and Human Services (HHS)
EXPIRED
Department
of Health and Human Services
Participating Organizations
National
Institutes of Health (NIH) (http://www.nih.gov)
Components of
Participating Organizations
National
Center for Research Resources (NCRR) (http://www.ncrr.nih.gov)
Title: Shared Instrumentation Grant Program (S10)
Announcement
Type
This is a reissue of PAR-06-093 which
was previously released December 20, 2005.
Update: The following update relating to this announcement has been issued:
NOTICE: Applications submitted in response to this Funding Opportunity Announcement (FOA) for Federal assistance must be submitted electronically through Grants.gov (http://www.grants.gov) using the SF424 Research and Related (R&R) forms and the SF424 (R&R) Application Guide.
APPLICATIONS MAY NOT BE SUBMITTED IN PAPER FORMAT.
This FOA must be read in conjunction with the application guidelines included with this announcement in Grants.gov/Apply for Grants (hereafter called Grants.gov/Apply).
A registration process is necessary before submission and applicants are highly encouraged to start the process at least four weeks prior to the grant submission date. See Section IV.
Program Announcement (PA) Number: PAR-07-105
Catalog of Federal
Domestic Assistance Number(s)
93.389
Key Dates
Release/Posted Date: December 6, 2006
Opening
Date: February 21, 2007 (Earliest
date an application may be submitted to Grants.gov)
Letters of
Intent Receipt Date(s): Not applicable
NOTE: On
time submission requires that applications be successfully submitted to
Grants.gov no later than 5:00pm local time (of the applicant
institution/organization).
Application Submission/Receipt Date: March 21, 2007
Peer Review Date(s): June-July, October-November
Council Review Date(s): October 2007, January 17,
2008
Earliest Anticipated Start Date: April 1, 2008
Additional Information To Be Available Date: Not applicable
Expiration Date: March 22, 2007
Due Dates for E.O. 12372
Not
Applicable
Additional
Overview Content
Executive Summary
Table of Contents
Part I Overview Information
Part II Full Text of Announcement
Section I. Funding Opportunity
Description
1. Research Objectives
Section II. Award Information
1. Mechanism of Support
2. Funds Available
Section III. Eligibility
Information
1. Eligible Applicants
A. Eligible Institutions
B. Eligible Individuals
2. Cost Sharing or Matching
3. Other - Special Eligibility Criteria
Section IV. Application and
Submission Information
1. Request Application Information
2. Content and Form of Application Submission
3. Submission Dates and Times
A. Submission, Review, and
Anticipated Start Dates
1.
Letter of Intent
B. Submitting an Application Electronically
to the NIH
C. Application Processing
4. Intergovernmental Review
5. Funding Restrictions
6. Other Submission Requirements
Section V. Application Review
Information
1. Criteria
2. Review and Selection Process
A. Additional Review Criteria
B. Additional Review Considerations
C. Sharing Research Data
D. Sharing Research Resources
3. Anticipated Announcement and Award Dates
Section VI. Award Administration
Information
1. Award Notices
2. Administrative and National Policy Requirements
A. Cooperative Agreement Terms and Conditions of Award
3. Reporting
Section VII. Agency Contact(s)
1. Scientific/Research Contact(s)
2. Peer Review Contact(s)
3. Financial/Grants Management Contact(s)
Section VIII. Other Information
- Required Federal Citations
Part II
- Full Text of Announcement
Section I. Funding Opportunity Description
1.
Research Objectives
The purpose of this funding
opportunity is to continue the competitive National Center for Research Resources (NCRR) Shared Instrumentation Grant
(SIG) Program initiated in Fiscal Year 1982. Results of the most recent study,
The National Survey of Academic Research Instruments and Instrumentation, published in 1997 identified bioanalytical equipment
of the type provided through this Program as the top most priority. The
objective of the program is to make available to institutions expensive
research instruments that can only be justified on a
shared-use basis and for which meritorious research projects are described.
The SIG Program provides a cost-effective mechanism for groups of NIH-supported
investigators to obtain commercially-available, technologically sophisticated
equipment costing more than $100,000.
