and Human Services (HHS)
EXPIRED
PHYSICAL ACTIVITY AND OBESITY ACROSS CHRONIC DISEASES
Release Date: November 15, 2000
PA NUMBER: PA-01-017
National Institute of Diabetes and Digestive and Kidney Diseases
http://www.niddk.nih.gov/
National Cancer Institute
http://www.nci.nih.gov/
National Heart, Lung, and Blood Institute
http://www.nhlbi.nih.gov/
National Institute on Aging
http://www.nih.gov/nia/
National Institute of Arthritis and Musculoskeletal and Skin Diseases
http://www.nih.gov/niams/
National Institute of Child Health and Human Development
http://www.nichd.nih.gov/
National Institute of Nursing Research
http://www.ninr.nih.gov/
THIS PROGRAM ANNOUNCEMENT (PA) USES "MODULAR GRANT" AND "JUST-IN-TIME"
CONCEPTS. THIS PA INCLUDES DETAILED MODIFICATIONS TO STANDARD
APPLICATION INSTRUCTIONS THAT MUST BE USED WHEN PREPARING AN
APPLICATION IN RESPONSE TO THIS PA.
This Program Announcement is part of a trans-NIH Obesity Initiative,
which also includes approaches to obesity prevention and the
neuroendocrinology of obesity. The above-named Institutes invite
applications from investigators for research studies that will address
the relationship between physical activity and obesity. Three general
areas of research are encouraged: (1) studies (including observational
and prospective) examining physical activity and obesity relationships,
(2) studies to improve methodology of assessment of physical activity
and energy balance, and (3) studies to test intervention approaches
that incorporate physical activity for obesity prevention or treatment
related to chronic diseases.
HEALTHY PEOPLE 2010
The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2010," a
PHS led national activity for setting priority areas. This PA,
Physical Activity And Obesity Across Chronic Diseases, is related to
one or more of the priority areas. Potential applicants may obtain a
copy of "Healthy People 2010" at http://www.health.gov/healthypeople
ELIGIBILITY REQUIREMENTS
Applications may be submitted by domestic and foreign for-profit and
nonprofit organizations, public and private, such as universities,
colleges, hospitals, laboratories, units of State and local
governments, and eligible agencies of the Federal Government.
Racial/ethnic minority individuals, women, and persons with
disabilities are encouraged to apply as principal investigators.
MECHANISM OF SUPPORT
The primary mechanism of support will be the National Institutes of
Health (NIH) research project grant (R01). Additional mechanisms of
support are available through individual Institutes and Centers (ICs).
Potential applicants are encouraged to contact Program Staff in the
appropriate ICs (see INQUIRIES, section) for further information about
the mechanisms available. Planning, direction, and execution of the
program will be the responsibility of the applicant. Any applicant
planning to submit a new investigator-initiated grant application
requesting $500,000 or more in direct costs in any one year must
contact Institute Program Staff before submitting the application.
Furthermore, the applicant must obtain agreement from Institute staff
that the Institute will accept the application for consideration for
award. Additional information about this policy can be found in the
NIH Guide Volume 25, Number 14, May 3, 1996. Responses to Program
Announcements are subject to this policy.
Applications requesting less than $250,000 in direct costs per year
must be in modular grant format. Specific application instructions
have been modified to reflect "MODULAR GRANT" and "JUST-IN-TIME"
streamlining efforts being examined by the NIH. Complete and detailed
instructions and information on Modular Grant applications can be found
at http://grants.nih.gov/grants/funding/modular/modular.htm
RESEARCH OBJECTIVES
Background
An estimated 97 million adults in the U.S. are overweight or obese
(Body Mass Index {BMI, kg/(MxM} greater than or equal to 25.0). The
Dietary Guidelines for Americans, (published by the World Health
Organization) and the 1998 NIH Clinical Guidelines on the
Identification, Evaluation, and Treatment of Overweight and Obesity in
Adults (See http://www.nhlbi.nih.gov/guidelines/obesity/ob_home.htm)
all use a body mass index (BMI) of less than 25.0 to define the upper
limit of the healthy weight range, greater than 50 percent of the adult
population is above this range. According to numerous recent reports,
the prevalence of overweight and obesity in the U.S. is increasing
dramatically. Based on the BMI cut-point of 30.0, which defines
obesity, 20 percent of men and 25 percent of women were obese in 1988-
1994 (NHANES III) compared with 12 percent of men and 16 percent of
women in 1971-74 (NHANES I).
