligible for consideration as trainees.  Individuals who
obtained a Ph.D. prior to entering dental school and desire to pursue
another research doctorate while in dental school are not eligible.
An individual may not have more than one NRSA competing application
pending with the Public Health Service concurrently.
Although NRSAs are not usually meant or intended for study leading to
the D.D.S./D.M.D. or for study that is part of residency training
leading to a dental specialty, this  program is specifically designed
to support training in an established, combined D.D.S./D.M.D.- Ph.D.
program. The institutional setting must be a domestic, nonprofit
private or public institution.
Awards resulting from this PA will use the NRSA F30 mechanism to
provide combined dental school and predoctoral Ph.D. support for five
years.  No other predoctoral NRSA support may be received during this
time.  Any exception to these limitations requires a waiver from the
Director of the NIDR based on a review of the justification provided
by the individual awardee and his/her sponsor.  In general, written
requests for additional years of support (up to a total of seven
years) will be considered favorably for one year at a time if
justified by adequate progress made by the individual in his/her
program.  Since a fellow~s course of study for the combined degrees
may take longer than seven years, all individuals should consider
other potential sources of support for additional years of training.
Continued support beyond the first year is dependent upon
satisfactory progress toward the combined degree.  Annual reports are
to be provided by the fellow, the Ph.D. department and sponsor and
the dental school.
A.  Dental and Graduate Research Training Program
An individual PDSF must provide integrated clinical and graduate
research training required to obtain the D.D.S./D.M.D. and Ph.D.
degrees and to pursue the investigation of dental, oral and
craniofacial health and diseases.  Each fellow~s program must offer
two distinct and integrated components.  A clinical component must
ensure the acquisition of requisite clinical knowledge and technical
expertise in order to meet the requirements for a D.D.S./D.M.D.
degree and to obtain a license to practice dentistry.  A science
field component must be a doctoral (Ph.D. or equivalent) level
program that ensures development of knowledge and research skills in
scientific areas relevant to dental, oral and craniofacial health and
disease.  Current areas are stated in the Background section. The
interdisciplinary program for the fellow should maximize the research
and educational resources of his/her academic institution(s) and any
collaborating organizations.  The program should be tailored to meet
the unique research and clinical development needs of the fellow and
ensure that the individual completes the program with requisite
competencies.  The sequence in which the two components are offered
and their integration should be based on the specific circumstances
and organization of the training institution and should represent
what is deemed most desirable, feasible, and efficient by the
administration of the dental and graduate institutions.
Each fellow must have a mentor, an accomplished investigator active
in the proposed area, to guide the person's development and research
project.  Usually, a mentor will be the doctoral thesis advisor.  The
mentor must be committed to continue this involvement throughout the
individual's total period of development under the award.  A co-
mentor, representing the clinical component, also may be named. Where
feasible, women and minority mentors should be involved as role
All fellows must meet the criteria described in ELIGIBILITY
B.  Allowable Costs
Annual Stipends:  The annual trainee stipend is $11,496 per year
regardless of previous research experience.  A stipend is provided as
a subsistence allowance for the fellow to help defray living expenses
during the research training experience. Stipends may be supplemented
by an institution from non-Federal funds.  Other funds from the PHS,
such as from the NIH, may not be used to supplement stipends.  Non-
PHS Federal funds may be used for stipend supplementation only if
specifically authorized under the terms of the program from which the
supplemental funds are derived.  For example, an individual may make
use of Federal educational loan funds or Department of Veterans'
Affairs benefits when permitted by those programs.  Additional
support may be provided to the fellow without obligation  by the
sponsoring institution or may be conditioned on his or her
performance of certain services such as teaching or serving as a
laboratory assistant. Under no circumstance may the condition of
stipend supplementation detract from or prolong the training.  The
stipend is not a payment  for services performed.  Fellows supported
under individual awards are not considered to be employees either of
the Public Health Service (PHS) or their sponsoring institution, even
though the payment of the stipend is made through the sponsoring
institution.  Stipends are subject to State and Federal income tax.
The taxability  of stipends, however, in no way alters the
relationship between NRSA  fellows and institutions.  NRSA stipends
are not salaries. NRSA fellows are not in an employee-employer
relationship with the  institution in which they are pursuing
research training, nor are they considered to be self-employed.
Stipends are not subject to self-employment tax (FICA).
Tuition, Fees and Health Insurance:  Tuition, fees, and self-only
health insurance are allowable costs if such charges are required of
all individuals in a similar training status at the institution,
regardless of their source of support.  On an annual basis, the
fellowship award will cover 100% of the first $2,000 of the combined
cost of tuition, fees, and self-only health insurance and 60% of any
amount above $2,000.  Up to four years of dental school tuition and
up to four years of graduate school tuition, fees and self-only
health insurance may be requested under this fellowship, but no more
than five years of tuition and fees support in the aggregate can be
awarded unless a waiver is obtained.