This program is designed to provide for the acquisition or updating of expensive shared-use instrumentation not generally available through other NIH mechanisms, such as the regular research project, program project, or center grant programs. Proposals for research on advancing the design or for the development of new instrumentation will not be considered.
Types of instrumentation supported include, but are not limited to, nuclear magnetic resonance systems, electron and confocal microscopes, mass spectrometers, protein and DNA sequencers, biosensors, x-ray diffractometers and cell sorters. Support will not be provided for general purpose equipment or purely instructional equipment, personal computers, personal workstations, printers, and Ethernet interfaces. Proposals for "stand alone" computer systems will only be considered if the instrument is solely dedicated to the research needs of a broad community of NIH-supported investigators.
For purpose of eligibility, a major user group of three or more investigators must be identified. A minimum of three major users must be Principal Investigators on NIH peer reviewed research grants at the time of the application and award. For purposes of this program, research grants are defined as those grants awarded with the following activity codes: P01, R01, U01, R35, and R37.
The application should also show a clear need for the instrumentation by projects supported by multiple NIH peer review research grants (including, but not limited to those listed above) and demonstrate that these projects will require at least 75 percent of the total usage of the instrument. Major users can be individual researchers, or a group of investigators within the same department or from several departments at the applicant institution. NIH extramural awardees from other nearby institutions may also be included.
If the major user group does not require total usage of the instrument, access to the instrument should be made available to other users upon the advice of the internal advisory committee (see below). These users need not be NIH awardees, but priority should be given to NIH-supported scientists engaged in biomedical/behavioral research. To promote cost effectiveness, to encourage optimal sharing among individual investigators, research groups and departments, and to foster a collaborative multidisciplinary environment, the instrument should be integrated into a central core facility, whenever possible.
Each applicant institution must propose a Principal Investigator who can assume administrative/scientific oversight responsibility for the instrumentation requested. This person need not be an NIH grantee but must be affiliated with the applicant institution and registered on the eRA Commons. An internal advisory committee must be named to assist the Principal Investigator in administering the grant and overseeing the responsibility for the instrument. The membership of this committee should be broadly based and include members without conflicts of interest who can resolve disputes if they arise. The Principal Investigator and the advisory committee are responsible for the development of guidelines for:
The Principal Investigator also will be responsible for:
See Section VIII, Other Information - Required Federal
Citations, for policies related to this announcement.
Section
II. Award Information
1.
Mechanism of Support
This funding opportunity will use the S10 (SIG) award mechanism. As an
applicant, you will be solely responsible for planning, directing, and
executing the proposed project. The SIG provides support for expensive
state-of-the-art instrumentation utilized in both basic and clinical research.
Applications are limited to instruments that cost at least $100,000 per
instrument or integrated instrument system. Since the nature and scope of the
instruments that may be requested will vary, it is anticipated that the size of
an award will vary also. There is no upper limit on the cost of the instrument,
but the maximum award is $500,000. If the amount of funds requested does not
cover the total cost of the instrument, the application should describe the
proposed source(s) of funding for the balance of the cost of the instrument.
Documentation of the availability of the remainder of funding, signed by an
appropriate institutional official, must be presented to NCRR prior to issuance
of award. Awards will be made for the direct costs only. The program does not
provide facilities and administrative (F&A) costs or support for
construction or alterations and renovations. Matching funds are not required.
However, commitment of an appropriate level of institutional support to ensure
the associated infrastructure is expected (building alterations, or
renovations, post-award service contracts and technical personnel). Grants will
be awarded for a period of one year and are not renewable. Supplemental
applications will not be accepted.
Applicants proposing purchase of an instrument that the institution is
planning to lease prior to award are urged to consult with their institutional
sponsored projects office regarding applicable NIH policy prior to executing
the leasing agreement. If the leasing agreement was executed more than one
year prior to submission of the SIG application, the applicant must provide
strong justification for the requested Federal funds. Further, the instrument
must be considered state-of-the-art at the time of submission of the SIG
application. Award adjustments may be necessary. Execution of a purchase order
or agreement, making a down payment or other formal commitment to purchase the
equipment prior to award must be in compliance with NIH policy regarding
pre-award cost authority (see most current version of the NIH Grants Policy
Statement). Non-compliance with this policy automatically eliminates an
applicant from eligibility for an award.
