EXPIRED
SCIENCE EDUCATION DRUG ABUSE PARTNERSHIP AWARD RELEASE DATE: March 4, 2002 PA NUMBER: PA-02-070 (This PA has been replaced, see PAR-05-105) EXPIRATION DATE: March 30, 2005, unless reissued. National Institute on Drug Abuse (NIDA) (www.nida.nih.gov) THIS PROGRAM ANNOUNCEMENT (PA) CONTAINS THE FOLLOWING INFORMATION o Purpose of the PA o Research Objectives o Mechanism of Support o Eligible Institutions o Individuals Eligible to Become Principal Investigators o Where to send Inquiries o Submitting an Application o Peer Review Process o Review Criteria o Award Criteria o Required Federal Citations PURPOSE OF THIS PA This PA will replace, in its entirety, the Science Education Drug Abuse Partnership Award (SEDAPA), PAR-99-076, published in the NIH Guide March 23, 1999. The purpose of the SEDAPA Program is to fund the development and evaluation of innovative model programs and materials for enhancing knowledge and understanding of neuroscience and the biology of drug abuse and addiction among K-12 students, the general public, health care practitioners, and other groups. The award provides support for the formation of partnerships between scientists and educators, media experts, community leaders, and other interested organizations for the development and evaluation of programs and materials that will enhance knowledge and understanding of science related to drug abuse. The intended focus is on topics not well addressed in existing efforts by educational, community, or media activities. RESEARCH OBJECTIVES In recent years there has been increasing awareness of the need to improve efforts in science education in order to maintain U.S. competitiveness and meet future demands in the international technology marketplace. Furthermore, in order for NIH to fulfill its mission, there is a need to ensure that adequate numbers of students are entering science education tracks and eventually pursuing careers in biomedical sciences. It is also important to the mission of NIH that other groups, such as the general public, health care workers, etc. are scientifically literate. This science literacy should not only include basic science knowledge, but also an understanding of the process of biomedical research and an ability to evaluate the quality of research studies that are reported in the media. It is particularly important to the National Institute on Drug Abuse (NIDA) that all members of society understand the role of science, biology, and technology as they relate to neuroscience, behavioral science, and drug abuse and addiction research. There is a lack of public understanding of behaviors that increase the risk for drug abuse, the use of animals in drug abuse related behavioral and biomedical research, and the necessity for basic research to make progress toward improving health. Furthermore, there is a substantial misunderstanding about the nature of addiction as a biologically based brain disorder. To address all of these issues, it is imperative that efforts be made to educate our Nation"s school children, the general public, health care workers, members of the judicial system, the media, and other groups about the science of addiction. Description of the Program. To address the above issues, NIDA is continuing the SEDAPA Program. To address the goals of the SEDAPA Program, proposed science education projects should be developed for one or more of the following groups: 1) students and teachers at the kindergarten through 12th grade levels, 2) the general public, 3) health care practitioners, 4) members of the judicial system, 5) members of the media, and 6) other groups that have a need to be scientifically literate. Programs aimed at school children should convey the scientific process in a way which makes learning science fun and interesting for the students and which captures their enthusiasm for science. Programs aimed at other groups should be directed to increasing their knowledge of scientific terms, concepts, reasoning, and ability to understand scientific public policy issues. Regardless of the intended audience, all projects must involve a partnership between scientists and educators, media experts, community leaders, or other interested organizations. All projects must also enhance knowledge and understanding of science related to drug abuse. To gain maximum benefit from the program, funding priority will be given to projects that are innovative, that do not duplicate existing programs, that have the potential to be replicated for widespread use, and that build on existing science education programs whenever possible. Funding will not be provided to maintain ongoing programs. Programs which support science education for the special needs of underrepresented groups are encouraged. Programmatic activities must propose to increase science literacy and understanding among one or more of the groups listed above. These activities must focus on topics not well addressed through existing efforts by educational, community, or media activities in the geographic area(s) which the program will reach. Wherever relevant and possible, activities must focus on conveying the importance of the responsible use of animals in research. Activities may include, but are not limited to, the following types: o Development of innovative curricula using state-of-the-art technology. o