Other Training Costs:   Travel, including attendance at scientific
meetings, is an allowable cost at an amount of $800 per year.  In
addition, institutional costs of $1,500 per year may be requested to
defray expenses such as consultant costs, equipment and research
Tax Liability:  The Tax Reform Act of 1986, Public Law 99-514,
affects the tax liability of all individuals supported under the NRSA
program.  The NIH is not in a position to advise students or
institutions about tax liability.  Degree candidates may exclude from
gross income reported for tax  purposes any amount used for tuition
and related expenses such as fees, books, supplies, and equipment
required for courses of instruction at their sponsoring institution.
The business office of the sponsoring institution will be responsible
for the annual preparation and issuance of the IRS form 1099 for
fellows paid through the institution.  NIH will issue the form for
all fellows paid directly by them (fellows training at Federal
Payback Provisions:  Predoctoral trainees do not incur payback
It is the policy of the NIH that women and members of minority groups
and their subpopulations must be included in all NIH supported
biomedical and behavioral research projects involving human subjects,
unless a clear and compelling rationale and justification is provided
that inclusion is inappropriate with respect to the health of the
subjects or the purpose of the research.  This new policy results
from the NIH Revitalization Act of 1993 (Section 492B of Public Law
103-43) and supersedes and strengthens the previous policies
(Concerning the Inclusion of Women in Study Populations, and
Concerning the Inclusion of Minorities in Study Populations) which
have been in effect since 1990.  The new policy contains some new
provisions that are substantially different from the 1990 policies.
All investigators proposing research involving human subjects should
read the "NIH Guidelines For Inclusion of Women and Minorities as
Subjects in Clinical Research," which have been published in the
Federal Register of March 28, 1994 (FR 59 14508-14513), and reprinted
in the NIH GUIDE FOR GRANTS AND CONTRACTS of March 18, 1994, Volume
23, Number 11.
Investigators may obtain copies from these sources or from the
program staff or contact person listed below.  Program staff may also
provide additional relevant information concerning the policy.
Applications are to be submitted on the Individual NRSA grant
application form (PHS 416-1, rev. 8/95).  Application kits are
available at most institutional offices of sponsored research and may
be obtained from: ASKNIH, Extramural Outreach and Information
Resources, National Institutes of Health, 6701 Rockledge Drive MSC
7910, Bethesda, MD 20892-7910; telephone 301/710-0267, email:
At least three completed sealed letters of reference must be
submitted with the application.  Applications without the required
number of reference letters will be returned without review.
Non-citizen applicants must include a notarized statement of
permanent residence indicating possession of an Alien Registration
Receipt Card or at least application for this card.  No award will be
activated without proof of possession.
Applicants are advised to pay special attention to the following
important items in PHS 416-1:
Face Page,  Part I (Prepared by Applicant):
Item 1.  Title of Research Training Proposal.  Type in "Individual
Predoctoral Dental Scientist Fellowship"
Item 2.  Level of Fellowship.  Type in "predoctoral" and the number
of the program announcement.
Item 3.  Leave blank.
Item 5.  Training Under Proposed Award.  Identify the Ph.D.
discipline according to the NIH Lexicon of NRSA disciplines on page
31 of the instructions.
Item 8.  Degree Sought During Proposed Award.  Type in both the
dental (DDS or DMD) and Ph.D. (or equivalent) degrees with expected
completion dates for each.
Item 29a.  Activities Under Award..  Applicants should describe how
they expect to divide their time between dental and  graduate school,
e.g., dental school courses, graduate school  courses, research,
research training, etc., during both the school year and the summer
for each year of the program.
Item 29b.  Research Proposal.  All applicants should provide a
research plan, including a description of a research proposal in
which they will be involved as part of their training. The plan
should include substantive detail that adds to the information about
time allocations requested in Item 29a.  In addition to these items,
applicants should provide scores for all exams relevant to dental and
graduate school  that they have taken recently (e.g., GRE, Dental
Admissions Test, etc.)
Part II (Prepared by Sponsor):
Items 32 and 33.  Sponsor's Previous Fellows/Trainees, Training Plan,
Environment, and Research Facilities.  The sponsor should be funded
currently to conduct independent research (e.g., Principal
Investigator on an R01 or equivalent) and must describe past
experience in the  guidance of other research trainees and fellows.
In addition, the sponsor must describe in detail his/her commitment
to and proposed role in guiding the individual applicant.  The
chairman of the graduate committee for the Ph.D. program also must
describe the department's commitment to and proposed role in guiding
the individual applicant and any modifications to the department's
usual  Ph.D. requirements that are necessary to facilitate this
fellow~s special needs.