2. Funds Available
Although the financial plans of the NCRR provide support for this program,
awards pursuant to this funding opportunity are contingent upon the
availability of funds and the receipt of a sufficient number of meritorious
applications.
The NCRR intends to commit approximately $43 million in FY2008 to fund approximately 125 new awards. The minimum award is $100,000; the maximum award is $500,000. Since the cost of the various instruments will vary, it is anticipated that the size of the award also will vary. The total amount awarded and the number of awards will depend on the funds available for the SIG program. Awards are for one year only. The anticipated start date is April 1, 2008.
Section III. Eligibility Information
1. Eligible Applicants
1.A. Eligible Institutions
You may submit an
application if your institution has any of the following characteristics:
Under the general research support authority of Section 301(a) (3) of the Public Health Service Act, Shared Instrumentation Grant awards are made to public and non-profit domestic institutions only. These institutions include health professional schools, other academic institutions, hospitals, health departments, and research organizations. Note that Federal institutions, foreign institutions, and for-profit institutions are not eligible to apply. A Federal institution is defined by the NIH as a Cabinet-level department or independent agency of the executive branch of the Federal Government or any component organization of such a department or agency.
To be eligible to apply, three or more NIH funded investigators (Principal Investigators of active P01, R01, U01, R35 or R37 research grants) who will be users of the requested instrument must be identified.
1.B. Eligible Individuals
Any individual with the skills, knowledge, and resources necessary to carry out the proposed research as the Project Director/Principal Investigator (PD/PI) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
2. Cost
Sharing or Matching
This program does not require cost sharing as
defined in the current NIH
Grants Policy Statement.
3. Other-Special
Eligibility Criteria
For purpose of
eligibility, a major user group of three or more investigators must be
identified. A minimum of three major users must be Principal Investigators on
NIH peer reviewed research grants at the time of the application and award.
For purposes of this program, research grants are defined as those grants
awarded with the following activity codes: P01, R01, U01, R35, and R37.
Applications will be accepted that request a single, commercially-available instrument or integrated instrument system which costs at least $100,000. There is no restriction on the number of applications an institution can submit to the SIG program each year provided the applications request different types of equipment. However, if two or more applications are submitted for similar equipment (for example, two 600 MHz NMR spectrometers) from the same institution, documentation from a high level institutional official must be provided stating that this is not an unintended duplication, but part of a campus wide institutional plan. An application requesting more than one type of instrumentation (for example, a mass spectrometer and a confocal microscope) will not be considered responsive to this FOA and will be returned without review.
Section IV. Application and Submission Information
To download a SF424 (R&R) Application Package and
SF424 (R&R) Application Guide for completing the SF424 (R&R) forms for
this FOA, link to http://www.grants.gov/Apply/ and follow the directions provided on that Web site.
A one-time registration is required for institutions/organizations at both:
PDs/PIs should work with their institutions/organizations to make sure they are registered in the eRA Commons.
Several additional separate actions are required before an applicant institution/organization can submit an electronic application, as follows:
1) Organizational/Institutional Registration in Grants.gov/Get Started
2) Organizational/Institutional Registration in the eRA Commons
3) Project Director/Principal Investigator (PD/PI) Registration in the NIH eRA Commons: Refer to the NIH eRA Commons System (COM) Users Guide.
Note that if a PD/PI is also an NIH peer-reviewer with an Individual DUNS and CCR registration, that particular DUNS number and CCR registration are for the individual reviewer only. These are different than any DUNS number and CCR registration used by an applicant organization. Individual DUNS and CCR registration should be used only for the purposes of personal reimbursement and should not be used on any grant applications submitted to the Federal Government.
Several of the steps of the registration process could take four weeks or more. Therefore, applicants should immediately check with their business official to determine whether their organization/institution is already registered in both Grants.gov and the Commons. The NIH will accept electronic applications only from organizations that have completed all necessary registrations.
