Full Text PAR-97-063 PLANNING GRANTS FOR NCI CANCER RESEARCH CENTERS NIH GUIDE, Volume 26, Number 18, May 30, 1997 PA NUMBER: PAR-97-063 P.T. 04 Keywords: Cancer/Carcinogenesis Demography Diagnosis, Medical Disease Prevention+ National Cancer Institute Application Receipt Date: January 7 PURPOSE The Cancer Centers Branch (CCB), Division of Cancer Treatment, Diagnosis, and Centers (DCTDC), of the National Cancer Institute (NCI) invites planning grant applications for the development of Cancer Research Centers in a variety of organizational settings. The purpose is to expand the scientific, geographic and demographic diversity of the Cancer Centers Program of the NCI by encouraging research-oriented organizations to develop the qualities of a strong cancer research center and become competitive for a Cancer Center Support Grant. Cancer center planning strategies may focus on a specific research theme (e.g. diagnosis, therapy, epidemiology) or integrate a broad spectrum of research to include the basic, clinical, prevention and control, and population sciences (i.e., an NCI-designated comprehensive cancer center). All approaches to planning cancer centers are encouraged, as long as they address the six essential features of an NCI Cancer Center (i.e. cancer focus, institutional commitment, organizational capabilities, facilities, center director authority, and interdisciplinary coordination and collaboration) and as long as they take advantage of the full range of the organization's capabilities in cancer research. HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2000," a PHS-led national activity for setting priority areas. This PA, Planning Grants for Cancer Research Centers, is related to the priority area of cancer. Potential applicants may obtain a copy of "Healthy People 2000" (Full Report: Stock No. 017-001-00473-0 or Summary Report: Stock No. 017-001-00473-1) through the Superintendent of Documents, Government Printing Office, Washington DC 20402-9235 (telephone 202/512-1800). ELIGIBILITY REQUIREMENTS Applications may be submitted by domestic for-profit and non-profit organizations, public and private, such as universities, colleges, hospitals, and laboratories units of State and local governments, and eligible agencies of the Federal government. Applications may be from a single institution or several institutions (collaborating institutions or consortia) that do not have a Cancer Center Support Grant (CCSG), is not one of a set of collaborating institutions that make up a CCSG-supported NCI cancer center, or has not been supported by a CCPG or a CCSG in the last three years. Racial/ethnic minority individuals, women, and persons with disabilities are encouraged to apply as principal investigators. MECHANISM OF SUPPORT Support for the planning and development of NCI cancer research centers will be through the National Institutes of Health (NIH) planning grant (P20) mechanism, which the NCI refers to in this PA as the cancer center planning grant (CCPG). CCPGs provide up to $175,000 in direct costs in the first year with cost-of-living increases in future years according to existing NCI policy. Applicants may request up to five (5) years of support. Applicants will be responsible for the execution of all activities supported by this grant. Applications submitted in response to this program announcement will compete with other CCPG applications submitted during the same fiscal year. The time and amount of all CCPG awards will be contingent upon the recommendations of peer reviewers and the availability of funds. Awards will be administered under PHS grants policy as stated in the Public Health Service Grants Policy Statement (rev. 4/94). RESEARCH OBJECTIVES Background: The Cancer Centers Program of the NCI currently supports multidisciplinary cancer research centers in a variety of institutions through the Cancer Centers Support Grant (P30) mechanism). Since the National Cancer Act of 1971, the legislative charge of the Program has been to support cancer centers that perform research in the basic, clinical, prevention and control, and population sciences; that promote and enhance multidisciplinary, interdisciplinary and translational research; and that influence how the results of research are coupled to medical practice in the communities and regions that they serve. While every cancer center does not meet all of these broad expectations (i.e. some are specialized in their research approaches), all cancer centers are organized to take maximum advantage of their research capability and opportunities in such a way that they can have an impact on reducing cancer incidence, mortality and morbidity. Research Goals and Scope: The strength of the NCI's Cancer Centers Program is founded in the diversity of academic, free-standing, and consortial