NIH GUIDE, Volume 23, Number 18, May 13, 1994

PA NUMBER:  PA-94-067

P.T. 34


  Biomedical Research, Multidiscipl 

National Institutes of Health


The National Institutes of Health (NIH) announces a program for

administrative supplements to research grants to support individuals

with high potential to reenter an active research career after taking

time off to care for children or parents or to attend to other family

responsibilities.  The aim of these supplements is to encourage fully

trained individuals to reenter research careers within the missions

of the program areas of the NIH.  This program will provide

administrative supplements to existing NIH research grants for the

purpose of supporting full-time or part-time research by these

individuals in a program geared to bring their existing research

skills and knowledge up to date.

The NIH recognizes the need to increase the number of women and

minorities and people with disabilities in basic, behavioral, and

clinical science research careers.  Among the reasons for the low

representation of women may be the fact that women bear a majority of

the responsibilities surrounding child and family care.  To address

this issue, this program is designed to offer opportunities to women

and men who have interrupted their research careers to care for

children or parents or to attend to other family responsibilities.

The objective of the program is for those who receive support to

reestablish careers in biomedical or behavioral research.

In 1992 and 1993, the Office of Research on Women's Health sponsored

a research supplement program to promote reentry with a single

application date each year.  The present program announcement

replaces that program with one with an open receipt date and with

review and funding directly by participating Institutes and Centers

(ICs).  Participating ICs are the National Cancer Institute, National

Eye Institute, National Heart, Lung and Blood Institute, National

Institute on Aging, National Institute on Alcohol Abuse and

Alcoholism, National Institute of Allergy and Infectious Diseases,

National Institute of Arthritis and Musculoskeletal and Skin

Diseases, National Institute of Child Health and Human Development,

National Institute of Dental Research, National Institute of Drug

Abuse, National Institute of Environmental Health Sciences, National

Institute of General Medical Sciences, National Institute on Deafness

and Other Communication Disorders, National Center for Human Genome

Research, and National Center for Research Resources.  The National

Institute of Mental Health (PA-94-043) recently announced a similar

reentry supplement program.  The National Institute of Neurological

Disorders and Stroke previously announced a Research Career

Development Award (K17) for scientists reentering the neurological

sciences (NIH Guide, Vol. 21, No. 33, 1992).


The Public Health Service (PHS) is committed to achieving the health

promotion and disease prevention objectives of "Healthy People 2000,"

a PHS-led national activity for setting priority areas.  This program

announcement, Supplements to Promote Reentry into Biomedical and

Behavioral Research Careers, is related to the priority area of

women's health.  Potential applicants may obtain a copy of "Healthy

People 2000" (Full Report:  Stock No. 017-001-00474-1) through the

Superintendent of Documents, Government Printing Office, Washington,

DC 20402-9325 (telephone 202-783-3238).


Grants and Cooperative Agreements:  Only the following active NIH

award mechanisms at domestic institutions are eligible for

Supplements to Promote Reentry into Biomedical and Behavioral

Research Careers:  R01, R10, R18, R24, R35, R37, P01, P40, P41, P50,

P51, P60, U01, U10, and G12. Principal Investigators on such awards

are invited to submit a request for an administrative supplement to

the awarding component of the parent grant to support an eligible

candidate interested in reestablishing a research career.  The parent

grant must have at least two years of support remaining at the time

of the proposed beginning date of the supplemental funding.  The

rationale for this policy is to ensure ample opportunity for the

candidate to develop further her or his research skills.  A maximum

of three years supplemental support can be awarded under this

program.  Usually, a parent grant would support only one

administrative supplement (Research Supplements for Underrepresented

Minorities, Research Supplements to Promote the Recruitment of

Individuals with Disabilities into Biomedical Research Careers, or

Research Supplements to Promote Reentry into Biomedical and

Behavioral Research Careers).  Grants most likely to support more

than a single administrative supplement are multicomponent awards.


Candidates must have a doctoral degree, such as M.D., D.D.S., Ph.D.,

O.D., D.V.M., or equivalent, and at least two years of post-doctoral

research experience and must have had sufficient prior research

experience to qualify for a faculty appointment at the  assistant

professor or equivalent level.  Candidates who have begun the reentry

process through a fellowship or similar mechanism are not eligible

for this program.

The following general guidelines will be applied by the individual

ICs.  In general, the duration of the career interruption should be

for at least two years and no more than eight years.  Examples of

qualifying interruptions would include starting and/or raising a

family, an incapacitating illness or injury of the candidate, the

spouse, partner, or a member of the immediate family; relocation to

accommodate a spouse, partner, or other close family member; pursuit

of non-research endeavors that would permit earlier retirement of

debt incurred in obtaining a doctoral degree; and military service.