Overweight is especially prevalent among certain racial and ethnic
groups. For example, 66 percent of African-American and Mexican-
American women are estimated to be overweight (NHANES III).
Furthermore, the increasing prevalence of overweight is not limited to
adults, but is observed in children, in both genders and in all
subpopulations.
Morbidity associated with overweight and obesity is considerable.
Obesity is a risk factor for Type II diabetes mellitus and for
cardiovascular disease as well as several other medical conditions.
The risk of diabetes increases as BMI increases, with the relative risk
of diabetes increasing by about 25 percent for each unit of BMI over
22. Overweight and obesity are also associated with increased
morbidity and mortality from coronary heart disease (CHD), studies have
found a three-fold increase in rate of coronary heart disease in women
with BMIs of 29 or greater compared with women with BMIs less than 21,
and a 10 percent increase in coronary events in men with each BMI unit
above 22. Hypertension prevalence increases from 16-18 percent to 32-
38 percent as BMI goes from less than 25 to greater than 30, and a
similar relationship, although not as dramatic, is seen between BMI and
high blood cholesterol. These problems can be ameliorated, or
sometimes reversed, through weight loss.
The relationship between physical activity and obesity appears to be
complex, and requires further study. The 1996 Surgeon General’s Report
on Physical Activity and Health concluded that physical activity is
important for weight control, primarily because of the positive
findings from studies testing the effects of physical activity on
weight loss. However, the report also stated: It is commonly believed
that physically active people are less likely to gain weight over the
course of their lives and are thus more likely to have a lower
prevalence of obesity than inactive people: accordingly, it is also
commonly believed that low levels of physical activity are a cause of
obesity. Few data, however, exist to evaluate the truth of these
suppositions. The report called for research to determine the most
important features of physical activity that confer specific health
benefits. For example, what specific combination(s) of type,
frequency, duration, intensity, and pattern of physical activity best
contributes to weight control or weight loss.
The 1998 NIH Clinical Guidelines on the Identification, Evaluation, and
Treatment of Overweight and Obesity in Adults Report indicates that
more research is needed on effects on body weight/obesity of different
lengths of physical activity interventions, different formats and
intensities of physical activity, and different forms of physical
activity in combination with diet, as well as effects of physical
activity on body fat distribution, e.g., abdominal fat. The
recommendations of this report for future research includes the need to
determine the optimal amount of physical activity to promote weight
loss, maintenance of weight loss, and prevention of obesity, as well as
strategies to preserve muscle and bone in the face of weight loss.
Research is needed on the effects of pharmacologic intervention for
weight loss on cardiorespiratory fitness. Research is also needed on
environmental and population-based intervention methods for weight
control that incorporate physical activity. These studies should
address high-risk populations for obesity and low levels of physical
activity including underserved population segments, e.g., minorities
and low socioeconomic (SES) groups.
Education about the long-term health consequences and risks associated
with overweight and how to achieve and maintain a preferred weight is
necessary. While many individuals attempt to lose weight, studies show
that within five years a majority of them regain the weight. In order
to maintain weight loss, good dietary habits must be coupled with
increased physical activity, and these must become permanent lifestyle
changes. It is still not clear, however, which behavioral approaches
are best for achieving these changes, particularly long-term. A 1998
NHLBI workshop on Maintenance of Behavior Change in Cardiorespiratory
Risk Reduction concluded that additional research is needed to examine
factors associated with long-term maintenance of weight loss, long-term
maintenance of increased physical activity levels, and the relationship
between the two. In addition, the question of whether physical
activity enhances long-term maintenance of weight loss has not been
formally examined in randomized trials.
NIDDK, in cooperation with NCI, NHLBI, NIA, NIAMS, and the President’s
Council on Physical Fitness and Sports, held a conference on the topic
of Physical Activity and Obesity in 1992. This conference assessed
research activities in this area and posed several research questions
that have yet to be adequately addressed and that are included in this
PA.