Development of and/or presentation of media programs on the science of drug abuse and addiction. These may include television, radio, motion pictures (including videotape and videodisc), newspaper articles, magazine articles, books, experiments, computer software, CD-ROMs, Internet sites, or other written, electronic, or audiovisual presentations designed to educate about the biology of drug abuse and addiction. o Development of programs in settings designed to educate the public about the biology of drug abuse and addiction. These may be in museums, shopping centers, public buildings, schools, science fairs, or any other suitable places which are open to all or to a segment of the public. o Provision of training, resources, and support for scientists to speak to students, the general public, teachers, parents, health care practitioners, the media or other audiences, such as at PTAs, in classrooms, at workshops for teachers, the media, parents or students, etc. o Development of programs to provide innovative mentorships for students wishing to learn more about science. This activity may be in formal school settings or other community settings. The activity may provide for qualified persons who serve as teachers, as resource persons, or as consultants. Such activities might include working with gifted and talented programs or setting university-based programs for high school students with local school systems. The description of the program must contain the following elements: o Specific goals to be achieved and their relevance to the science of drug abuse and addiction. o Activities to be completed, with discussion of how these activities can accomplish the stated goals. o A statement of why this is a model program or innovative project. o For those projects that focus on K-12 science education, a statement of how the project incorporates the National Science Education Standards and how the project will be incorporated into the classroom. A copy of the National Science Education Standards is available on the World Wide Web at http://www.nap.edu/readingroom/books/nses/. o A clear demonstration of an education and scientific partnership(s) with a description of the nature and extent of partnerships and collaborations to be developed (or, for those already established, plans for expansion or modification), and the roles of key participants in the planning and conduct of the project. Documentation of the interest and commitment of partnership members to the project must be provided. o The administrative plan to organize and manage the overall project and the timetable for the various tasks and activities for the entire project period requested. o Plans for how materials will be disseminated to a broad audience or how model programs may be replicated, including to underrepresented groups in science, such as minorities and women. o Plans for continuation of the project after the grant period has ended. o Plans for assessments/evaluations for determining if the project is successful in achieving its objectives. Descriptions of both formative and summative evaluations and plans to modify the project according to evaluation results are to be included. o Evidence of the applicant institution"s commitment to the SEDAPA Program, including a discussion of: 1) the incentives that would be offered to individuals who elect to participate, and 2) institutional resources that would be devoted to the program. Such incentives might include the awarding of sabbaticals, time released from other duties, or special recognition to individuals to permit them to participate in the program. Institutional resources might include office and workshop space, computer facilities, and administrative and technical services. o A statement of the applicant institution"s capabilities and experiences which are relevant to the stated goals. o Include names and qualifications of all relevant personnel, with biosketch forms completed. o Identification of scientists and educational experts who would participate in the development or delivery of the program and a description of how suitable people for these tasks will be located and recruited for the program. Biosketches for identified persons should be provided. Types of scientists might include neuroscientists, pharmacologists, physiologists, psychologists, chemists, biologists, clinicians, sociologists, and epidemiologists. o Letters stating their commitment to the project from agencies, groups, or persons whose cooperation is important to the achievement of the stated purpose, such as school officials, members of museum boards, television station directors, newspaper or magazine editors, or members of relevant community groups. These should be in the appendix. MECHANISM OF SUPPORT This PA will use the NIH education (R25) award mechanism. As an applicant, you will be solely responsible for planning, directing, and executing the proposed project. Applications may not exceed four years and requested annual direct costs may not exceed $250,000. Facilities and administrative (F&A) costs will be reimbursed at eight percent of total allowable direct costs. Conditions of Award All publications, audiovisual materials and other products resulting from SEDAPA activities supported entirely or in substantial part by NIH/NIDA should include the following or comparable