institutions that have become NCI-supported cancer centers. The aim of this initiative is to ensure that the scientific, institutional, geographical and demographic diversity of the Program is maintained and expanded by encouraging new research-oriented organizations to apply for CCPGs and develop the research, leadership and organization capabilities expected of an NCI cancer center. The ultimate goal is to see new institutions become successful in competing for Cancer Center Support Grants and be designated as NCI cancer centers. INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS It is the policy of the NIH that women and members of minority groups and their subpopulations must be included in all NIH-supported biomedical and behavioral research projects involving human subjects, unless clear and compelling rationale and justification is provided that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This policy results from the NIH Revitalization Act of 1993 (Section 4928 of Public Law 103-43). All investigators proposing research involving human subjects should read the "NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research," which have been published in the Federal Register of March 20, 1994 (FR 59 14508-14513) and in the NIH Guide for Grants and Contracts, Volume 23, Number 11, March 18, 1994. APPLICATION PROCEDURES Applications are to be submitted on the grant application form PHS 398 (rev. 5/95). Applications must be received by January 7 each year. Application kits are available at most institutional offices of sponsored research and may be obtained from the Office of Extramural Outreach and Information Resources, 6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone (301) 435-0715, email: [email protected]. The title and number of the announcement must be typed in Section 2 on the face page of the application. The format for submission of a Cancer Center Planning Grant is detailed in NCI guidelines entitled, "Planning Grants for NCI-Supported Cancer Research Centers. These guidelines can be obtained from the Cancer Centers Branch of the NCI (see INQUIRIES section). Submit a signed, typewritten original of the application, and three signed exact photocopies in one package to: DIVISION OF RESEARCH GRANTS NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE, ROOM 1040 MSC 7710 BETHESDA, MD 20892-7710 BETHESDA, MD 20817 (for express/courier service) At the same time of submission, please submit two additional copies of the application to: Ms. Toby Friedberg Division of Extramural Activities National Cancer Institute Executive Plaza North, Room 636 6130 Executive Boulevard Bethesda, MD 20892 Rockville, MD 20852 (for express mail) REVIEW CONSIDERATIONS The review criteria for CCPGs are outlined in the NCI guidelines entitled, "Planning Grants for NCI-Supported Cancer Research Centers. These guidelines can be obtained from the Cancer Centers Branch of the NCI (see INQUIRIES section). AWARD CRITERIA Applications will compete for available funds with all other approved applications. The following will be considered in making funding decisions: quality of the proposed project as determined by peer review; availability of funds; and program priority. INQUIRIES In order to obtain the NCI guidelines for "Planning Grants for NCI- Supported Cancer Research Centers," which are needed to prepare the application in the proper format and which contain the specific criteria for peer review, and for information regarding programmatic issues please contact: Margaret E. Holmes, Ph.D. Division of Cancer Treatment, Diagnosis and Centers National Cancer Institute 6130 Executive Boulevard, Room 502, MSC 7383 Bethesda, MD 20892-7383 Telephone: (301) 496-8531 FAX: (301) 402-0181 Email: [email protected] Written and telephone inquiries about Cancer Center Planning Grants and the Cancer Centers Program in general are encouraged. Direct inquiries regarding fiscal matters to: Ms. Carolyn Mason Grants Administration Branch National Cancer Institute Executive Plaza South, Room 243 Bethesda, MD 20892 Telephone: (301) 496-7800, ext. 259 FAX: (301) 496-8601 email: [email protected] AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal and Domestic Assistance No. 93.397, Cancer Research. Awards are made under the authorization of the Public Health Service Act, Title IV, Part A (Public Law 78-410, as amended, Public Law 99-158, 42 USC 241 and 285) and administered under PHS grants policies and Federal Regulations at 42 CFR Part 52 and 45 CFR Part 74 and 92. This program is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. The PHS strongly encourages all grant and contract recipients to provide a smoke-free workplace and promote the non-use of tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people. .
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