Research Scope
A broad range of specific research questions and study approaches are
relevant to this Program Announcement. The following are examples of
research topics and study approaches that are relevant. Applicants are
encouraged to consider these questions, when relevant, in relation to
persons with and without morbid conditions (such as hypertension,
diabetes, arthritis). Likewise, applicants are encouraged to provide a
rationale for the type of physical activity (e.g., aerobic, anaerobic,
resistance) that they propose in their applications.
1. Physical Activity and Obesity Relationships
o Studies to examine the relationships between type and amount of
physical activity and dietary intake, including caloric expenditure,
caloric intake and dietary macronutrient composition.
o Studies to examine the relationships between patterns of aerobic,
anaerobic, and resistance exercise with body weight, body composition,
and body fat distribution.
o Studies to examine interactions between the genetics of obesity and
physical activity levels on obesity phenotypes.
o Studies to examine the psychological and quality of life benefits of
physical activity.
o Studies to examine the determinants (personal, familial, cultural,
environmental and policy) for engaging in and maintaining physical
activity and good nutrition practices, particular attention can be paid
to various subpopulations, defined by gender, age, ethnicity, and/or
socioeconomic status who may be at risk for developing obesity.
o Prospective studies to examine tracking of dietary intake and eating
behavior and physical activity patterns, and the relationships between
the two, from childhood to adulthood.
o Prospective studies to examine the relationship between physical
activity and obesity or weight gain, particularly focusing on life
stages where the risk of obesity development is highest (e.g.,
adolescence, menopause, older age).
2. Assessment Methodology Studies
o Validation of improved methods for assessment of energy intake and
expenditure and levels of physical activity, as well as, improvement of
measures in special population segments based on race/ethnicity and
socioeconomic status.
o Improved methods for measuring skeletal muscle and adipose tissue
metabolic processes in response to exercise.
o Improved methods for measuring the type (resistance vs. aerobic) and
amount of physical activity behavior (frequency, intensity, duration),
the energy cost associated with physical activity, energy intake, and
energy balance.
o Improved methods for measuring the impact--both positive and
negative--of physical activity in subpopulations (defined by gender,
age, ethnicity, socioeconomic status) on various outcomes such as
quality of life.
o Improved methods for assessment of energy metabolism, body fat, and
body fat distribution, including visceral fat.
3. Intervention Studies
o Test the effects on body weight/obesity of different lengths of
physical activity interventions, different formats and intensities of
physical activity, and different forms of physical activity in
combination with diets, as well as, effects of physical activity on
body fat distribution e.g. abdominal fat
o Examine the effects of physical activity patterns on changes in
eating practices.
o Determine the long-term effects of various approaches to physical
activity interventions (including different behavioral approaches as
well as different type and amount of physical activity) on weight loss
and maintenance.
o Develop, implement, and evaluate psychobiobehavioral programs for
parents and their children utilizing nutritional counseling, dietary
changes, and exercise (preferably games and sports) to prevent or
attenuate problems of overweight and obesity.
o Evaluate the psychological effects of being overweight or obese at
different developmental stages of childhood and/ or the psychological
effects of participating in successful or unsuccessful weight loss
programs.
o Compare peer-oriented weight loss programs for overweight and obese
children and adolescents with parent-child oriented programs.
o Examine the optimal mixture of physical activity and dietary intake
for promoting weight loss and long-term maintenance of weight loss,
examine whether increased physical activity alone or in combination
with diet can prevent obesity or weight gain.
o Develop/test interventions to increase physical activity and examine
their effects on weight, on the changes in risk factors for obesity-
related diseases, and on the use of health care services. These
interventions can take place in a variety of settings, for example,
health maintenance organizations, primary care practices, work sites,
armed services, community groups, schools, etc.
o Test the effects the environmental and population-based intervention
methods for weight control, including those that incorporate physical
activity.
INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS
It is the policy of the NIH that women and members of minority groups
and their sub-populations must be included in all NIH-supported
biomedical and behavioral research projects involving human subjects,
unless a clear and compelling rationale and justification are provided
indicating that inclusion is inappropriate with respect to the health
of the subjects or the purpose of the research. This policy results
from the NIH Revitalization Act of 1993 (Section 492B of Public Law
103-43).