acknowledgement of support: "This project was supported by a Science Education Drug Abuse Partnership Award from the National Institute on Drug Abuse, National Institutes of Health. Its content is solely the responsibility of the authors and does not necessarily represent the official views of NIDA or NIH." An annual progress report must be filed with the Grants Management Office, NIDA, and a final report is due within 90 days of the end of the project period. Reports should summarize the goals, methods, and results of the activity undertaken. Each report should be accompanied by at least two copies of any materials intended for dissemination that were developed through the SEDAPA Program. Any products derived from the project activity must be publicized and must be freely available in the public domain. Products may be distributed under a cost recovery system. Any project funded under the SEDAPA Program may not be used to endorse or publicize any profit-making activities. ELIGIBLE INSTITUTIONS You may submit an application if your institution has any of the following characteristics: o Domestic organization with a scientific and/or education mission o For-profit or non-profit organizations o Public or private institutions, such as universities, colleges, hospitals, professional societies, museums, media producers, private foundations and industries, and research laboratories o Units of State and local governments o Eligible agencies of the Federal government o Faith-based organizations INDIVIDUALS ELIGIBLE TO BECOME PRINCIPAL INVESTIGATORS Any individual with the skills, knowledge, and resources necessary to carry out the proposed research is invited to work with their institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. WHERE TO SEND INQUIRIES We encourage your inquiries concerning this PA and welcome the opportunity to answer questions from potential applicants. Inquiries may fall into three areas: scientific/research, peer review, and financial or grants management issues: o Direct your questions about scientific/research issues to: Cathrine A. Sasek, Ph.D. Office of Science Policy and Communications Science Policy Branch National Institute on Drug Abuse 6001 Executive Blvd. Room 5226, MSC 9591 Bethesda, MD 20892-9591 Telephone: (301) 443-6071 FAX: 301-443-6277 E-mail: [email protected] o Direct your questions about financial or grants management matters to: Gary Fleming, J.D., M.A. Grants Management Branch National Institute on Drug Abuse 6001 Executive Blvd., Room 3131, MSC 9541 Bethesda, MD 20892-9541 FAX: (301) 594-6847 E-mail: [email protected] o Direct your questions about peer review issues to: Teresa Levitin, Ph.D. Office of Extramural Affairs 6001 Executive Blvd., Room 3158, MSC 9547 Bethesda, MD 20892-9547 Telephone: (301) 443-2755 FAX: 301-443-0538 E-mail: [email protected] SUBMITTING AN APPLICATION Applications must be prepared using the PHS 398 research grant application instructions and forms (rev. 5/2001). The PHS 398 is available at http://grants.nih.gov/grants/funding/phs398/phs398.html in an interactive format. For further assistance contact GrantsInfo, Telephone (301) 710-0267, Email: [email protected]. APPLICATION RECEIPT DATES: Applications submitted in response to this program announcement will be accepted at the standard application deadlines, which are available at http://grants.nih.gov/grants/dates.htm. Application deadlines are also indicated in the PHS 398 application kit. SENDING AN APPLICATION TO THE NIH: Submit a signed, typewritten original of the application, including the checklist, and five signed photocopies in one package to: Center for Scientific Review National Institutes of Health 6701 Rockledge Drive, Room 1040, MSC 7710 Bethesda, MD 20892-7710 Bethesda, MD 20817 (for express/courier service) APPLICATION PROCESSING: Applications must be received by or mailed before the receipt dates described at http://grants.nih.gov/grants/funding/submissionschedule.htm. The CSR will not accept any application in response to this PA that is essentially the same as one currently pending initial review unless the applicant withdraws the pending application. The CSR will not accept any application that is essentially the same as one already reviewed. This does not preclude the submission of a substantial revision of an application already reviewed, but such application must include an Introduction addressing the previous critique. PEER REVIEW PROCESS Applications submitted for this PA will be assigned on the basis of established PHS referral guidelines. An appropriate scientific review group convened in accordance with the standard NIH peer review procedures (http://www.csr.nih.gov/refrev.htm) will evaluate applications for scientific and technical merit. As part of the initial merit review, all applications will: o Receive a written critique o Undergo a selection process in which only those applications deemed to have the highest scientific merit, generally the top half of applications under review, will be discussed and assigned a priority score o Receive a second level review by the National Advisory Council on Drug Abuse REVIEW CRITERIA The goals of NIH-supported research are to advance our understanding of biological systems, improve the control of disease, and enhance health. In the written comments, reviewers will be asked to discuss