1.
Request Application Information
Applicants must download the SF424 (R&R) application
forms and SF424 (R&R) Application Guide for this FOA through Grants.gov/Apply.
Note: Only the forms package
directly attached to a specific FOA can be used. You will not be able to use
any other SF424 (R&R) forms (e.g., sample forms, forms from another FOA),
although some of the "Attachment" files may be useable for more than
one FOA.
For further assistance, contact GrantsInfo: Telephone 301-710-0267, Email: [email protected].
Telecommunications for the hearing impaired: TTY 301-451-5936.
2. Content and Form of Application Submission
Prepare all applications using the SF424 (R&R) application forms and in accordance with the SF424 (R&R) Application Guide and Special Instructions provided in this FOA (see below) through Grants.gov/APPLY.
The SF424 (R&R) Application Guide is critical to submitting a complete and accurate application to NIH. There are fields within the SF424 (R&R) application components that, although not marked as mandatory, are required by NIH (e.g., the Credential log-in field of the Research & Related Senior/Key Person Profile component must contain the PD/PI’s assigned eRA Commons User ID). Agency-specific instructions for such fields are clearly identified in the Application Guide. For additional information, see Frequently Asked Questions Application Guide, Electronic Submission of Grant Applications.
The SF424 (R&R) application is comprised of data arranged in separate components. Some components are required, others are optional. The forms package associated with this FOA in Grants.gov/APPLY will include all applicable components, required and optional. A completed application in response to this FOA will include the following components:
Required
Components:
SF424 (R&R) (Cover component)
Research & Related Project/Performance Site
Locations
Research & Related Other Project Information
Research & Related Senior/Key Person
PHS398 Cover Page Supplement
PHS398 Checklist
Optional
Components:
PHS398 Cover Letter File
SPECIAL INSTRUCTIONS
SF424 (R&R) Cover Component
11. Descriptive Title of the Applicant’s Project. Enter the type of instrument requested.
13. Proposed Project. Enter start date of 04/01/2008 and end date of 03/31/2009.
16. Estimated Project Funding. Enter the total Federal funds for the requested instrument in line a. This will be the total cost since the award period for the SIG program is one year. If the cost of the instrument is more than $500,000, enter $500,000 on this line, since this is the maximum award under the SIG program. In line b, enter the total cost of the instrument from the quote. If lines a and b are not the same, explain the difference in section 10 Equipment in the Other Project Information component (see below). Enter zero for line c.
SF424 Research & Related Other Project Information
1. Are Human Subjects Involved? Check no.
2. Are Vertebrate Animals Used? Check no.
6. Project Summary/Abstract. The Project Summary/Abstract and Relevance components must be combined as one single document and attached in line 6.
The first and major component of the Project Summary/Abstract is a Project Summary. It is meant to serve as a succinct and accurate description of the proposed work when separated from the application. State the application’s broad, long-term objectives and specific aims, making reference to the health relatedness of the project. Describe concisely the research design and methods for achieving the stated goals. This section should be informative to other persons working in the same or related fields and, insofar as possible, should be understandable to a scientifically or technically literate reader.
The second component of the Project Summary/Abstract is Relevance. Using no more than two or three sentences, describe the relevance of this research to public health. In this section be succinct and use plain language that can be understood by a general, lay audience.
The Project Summary/Abstract must be no longer than 30 lines of text.
7. Project Narrative. If you are submitting an resubmission (Cover Page Item 8) then you should include an Introduction describing the changes that have been made in response to comments in the previous review. This Introduction may not exceed three pages.
Divide the Project Narrative into the following sections that follow the review criteria.
A) Justification of Need
Describe the instrument requested. Inventory similar instruments existing at the applicant institution, neighboring research institutions, or otherwise accessible; describe why they are unavailable or inappropriate for the proposed research. Provide a clear justification why new or updated equipment, including accessories, are needed. Include specific documentation on the current usage and downtime of existing instruments and a realistic estimate of the projected usage for the requested instrument. Such documentation should be expressed as hours of use, setup time, etc., per day or week, not simply as percentage of available time. Be specific and quantitative.