The program is not intended to support graduate or postdoctoral

training and is not intended to support career changes from non-

research to research careers for individuals without prior research

training.   Generally, at the time of application, a candidate may

not be engaged in paid research activities for more than 25 percent



In all cases, the proposed research must be directly related to the

funded approved ongoing research of the parent grant or cooperative

agreement.  The individual supported under this supplemental award,

hereafter called the reentry candidate, must be afforded the

opportunity to act as a full participant in the research project and

must be given an opportunity to update and enhance her or his

research capabilities.  This will allow the candidate to begin the

process of establishing or re-establishing a career as an

independent, competitive research investigator. Supplemental awards

will be consistent with the goals of strengthening the existing

research program and with the overall programmatic balance and

priorities of the funding program of the NIH.  Awards will be made

according to the policies and provisions stated in this announcement

and in the PHS Grants Policy Statement (rev. 10/90).

Administrative supplements (S1) provided under this program may be

for either part-time or full-time support for the candidate, and all

supported time is to be spent updating and enhancing research skills.

Proposed part-time appointments may not be less than 50 percent

effort per week.

Supplemental awards may be made for up to three years and may not

exceed $50,000 in direct costs per year.  A maximum of $40,000 may be

requested for the combination of full time salary and fringe benefits

for the reentry candidate.  The amount of salary requested must be

consistent with the policies of the grantee institution for

individuals occupying similar positions and must be related to the

percent effort requested for the supplement and the number of months

requested for the supplement.  An additional amount up to $10,000 may

be requested for supplies, domestic travel, and publication costs

relevant to the proposed research.  Equipment may not be purchased as

a part of this supplement without justification and specific prior

approval of the NIH.

The decision to fund a supplement will take six to eight weeks from

the time the necessary information is received by the awarding ICD.

During the first budget period, funds will be provided as an

administrative supplement to the parent grant.  In subsequent years,

continued funding for the supplement is contingent on funding of the

parent grant and can not extend beyond the current competitive

segment of the parent grant.  A decision may be made to pay, but, in

fact, at the end or beginning of a year, no funds may be available.


A request for a supplement may be made at any time during the funding

year, providing there will be two full years of funding remaining for

the parent grant at the time of funding.  In making requests, the

grantee institution, on behalf of the Principal Investigators, should

submit the request for supplemental funds directly to awarding

component that supports the parent grant.  The request is NOT to be

submitted to the NIH Division of Research Grants.  Principal

Investigators are encouraged to obtain the address for submission

from the NIH program administrator on the parent grant.

The request for a supplemental award must include the following:

1.  A complete face page (with appropriate signatures) from grant

application form PHS 398 (rev. 9/91), including the title and grant

number of the parent grant and "Reentry Supplement" on line 1

2.  A brief, three- or four-page description, prepared by the

Principal Investigator of the parent grant, that includes:

a.  A summary or abstract of the funded grant or project

b.  A description of the research proposed for the candidate

c.  How the supplement will expand and foster the independent

research capabilities of the candidate

d.  How the proposed research relates to the specific research goals

and objectives of the parent grant

e.  A description of the scope and nature of the mentoring

relationship between the Principal Investigator and the candidate

3.  A brief description, prepared by the candidate, that includes:

a.  research objectives and career goals

b.  length of and reason for career hiatus

c.  description of how the candidate has kept current or attempted to

keep current in her/his field

d.  identification of steps taken toward reentry, (if any, such as

attending scientific meetings)

4.  A biographical sketch of the candidate that includes:

a.  curriculum vitae

b.  social security number

c.  citizenship status

d.  publications

e.  other evidence of scientific achievement.

5.  A proposed budget entered on budget pages from the grant

application form PHS 398 (rev. 9/91), related to the percent effort

for the research proposed for the reentry candidate during the first

and future budget period(s) (The amount requested for the supplement

must coincide with the current period of support.  Thus, if the

initial budget period requested is less than 12 months, the budget

must be prorated accordingly.)

6.  Documentation, if applicable, that the proposed research is

approved by the Institutional Animal Care and Use Committee (IACUC)

or human subjects Institutional Review Board (IRB) of the grantee


7.  Under unusual circumstances in which the applicant and mentor

would be at a site other than the grantee institution, an

appropriately signed letter from the institution where the research

is to be conducted must also be submitted.

The request must be signed by the Principal Investigator, the reentry

candidate, and the appropriate institution business official.