All investigators proposing research involving human subjects should
read the UPDATED "NIH Guidelines for Inclusion of Women and Minorities
as Subjects in Clinical Research," published in the NIH Guide for
Grants and Contracts on August 2, 2000
(http://grants.nih.gov/grants/guide/notice-files/NOT-OD-00-048.html), a
complete copy of the updated Guidelines are available at
http://grants.nih.gov/grants/funding/women_min/guidelines_update.htm:
The revisions relate to NIH defined Phase III clinical trials and
require: a) all applications or proposals and/or protocols to provide a
description of plans to conduct analyses, as appropriate, to address
differences by sex/gender and/or racial/ethnic groups, including
subgroups if applicable, and b) all investigators to report accrual,
and to conduct and report analyses, as appropriate, by sex/gender
and/or racial/ethnic group differences.
INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN
SUBJECTS
It is the policy of NIH that children (i.e., individuals under the age
of 21) must be included in all human subjects research, conducted or
supported by the NIH, unless there are scientific and ethical reasons
not to include them. This policy applies to all initial (Type 1)
applications submitted for receipt dates after October 1, 1998.
All investigators proposing research involving human subjects should
read the "NIH Policy and Guidelines on the Inclusion of Children as
Participants in Research Involving Human Subjects" that was published
in the NIH Guide for Grants and Contracts, March 6, 1998, and is
available at the following URL address:
http://grants.nih.gov/grants/guide/notice-files/not98-024.html
Investigators also may obtain copies of these policies from the program
staff listed under INQUIRIES. Program staff may also provide additional
relevant information concerning the policy.
URLS IN NIH GRANT APPLICATIONS OR APPENDICES
All applications and proposals for NIH funding must be self-contained
within specified page limitations. Unless otherwise specified in an NIH
solicitation, internet addresses (URLs) should not be used to provide
information necessary to the review because reviewers are under no
obligation to view the Internet sites. Reviewers are cautioned that
their anonymity may be compromised when they directly access an
Internet site.
APPLICATION PROCEDURES
Applications are to be submitted on the grant application form PHS 398
(rev. 4/98) and will be accepted at the standard application deadlines
as indicated in the application kit. Application kits are available at
most institutional offices of sponsored research and may be obtained
from the Division of Extramural Outreach and Information Resources,
National Institutes of Health, 6701 Rockledge Drive, MSC 7910,
Bethesda, MD 20892-7910, telephone 301/710-0267, email:
[email protected].
Applicants planning to submit an investigator-initiated new (type 1),
competing continuation (type 2), competing supplement, or any
amended/revised version of the preceding grant application types
requesting $500,000 or more in direct costs for any year are advised
that he or she must contact the Institute or Center (IC) program staff
before submitting the application, i.e, as plans for the study are
being developed. Furthermore, the application must obtain agreement
from the IC staff that the IC will accept the application for
consideration for award. Finally, the applicant must identify, in a
cover letter sent with the application, the staff member and Institute
or Center who agreed to accept assignment of the application. This
policy requires an applicant to obtain agreement for acceptance of both
any such application and any such subsequent amendment. Refer to the
NIH Guide for Grants and Contracts, March 20, 1998 at
http://grants.nih.gov/grants/guide/notice-files/not98-030.html
Applications requesting less than $250,000 in direct costs per year
must be submitted in modular grant format. The modular grant concept
establishes specific modules in which direct costs may be requested as
well as a maximum level for requested budgets. Only limited budgetary
information is required under this approach. The just-in-time concept
allows applicants to submit certain information only when there is a
possibility for an award. It is anticipated that these changes will
reduce the administrative burden for the applicants, reviewers and
Institute staff. The research grant application form PHS 398 (rev.
4/98) is to be used in applying for these grants, with the
modifications noted below.
SPECIFIC INSTRUCTIONS FOR MODULAR GRANT APPLICATIONS
BUDGET INSTRUCTIONS
Modular Grant applications will request direct costs in $25,000
modules, up to a total direct cost request of $250,000 per year.