B) Research Projects
Give a brief description of the major users projects. Since the projects have been previously peer reviewed, the project descriptions should be concise and focus on the benefit of the instrument to the research objectives of each user. Sufficient technical detail (preliminary data and/or supplemental information) should be included within the research plan to evaluate whether the instrument is appropriate, would be effectively employed, and would provide advantages over other methods. The need for special features and accessories must be justified. Individual projects that require a specific option or upgrade (e.g., a UV laser) should describe the specific studies that utilize this option. If possible, each user should highlight those publications that demonstrate the user's expertise in using the requested instrumentation. If the number of projects is large and broadly diversified, select out a smaller representative group. For minor users, only include a very brief (one-paragraph) summary of the research related to the need for the instruments. Although there is no overall page limitation, the research projects should be informative and succinct (recommend three pages or less per major user).
C) Summary Table(s)
Use a table to list the names of the users from section B, brief titles of the projects, the NIH grant numbers and the estimated percentage of use. Make a separate table to indicate the users needs for the requested accessories.
D) Technical Expertise
Describe the technical expertise present at the institution to set up, run and maintain the instrument. Specify who will operate the instrument, train new users, ensure that it is operated safely and appropriately maintained.
E) Organizational / Management Plan
Describe the organizational plan to administer the grant. Include how the instrument will be utilized, how requests are made, how time will be allocated among major and minor users and plans for attracting new users. List the names and titles of the members of the local advisory committee to describe a plan for managing access to the instrument if users projects involve human subjects, animals or human of infectious materials.
Submit a specific financial plan for long-term operation and maintenance of the instrument. Explain how the costs to place the instrument in operational order as well as the maintenance, support personnel, and service costs associated with effective use of the instrument will be met.
F) Institutional Commitment
Describe the institutional infrastructure available to support the instrumentation. Provide documentation (e.g., separate letters signed by appropriate institutional officials) specifically describing the required institutional commitment (in dollars) in support of the proposed plan. Those letters must be scanned and uploaded in the Other Attachments section (line 11).
G) Overall Benefit
Explain how the instrument will impact NIH funded research and contribute to the institution’s long- range biomedical research goals.
The entire Project Narrative (Section A-G) must be saved as a single file and attached as item 7 in the Other Project Information component. Although there is no overall page limit, applicants are reminded to be informative yet succinct.
9. Facilities & Other Resources. Not applicable. Do not include an attachment here.
10. Equipment. Describe the instrument requested including manufacturer and model number. The model chosen should be justified by comparing its performance with other available instruments where appropriate. Specific features and any accessories should be justified, both in this section and in the description of research projects. Provide a detailed budget breakdown of the main equipment and accessories requested including tax and import duties, if applicable. An itemized quote from a vendor should be included. The quote must be scanned and combined in a single attachment with the equipment description as part of the item 10 upload. If human or infectious materials, which could create a potential biohazard, are to be analyzed, funds for accessory containment equipment for the instrument may be requested in the budget. In this case, a signed letter from the institutional biosafety committee stating that they have reviewed the proposed containment plan and that the plan adheres to documented biosafety regulations is required in the application. This letter must be scanned and uploaded in the Other Attachments section (line 11).
11. Other Attachments. Both letters from appropriate institutional officials (mentioned in F Institutional Commitment) and letters from the biosafety committee (line 10), if needed, should be attached here. After the application has been submitted, the assigned SRA must be contacted concerning submission of supplemental information.
Senior/Key Person Profile(s) Component
Include profiles for the Principal Investigator, the Major Users, and for the technical person(s) responsible for the maintenance and operation of the instrument. For the Major Users, select Other under Project Role. Then complete the Other Project Role Category by inserting Major User. For technical person(s), select Technician for Project Role field. Follow the instructions in the Application Guide for Additional Senior/Key Person Profile(s) if there are more than 8 major users.