the following aspects of your application in order to judge the likelihood that the proposed research will have a substantial impact on the pursuit of these goals: o Significance o Approach o Innovation o Personnel o Environment As stated above, the purpose of the SEDAPA Program is to fund the development of innovative model programs and materials for enhancing knowledge and understanding of neuroscience and the biology of drug abuse and addiction among K-12 students, the general public, health care practitioners, and other groups. In the written comments, reviewers will be asked to discuss the following aspects of the application in order to judge the likelihood that the proposed project will have a substantial impact on the pursuit of the program"s goals. Each of these criteria will be addressed and considered in assigning the overall score, weighting them as appropriate for each application. (1) SIGNIFICANCE: Does the project meet relevant science education goals? Does the project address currently unmet needs? How will the proposed project advance science and drug abuse education and literacy? Does the project have the potential for widespread dissemination or impact? Does the project have relevance to the science of drug abuse and addiction? (2) APPROACH: Are the conceptual framework, design, methods, and analyses adequately developed, well integrated, and appropriate to the aims of the project? Is the evaluation well developed and able to measure the impact of the project? Is the project feasible? Does the project address the goals of the SEDAPA Program? Are the National Science Education Standards addressed for those projects that focus on K-12 education? Is the program likely to be continued after the grant funding ends? How well developed and feasible are the dissemination plans? What are the administrative plans and timetable? (3) INNOVATION: Does the project employ novel concepts, approaches, or methods? Are the aims original and innovative? Does the project focus on topics not well addressed through existing efforts by educational, community, or media activities in the geographic area(s) which the program will reach? (4) PERSONNEL: Are the personnel appropriately trained and well suited to carry out this project? Is the proposed project appropriate to the experience level of the key personnel and other participants (if any)? Are all appropriate scientific and education experts represented? (5) ENVIRONMENT: Does the environment in which the project will be done contribute to the probability of success? Have appropriate scientific- educational partnerships been formed? Is there adequate institutional commitment from partnership members? Does the proposed project take advantage of unique features of the educational or scientific environment or employ useful collaborative arrangements? Is there evidence of institutional support? Are resources adequate to conduct and complete the project? ADDITIONAL REVIEW CRITERIA: In addition to the above criteria, your application will also be reviewed with respect to the following: PROTECTIONS: The adequacy of the proposed protection for humans, animals, or the environment, to the extent they may be adversely affected by the project proposed in the application. INCLUSION: The adequacy of plans to include subjects from both genders, all racial and ethnic groups (and subgroups), and children as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects will also be evaluated. (See Inclusion Criteria included in the section on Federal Citations, below) BUDGET: The reasonableness of the proposed budget and the requested period of support in relation to the proposed research. AWARD CRITERIA Applications submitted in response to a PA will compete for available funds with all other recommended applications. The following will be considered in making funding decisions: o Scientific merit of the proposed project as determined by peer review o Availability of funds o Relevance to program priorities REQUIRED FEDERAL CITATIONS MONITORING PLAN AND DATA SAFETY AND MONITORING BOARD: Research components involving Phase I and II clinical trials must include provisions for assessment of patient eligibility and status, rigorous data management, quality assurance, and auditing procedures. In addition, it is NIH policy that all clinical trials require data and safety monitoring, with the method and degree of monitoring being commensurate with the risks (NIH Policy for Data Safety and Monitoring, NIH Guide for Grants and Contracts, June 12, 1998: http://grants.nih.gov/grants/guide/notice-files/not98-084.html). INCLUSION OF WOMEN AND MINORITIES IN CLINICAL RESEARCH: It is the policy of the NIH that women and members of minority groups and their sub-populations must be included in all NIH-supported clinical research projects unless a clear and compelling justification is provided indicating that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This policy results from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43). All investigators proposing clinical research should read the AMENDMENT "NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research - Amended, October, 2001," published in the NIH Guide for Grants and Contracts on October 9, 2001 (http://grants.nih.gov/grants/guide/notice- files/NOT-OD-02-001.html), a complete copy of the