The program staff of the individual ICDs will review requests for

supplements using the following general criteria:

o  the qualifications of the reentry candidate, including career

goals, prior research training, research potential, and any relevant


o  the plan for the proposed research experience in the supplemental

request and its relationship to the parent grant

o  evidence from the Principal Investigator that the experience will

enhance the research potential, knowledge, and/or skills of the

reentry candidate

o  evidence from the Principal Investigator that the activities of

the reentry candidate are an integral part of the project

o  evidence of effort by the reentry candidate to initiate the

reentry process, such as attending scientific meetings, keeping

current with journals

o  evidence that proposed research will achieve the stated objectives

of the reentry supplements

In noncompeting continuation applications, the progress report for

the reentry supplement should be clearly delineated from the progress

report for the parent grant.  The progress report should include

information about the research activities supported by the

supplement, even if support for future years is not requested.  Since

these applications will undergo administrative review, summary

statements will not be produced.  This is consistent with NIH

practice for other similar programs, such as those referenced in the

ELIGIBILITY REQUIREMENTS section of this program announcement.


For general information about the reentry supplements, candidates and

Principal Investigators should contact the program official of the

appropriate awarding Institute or Center.  Candidates who have not

yet made contact with a Principal Investigator are encouraged to

contact the program official whose institute or center is specific to

the research interest.  To discuss business aspects of the parent

grant or the supplement, Principal Investigators should contact their

grants management official.  Program officials and grants management

contacts and the respective awarding institutes or centers are listed


Toby Friedberg

National Cancer Institute

Executive Plaza North, Room 636

Bethesda, MD  20892

Telephone:  (301) 496-3428

FAX:  (301) 402-0275

Ralph J. Helmsen, Ph.D.

National Eye Institute

Executive Plaza South, Suite 350

Bethesda, MD  20892

Telephone:  (301) 496-5301

FAX:  (301) 402-0528

Ronald S. Geller, Ph.D.

National Heart, Lung, and Blood Institute

Westwood Building, Room 7A17

Bethesda, MD  20892

Telephone:  (301) 594-7454

FAX:  (301) 594-7424

Robin Barr or D. Phil. or Joseph Ellis

National Institute on Aging

7201 Wisconsin Avenue, Room 218

Bethesda, MD  20892

Telephone:  (301) 496-9322

FAX:  (301) 402-2945

Helen Chao, Ph.D. or Linda Hilley

National Institute on Alcohol Abuse and Alcoholism

Willco Building, Suite 402

6000 Executive Boulevard

Rockville, MD  20892-7003

Telephone:  (301) 443-2530 or (301) 443-4703

FAX:  (301) 594-0673

Milton Hernandez, Ph.D.

National Institute of Allergy and Infectious Disease

Solar Building, Room 4C10

Bethesda, MD  20892

Telephone:  (301) 496-7291

FAX:  (301) 402-0369

Julia Freeman, Ph.D.

National Institute of Arthritis and Musculoskeletal and Skin Disease

Westwood Building, Room 403

Bethesda, MD  20892

Telephone:  (301) 594-9961

FAX:  (301) 594-9673

Hildegard Topper or Donald Clark

National Institute of Child Health and Human Development

Building 31, Room 2A03

Bethesda, MD  20892

Telephone:  (301) 496-0104 or (301) 496-5001

FAX:  (301) 402-1104

Patricia S. Bryant, Ph.D. or Theresa Ringler

National Institute of Dental Research

Westwood Building, Room 509

Bethesda, MD  20892

Telephone:  (301) 594-7641 or (301) 594-7629

FAX:  (301) 594-9720

Eleanor Friedenberg, Program Official

National Institute on Drug Abuse

5600 Fishers Lane, Room 10-42

Rockville, MD  20857

Telephone:  (301) 443-2755

FAX:  (301) 443-0538

Anne P. Sassaman, Ph.D. or Dave Mineo

National Institute of Environmental Health Sciences

P.O. Box 12233

Research Triangle Park, NC  27709

Telephone:  (919) 541-7723 or (919) 541-7628

FAX:  (919) 541-2843

Anthony A. Rene, Ph.D. or Carol Tippery

National Institute of General Medical Sciences

Westwood Building, Room 925

Bethesda, MD  20892

Telephone:  (301) 594-7706 or (301) 594-7813

FAX:  (301) 594-7701

Earleen F. Elkins, Ph.D.

National Institute on Deafness and Other Communication Disorders

Executive Plaza South, Room 400C

Rockville, MD  20892

Telephone:  (301) 496-8693

FAX:  (301) 402-6250

Jane Peterson, Ph.D.

National Center for Human Genome Research

Building 38A, Room 610

Bethesda, MD  20892

Telephone:  (301) 496-7531

FAX:  (301) 480-2770

Louise E. Ramm, Ph.D. or Lacey J. Durham

National Center for Research Resources

Westwood Building, Room 854

Bethesda, MD  20892

Telephone:  (301) 594-7906 or (301) 594-7955

FAX:  (301) 594-9121


Supplemental awards will be made under authorities applicable to the

parent grant and administered under PHS grants policies and Federal

Regulations 42 CFR 52 and 45 CFR Parts 74 and 92.  This program is

not subject to the intergovernmental review requirements of Executive

Order 12372 or Health Systems Agency review.


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