11. Current and Pending Support. This FOA requires current and pending support for the Principal Investigator, each major user and/or technician at the time of application submission. Follow the format provided in Other Support section of the Application Guide (Part III. Section I.H. Other Support).
PHS398 Cover Page Supplement
2. Human Subjects. Check no to both the Clinical Trial and Agency-Defined Phase III Clinical Trial questions.
4. Human Embryonic Stem Cells. Check no.
3.
Submission Dates and Times
See Section IV.3.A for
details.
3.A.
Submission, Review, and Anticipated Start Dates
Opening Date:
February 21, 2007 (Earliest date an application may be
submitted to Grants.gov)
Application Submission/Receipt Date: March 21, 2007
Peer Review Dates: June-July, October-November
Council Review Dates: October 2007, January 2008
Earliest Anticipated Start Date: April 1, 2008
3.A.1. Letter of
Intent
A letter of intent is not required for the funding opportunity.
3.B. Submitting an Application Electronically to the
NIH
To submit an application in response to this FOA, applicants should access this
FOA via http://www.grants.gov/Apply and follow steps 1-4. Note: Applications must only be submitted
electronically. PAPER APPLICATIONS WILL NOT BE ACCEPTED.
3.C.
Application Processing
Applications may be submitted on or after
the opening date and must be successfully received by Grants.gov no
later than 5:00 p.m. local time (of the
applicant institution/organization) on the
application submission/receipt date(s). (See Section IV.3.A. for all dates.) If an application is not submitted by the receipt
date(s) and time, the application may be delayed in the review process or not
reviewed.
Once an application package has been successfully submitted through Grants.gov, any errors have been addressed, and the assembled application has been created in the eRA Commons, the PD/PI and the Authorized Organization Representative/Signing Official (AOR/SO) have two business days to view the application image.
Upon receipt, applications will
be evaluated for completeness by the Center for Scientific Review, NIH.
Incomplete applications will not be reviewed.
There will be an acknowledgement of receipt of
applications from Grants.gov and the Commons. Information related to the
assignment of an application to a Scientific Review Group is also in the Commons.
Note: Since email can be unreliable, it is the responsibility of the applicant to check periodically on their application status in the Commons.
The NIH will not accept any application in response to this FOA that is essentially the same as one currently pending initial merit review unless the applicant withdraws the pending application. The NIH will not accept any application that is essentially the same as one already reviewed. This does not preclude the submission of an application already reviewed with substantial changes, but such application must include an Introduction addressing the previous critique. Note such an application is considered a "resubmission" for the SF424 (R&R).
4. Intergovernmental Review
This initiative is not subject to intergovernmental
review.
5.
Funding Restrictions
All NIH awards are subject to the terms and
conditions, cost principles, and other considerations described in the NIH Grants Policy Statement.
Pre-award Costs are allowable. A grantee may, at
its own risk and without NIH prior approval, incur obligations and expenditures
to cover costs up to 90 days before the beginning date of the initial budget
period of a new or competing renewal award if such costs: are necessary to conduct the project,
and would be allowable under the grant, if awarded, without NIH prior approval.
If specific expenditures would otherwise require prior approval, the grantee
must obtain NIH approval before incurring the cost. NIH prior approval is
required for any costs to be incurred more than 90 days before the beginning
date of the initial budget period of a new award.
The incurrence of pre-award costs in anticipation of a
competing or non-competing award imposes no obligation on NIH either to make
the award or to increase the amount of the approved budget if an award is made
for less than the amount anticipated and is inadequate to cover the pre-award
costs incurred. NIH expects the grantee to be fully aware that pre-award costs
result in borrowing against future support and that such borrowing must not
impair the grantee's ability to accomplish the project objectives in the
approved time frame or in any way adversely affect the conduct of the project.
See the NIH Grants
Policy Statement.
6. Other Submission
Requirements
PD/PI
Credential (e.g., Agency Login)
The NIH requires the PD/PI to fill in his/her Commons User ID in the PROFILE Project Director/Principal Investigator section, Credential log-in field of the Research & Related Senior/Key Person Profile component. The applicant organization must include its DUNS number in its Organization Profile in the eRA Commons. This DUNS number must match the DUNS number provided at CCR registration with Grants.gov. For additional information, see Registration FAQs Important Tips -- Electronic Submission of Grant Applications.