updated Guidelines are available at http://grants.nih.gov/grants/funding/women_min/guidelines_amended_10_2001.htm. The amended policy incorporates: the use of an NIH definition of clinical research, updated racial and ethnic categories in compliance with the new OMB standards, clarification of language governing NIH-defined Phase III clinical trials consistent with the new PHS Form 398, and updated roles and responsibilities of NIH staff and the extramural community. The policy continues to require for all NIH-defined Phase III clinical trials that: a) all applications or proposals and/or protocols must provide a description of plans to conduct analyses, as appropriate, to address differences by sex/gender and/or racial/ethnic groups, including subgroups if applicable, and b) investigators must report annual accrual and progress in conducting analyses, as appropriate, by sex/gender and/or racial/ethnic group differences. INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS: The NIH maintains a policy that children (i.e., individuals under the age of 21) must be included in all human subjects research, conducted or supported by the NIH, unless there are scientific and ethical reasons not to include them. This policy applies to all initial (Type 1) applications submitted for receipt dates after October 1, 1998. All investigators proposing research involving human subjects should read the "NIH Policy and Guidelines" on the inclusion of children as participants in research involving human subjects that is available at http://grants.nih.gov/grants/funding/children/children.htm. REQUIRED EDUCATION ON THE PROTECTION OF HUMAN SUBJECT PARTICIPANTS: NIH policy requires education on the protection of human subject participants for all investigators submitting NIH proposals for research involving human subjects. You will find this policy announcement in the NIH Guide for Grants and Contracts Announcement, dated June 5, 2000, at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-039.html. HUMAN EMBRYONIC STEM CELLS (hESC): Criteria for federal funding of research on hESCs can be found at http://grants.nih.gov/grants/stem_cells.htm and at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-005.html. Only research using hESC lines that are registered in the NIH Human Embryonic Stem Cell Registry will be eligible for Federal funding (see http://escr.nih.gov). It is the responsibility of the applicant to provide the official NIH identifier(s)for the hESC line(s)to be used in the proposed research. Applications that do not provide this information will be returned without review. PUBLIC ACCESS TO RESEARCH DATA THROUGH THE FREEDOM OF INFORMATION ACT: The Office of Management and Budget (OMB) Circular A-110 has been revised to provide public access to research data through the Freedom of Information Act (FOIA) under some circumstances. Data that are (1) first produced in a project that is supported in whole or in part with Federal funds and (2) cited publicly and officially by a Federal agency in support of an action that has the force and effect of law (i.e., a regulation) may be accessed through FOIA. It is important for applicants to understand the basic scope of this amendment. NIH has provided guidance at http://grants.nih.gov/grants/policy/a110/a110_guidance_dec1999.htm. Applicants may wish to place data collected under this PA in a public archive, which can provide protections for the data and manage the distribution for an indefinite period of time. If so, the application should include a description of the archiving plan in the study design and include information about this in the budget justification section of the application. In addition, applicants should think about how to structure informed consent statements and other human subjects procedures given the potential for wider use of data collected under this award. URLs IN NIH GRANT APPLICATIONS OR APPENDICES: All applications and proposals for NIH funding must be self-contained within specified page limitations. Unless otherwise specified in an NIH solicitation, Internet addresses (URLs) should not be used to provide information necessary to the review because reviewers are under no obligation to view the Internet sites. Furthermore, we caution reviewers that their anonymity may be compromised when they directly access an Internet site. HEALTHY PEOPLE 2010: The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010," a PHS-led national activity for setting priority areas. This PA is related to one or more of the priority areas. Potential applicants may obtain a copy of "Healthy People 2010" at http://www.health.gov/healthypeople. AUTHORITY AND REGULATIONS: This program is described in the Catalog of Federal Domestic Assistance No. 93.279, and is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. Awards are made under authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and administered under NIH grants policies described at http://grants.nih.gov/grants/policy/policy.htm and under Federal Regulations 42 CFR 52 and 45 CFR Parts 74 and 92. The PHS strongly encourages all grant recipients to provide a smoke-free workplace and discourage the use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care, or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people.
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