The application must include evidence that training in the principles
of responsible conduct of research will be incorporated in the
research experience of each fellow.  This should be presented under
Item 33.  Issues such as conflict of interest, data recording and
retention, professional standards and codes of conduct, responsible
authorship, and ethics in biological and behavioral research can
provide the substantive base of such training.
Application Receipt and Review Schedule
Applications for the PDSF will be accepted and reviewed three times a
year according to the following schedule:
Application Receipt Date:      Apr 5        Aug 5        Dec 5 Review
Meeting:                 Jun/Jul      Oct/Nov      Feb/Mar
Notification:                       Aug/Sept   Dec/Jan      Apr/May
Range of Likely Start Dates:   Sept-Dec    Jan - Mar   May - July
The completed original and two legible copies of the application must
be sent or delivered to:
6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for courier/overnight service)
At the time of submission, two additional copies of the application
must be sent to:
H.  George Hausch, Ph.D.
Division of Extramural Research
National Institute of Dental Research
Natcher Building, Room 4AN.44F
45 Center Drive, MSC 6402
Bethesda, MD  20892-6402
Telephone:  (301) 594-2372
It is important to emphasize that the F30 program is a training
mechanism and not a research mechanism.  The central issues in review
are [a] the applicant's potential for a productive scientific career,
[b] the role of the sponsor in the research training that is
proposed, [c] the record of the sponsor and the Ph.D. program in
producing active, funded research scientists, and [d] the probability
that the graduate training will enable the fellow to engage in
research with dental, oral and craniofacial relevance.
Applications will be reviewed for completeness and responsiveness to
the PA by NIH staff.  Incomplete or nonresponsive applications will
be returned to the applicant without further consideration.
Remaining applications may be subjected to triage by the NIDR Special
Grants Review Committee, a standing NIH initial review group, to
determine their merit relative to others received in response to the
PA.  The NIDR will withdraw applications judged to be noncompetitive
and notify the applicant.  Applications judged to be competitive will
be evaluated further for scientific and technical merit by the review
Detailed review criteria are listed below:
o  evidence of the applicant's commitment to a career in research
o  the applicant's demonstrated potential for a productive research
o  quality of the applicant's academic record, awards, and honors
o  extent and quality of applicant's previous research and/or
clinical training
Research Training Plan:
o  specificity and clarity of the description of the research skills
and knowledge to be acquired
o  overall coherence and potential of the research training plan to
provide the fellow with individualized supervised experiences that
will foster research skills
o  clarity, completeness, originality, and significance of the goals
of the proposed research training plans
o  adequacy of knowledge of relevant literature and current methods
in the proposed research area
o  adequacy of plans for the protection of human subjects and/or care
of animals, if applicable
o  adequacy of plans to include women and minorities as subjects in
research, if applicable
o  adequacy of plans for training in the responsible conduct of
o  adequacy and relevance of sponsor's academic and research
qualifications and experience in providing guidance to fellows and
o  evidence of the proposed sponsor's understanding of and commitment
to fulfilling the role of sponsor
o  evidence of an understanding of the applicant's research training
needs and a demonstrated ability, on the part of the sponsor, to
assist in meeting these needs
o  adequacy of the sponsor's ongoing research program as a context
for the expected research training
o  evidence that there is an established D.D.S./D.M.D.- Ph.D. program
o  access to facilities and related resources (e.g., equipment,
laboratory space, computer time, subject populations) necessary to
provide the applicant a high-quality training environment
o  strength of the institution's commitment to research training as
demonstrated by ongoing programs, experienced faculty, and, in
particular, commitment to the proposed D.D.S./D.M.D.- Ph.D. student
o  track record of the department and sponsor in training students
who become active researchers
o  track record of the department in training and graduating women
and racial/ethnic minorities
o  strength of the institution's overall research activities
o  strength and specificity of the proposed sponsor's endorsement of
the applicant, including identification of the applicant's strengths
and weaknesses
o  strength and specificity of additional references as well as
adequacy of these reports based on the referee's opportunity to
observe and evaluate the applicant's potential as a research
o  Secondary review will be conducted by the National Advisory Dental
Research Council (NADRC).
Shortly after the initial review meeting, each candidate will be sent
a mailer that includes the IRG recommendation, the priority score,
and the name of a program official in the Division of Extramural
Research, NIDR.  The institute automatically forwards a copy of the
summary statement to the applicant as soon as possible after receipt
from the IRG. Following the second-level review, the institute will
notify each applicant of the final disposition of the application.
Any questions about initial review recommendations and funding
possibilities should be directed to the appropriate institute program
Applications will compete for available funds with all other approved
training and fellowship applications assigned to the NIDR. The
following will be considered in making funding decisions:  quality of
the application as determined by peer review, availability of funds,
program  priority, and balance among types of research training
supported by the NIDR.