Organizational DUNS
The applicant organization must include its DUNS number in its Organization Profile in the eRA Commons. This DUNS number must match the DUNS number provided at CCR registration with Grants.gov. For additional information, see Frequently Asked Questions Application Guide, Electronic Submission of Grant Applications.
Warning: Please be sure that you observe the direct cost, project period, and page number limitations specified above for this FOA. Application processing may be delayed or the application may be rejected if it does not comply with these requirements.
Section V. Application Review Information
1. Criteria
Only the review
criteria described below will be considered in the review process.
2. Review and
Selection Process
Upon receipt,
applications will be reviewed for responsiveness by the NCRR. Incomplete and/or
non-responsive applications will be returned to the applicant without further
consideration
Applications that are complete and responsive to the FOA will be evaluated for scientific and technical merit by specially convened initial review groups of the CSR in accordance with the review criteria stated below. As part of the initial merit review, all applications will:
In making funding decisions, the NCRR will give consideration to the following:
Review Criteria:
The review committee will
consider the following criteria:
Is the need for the instrument clearly and adequately justified? Is the equipment essential and appropriate?
Does the institution have the technical expertise to make effective use of the requested equipment? How well qualified are the participating investigators or other assigned personnel to operate and maintain the instrument, conduct the projects, and evaluate the research results? How will new users be trained?
How will biosafety procedures be implemented?
Will research with the requested instrument advance the knowledge and understanding of the proposed projects? How would the research project of each major user be enhanced?
Is the plan for the management and maintenance of the requested instrument appropriate? Is the membership of the advisory committee broadly based to oversee the use of the instrument for a wide range of biomedical investigators? How will research time be allocated among the projects? Are the sharing arrangements equitable? If needed, are the policies to manage human subject, animal or biohazardous materials projects adequate? Is the financial plan for long-term operation and maintenance of the instrument reasonable?
What is the evidence of institutional commitment for continued support of the utilization and maintenance of the instrument? Is there appropriate documentation (letters from institutional officials)?
Will the instrument requested benefit the overall research community and
have a significant impact on NIH-funded research?
2.A. Additional Review
Criteria:
Not applicable
2.B.
Additional Review Considerations
Budget: The reasonableness of the proposed budget and the requested
period of support in relation to the proposed research. The priority score
should not be affected by the evaluation of the budget.
2.C.
Sharing Research Data
Not Applicable.
2.D.
Sharing Research Resources
Not applicable.
3.
Anticipated Announcement and Award Dates
Not applicable.
Section
VI. Award Administration Information
1.
Award Notices
After the peer review of the application is completed, the PD/PI will be able
to access his/her Summary Statement (written critique) via the NIH eRA Commons.
Just-in-time information will not be requested for S10
applications.
A formal notification in the form of a Notice of Award
(NoA) will be provided to the applicant organization. The NoA signed by the
grants management officer is the authorizing document. Once all administrative
and programmatic issues have been resolved, the NoA will be generated via email
notification from the awarding component to the grantee business official.
Selection of an application for award is not an
authorization to begin performance. Any costs incurred before receipt of the
NoA are at the recipient's risk. These costs may be reimbursed only to the
extent considered allowable pre-award costs. See Section
IV.5., Funding Restrictions.
2.
Administrative and National Policy Requirements
All NIH grant and cooperative agreement awards include
the NIH Grants Policy Statement as part of the NoA. For these terms of
award, see the NIH
Grants Policy Statement Part II: Terms and Conditions of NIH Grant Awards,
Subpart A: General and Part
II: Terms and Conditions of NIH Grant Awards, Subpart B: Terms and Conditions
for Specific Types of Grants, Grantees, and Activities.
3.
Reporting
Ninety days following the end of the project period, a Final Progress report is
required that describes the instrument purchased, and a list of all users and
description of the value of the instrument to the investigators and to the
institution as a whole. The Final Progress Report instructions are available
at http://www.ncrr.nih.gov/biotech/btforms.asp.