An awardee has up to 6 months from the issue date on the award notice
to activate the award.  Under unusual circumstances, an NIH institute
may grant an extension of the activation period upon receipt of a
specific request from the fellow.
Terms and Conditions of Award
Awards are made for full-time efforts to achieve the D.D.S./D.M.D.
and Ph.D.  Fellows are expected to use their time in course studies,
clinical duties, research training, research, and other necessary and
relevant activities in such a way as to optimize their training
experience.  Awardees in academic institutions are not entitled to
vacations as such.  They are, however, entitled to the normal short
student holidays observed by their training institution.  The time
between the spring and fall semester is to be used as an active part
of the training period.
An NRSA may not be held concurrently with another Federally sponsored
fellowship or similar Federal award that provides a stipend or
otherwise duplicates provisions of the NRSA.  An NRSA recipient may,
however, accept concurrent educational remuneration from the
Department of Veterans' Affairs and loans from Federal funds.
No funds may be disbursed until the individual has started training
under the award and an Activation Notice (PHS-416-5) has been
submitted to PHS.  At the end of the total support period, the
individual fellow must submit a Termination Notice (PHS-416-7) to the
NIDR in order to ensure proper documentation of the fellow's records.
Fellowships must be administered in accordance with the current
National Research Service Award Guidelines for Individual Awards and
Institutional Grants, the current PHS Grants Policy Statement, and
any terms and conditions specified on the award notice. The following
policies are noted:
PHS policy is to make available to the public the results and
accomplishments of the activities that it funds.  Therefore, it is
incumbent upon fellows to make results and accomplishments of their
F30 activities available to the public.  There should be no
restrictions on the publication of results in a timely manner.
Publications should acknowledge support from the NIDR, including
grant number.  Except as otherwise provided in the terms and
conditions of the award, the recipient is free to arrange for
copyright without approval when publications, data, or other
copyrightable works are developed in the course of work under a PHS
grant-supported project or activity. Any such copyrighted or
copyrightable works shall be subject to a royalty-free, nonexclusive,
and irrevocable license to the Government to reproduce, publish, or
otherwise use them, and to authorize others to do so for Federal
Government purposes.
The NIH research training and career development programs are
conducted in compliance with applicable laws that provide that no
person shall, on the grounds of race, color, national origin,
handicap, or age, be excluded from participation in, be denied the
benefits of, or be subjected to discrimination under any program or
activity (or, on the basis of sex, with respect to any education
program or activity) receiving Federal assistance.
Written and telephone inquiries concerning this PA are encouraged.
The opportunity to clarify any issue or questions from potential
applicants is welcome.
Direct inquiries on programmatic issues to:
James A. Lipton, DDS, Ph.D.
Division of Extramural Research
National Institute of Dental Research
Natcher Building, Room 4AN-18J
45 Center Drive, MSC 6402
Bethesda, MD  20892-6402
Telephone:  (301) 594-2618 or 594-7710
FAX:  (301) 480-8318
Direct inquiries pertaining to grants management issues to:
Mr. Martin Rubinstein
Division of Extramural Research
National Institute of Dental Research
Natcher Building, Room 4AS-55
45 Center Drive, MSC 6402
Bethesda, MD  20892-6402
Telephone:  (301) 594-4800
FAX:  (301) 480-8303
NRSA awards are made under the authority of Section 487 of the Public
Health Service Act as amended (42 USC 288), and Title 42 of the Code
of Federal Regulations, Part 66. The following Catalog of Federal
Domestic Assistance numbers are applicable to these awards: 93.121,
93.172, 93.173, 93.272, 93.278, 93.282, 93.306, 93.361, 93.398,
93.821, 93.837-93.839, 93.846-93.849, 93.853-93.856, 93.859, 93.862-
93.867, 93.880, 93.894, and 93.929.  This program is not subject to
the intergovernmental review requirements of Executive Order 12372 or
Health Systems Agency review.
The PHS strongly encourages all grant and contract recipients to
provide a smoke-free workplace and promote the non-use of all tobacco
products.  In addition, Public Law 103-227, the Pro- Children Act of
1994, prohibits smoking in certain facilities (or in some cases, any
portion of a facility) in which regular or routing education,
library, day care, health care or early childhood development
services are provided to children.  This is consistent with the PHS
mission to protect and advance the physical and mental health of the
American people.

Return to PA Index

Return to NIH Guide Main Index

Office of Extramural Research (OER) - Home Page Office of Extramural
Research (OER)
  National Institutes of Health (NIH) - Home Page National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
  Department of Health and Human Services (HHS) - Home Page Department of Health
and Human Services (HHS)
  USA.gov - Government Made Easy

Note: For help accessing PDF, RTF, MS Word, Excel, PowerPoint, Audio or Video files, see Help Downloading Files.