Section
VII. Agency Contacts
We encourage your inquiries concerning this funding
opportunity and welcome the opportunity to answer questions from potential
applicants. Inquiries may fall into three areas: scientific/research, peer
review, and financial or grants management issues:
1. Scientific/Research
Contacts:
Marjorie A. Tingle, Ph.D.
Shared Instrumentation Grant Program
National Center for
Research Resources
6701 Democracy Blvd, Bldg 1, Room 958
MSC 4874
Bethesda, MD 20892-4874 (courier service 20817)
Telephone: (301) 301-435-0772
Fax: (301) 480-3659
Email: [email protected]
2. Peer Review Contacts:
Not
applicable.
3. Financial or Grants
Management Contacts:
Ms. Jenelle D. Wiggins
Office of Grants Management
National Center for
Research Resources
6701 Democracy Blvd. Bldg 1, Room 1038
MSC 4874
Bethesda, MD 20892-4874 (courier service 20817)
Telephone: (301) 435-0843
Fax: (301) 480-3777
Email: [email protected]
Section VIII. Other Information
Required
Federal Citations
NIH Public Access Policy:
NIH-funded investigators are requested to submit to
the NIH manuscript submission (NIHMS) system (http://www.nihms.nih.gov) at
PubMed Central (PMC) an electronic version of the author's final manuscript
upon acceptance for publication, resulting from research supported in whole or
in part with direct costs from NIH. The author's final manuscript is defined as
the final version accepted for journal publication, and includes all
modifications from the publishing peer review process.
NIH is requesting that authors submit manuscripts
resulting from 1) currently funded NIH research projects or 2) previously
supported NIH research projects if they are accepted for publication on or
after May 2, 2005. The NIH Public Access Policy applies to all research grant
and career development award mechanisms, cooperative agreements, contracts,
Institutional and Individual Ruth L. Kirschstein National Research Service
Awards, as well as NIH intramural research studies. The Policy applies to
peer-reviewed, original research publications that have been supported in whole
or in part with direct costs from NIH, but it does not apply to book chapters,
editorials, reviews, or conference proceedings. Publications resulting from
non-NIH-supported research projects should not be submitted.
For more information about the Policy or the
submission process, please visit the NIH Public Access Policy Web site at http://publicaccess.nih.gov/
and view the Policy or other Resources and Tools, including the Authors' Manual.
URLs in NIH Grant Applications or Appendices:
All applications and proposals for NIH funding
must be self-contained within specified page limitations. For publications
listed in the appendix and/or Progress report, internet addresses (URLs) must be used for publicly accessible on-line journal articles. Unless
otherwise specified in this solicitation, Internet addresses (URLs)
should not be used to provide any other information necessary for
the review because reviewers are under no obligation to view the Internet
sites. Furthermore, we caution reviewers that their anonymity may be
compromised when they directly access an Internet site.
Healthy
People 2010:
The Public Health
Service (PHS) is committed to achieving the health promotion and disease
prevention objectives of "Healthy People 2010," a PHS-led national
activity for setting priority areas. This FOA is related to one or more of the
priority areas. Potential applicants may obtain a copy of "Healthy People
2010" at http://www.health.gov/healthypeople.
Authority and
Regulations:
This program is described in
the Catalog of Federal Domestic Assistance at http://www.cfda.gov/ and is not
subject to the intergovernmental review requirements of Executive Order 12372
or Health Systems Agency review. Awards are made under the authorization of
Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241
and 284) and under Federal Regulations 42 CFR Part 52
and 45 CFR Parts 74 and 92. All awards are subject to the terms and conditions,
cost principles, and other considerations described in the NIH
Grants Policy Statement.
The PHS strongly encourages all grant recipients to provide a smoke-free
workplace and discourage the use of all tobacco products. In addition, Public
Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain
facilities (or in some cases, any portion of a facility) in which regular or
routine education, library, day care, health care, or early childhood
development services are provided to children. This is consistent with the PHS
mission to protect and advance the physical and mental health of the American
people.
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
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