(Applications that request more than $250,000 direct costs in any year
must follow the traditional PHS 398 application instructions.) The
total direct costs must be requested in accordance with the program
guidelines and the modifications made to the standard PHS 398
application instructions described below:
PHS 398
o FACE PAGE: Items 7a and 7b should be completed, indicating Direct
Costs (in $25,000 increments up to a maximum of $250,000) and Total
Costs [Modular Total Direct plus Facilities and Administrative (F&A)
costs] for the initial budget period Items 8a and 8b should be
completed indicating the Direct and Total Costs for the entire proposed
period of support.
o DETAILED BUDGET FOR THE INITIAL BUDGET PERIOD - Do not complete Form
Page 4 of the PHS 398. It is not required and will not be accepted with
the application.
o BUDGET FOR THE ENTIRE PROPOSED PERIOD OF SUPPORT - Do not complete
the categorical budget table on Form Page 5 of the PHS 398. It is not
required and will not be accepted with the application.
o NARRATIVE BUDGET JUSTIFICATION - Prepare a Modular Grant Budget
Narrative page. (See
http://grants.nih.gov/grants/funding/modular/modular.htm for sample
pages.) At the top of the page, enter the total direct costs requested
for each year. This is not a Form page.
o Under Personnel, list all project personnel, including their names,
percent of effort, and roles on the project. No individual salary
information should be provided. However, the applicant should use the
NIH appropriation language salary cap and the NIH policy for graduate
student compensation in developing the budget request.
For Consortium/Contractual costs, provide an estimate of total costs
(direct plus facilities and administrative) for each year, each rounded
to the nearest $1,000. List the individuals/organizations with whom
consortium or contractual arrangements have been made, the percent
effort of all personnel, and the role on the project. Indicate whether
the collaborating institution is foreign or domestic. The total cost
for a consortium/contractual arrangement is included in the overall
requested modular direct cost amount. Include the Letter of Intent to
establish a consortium.
Provide an additional narrative budget justification for any variation
in the number of modules requested.
o BIOGRAPHICAL SKETCH - The Biographical Sketch provides information
used by reviewers in the assessment of each individual"s
qualifications for a specific role in the proposed project, as well as
to evaluate the overall qualifications of the research team. A
biographical sketch is required for all key personnel, following the
instructions below. No more than three pages may be used for each
person. A sample biographical sketch may be viewed at:
http://grants.nih.gov/grants/funding/modular/modular.htm
- Complete the educational block at the top of the form page,
- List position(s) and any honors,
- Provide information, including overall goals and responsibilities, on
research projects ongoing or completed during the last three years.
- List selected peer-reviewed publications, with full citations,
o CHECKLIST - This page should be completed and submitted with the
application. If the F&A rate agreement has been established, indicate
the type of agreement and the date. All appropriate exclusions must be
applied in the calculation of the F&A costs for the initial budget
period and all future budget years.
o The applicant should provide the name and phone number of the
individual to contact concerning fiscal and administrative issues if
additional information is necessary following the initial review.
The title and number of the program announcement must be typed on line
2 of the face page of the application form and the YES box must be
marked.
Submit a signed, typewritten original of the application, including the
Checklist, and five signed photocopies in one package to:
CENTER FOR SCIENTIFIC REVIEW
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040, MSC 7710
BETHESDA, MD 20892-7710
BETHESDA, MD 20817 (for express/courier service)
REVIEW CONSIDERATIONS
Applications will be reviewed for completeness by the Center for
Scientific Review. Applications that are complete will be evaluated
for scientific and technical merit by an appropriate peer review group
convened in accordance with NIH peer review procedures. As part of the
initial merit review, all applications will receive a written critique
and undergo a process in which only those applications deemed to have
the highest scientific merit, generally the top half of applications
under review, will be discussed, assigned a priority score, and receive
a second-level review by the appropriate National Advisory Council or
Board.
The goals of NIH-supported research are to advance our understanding of
biological systems, improve the control of disease, and enhance health.
In the written review, comments on the following aspects of the
application will be made in order to judge the likelihood that the
proposed research will have a substantial impact on the pursuit of
these goals. Each of these criteria will be addressed and considered
in the assignment of the overall score:
1. Significance: Does this study address an important problem? If the
aims of the application are achieved, how will scientific knowledge be
advanced? What will be the effect of these studies on the concepts or
methods that drive this field?
2. Approach: Is the conceptual framework, design, methods, and analyses
adequately developed, well integrated, and appropriate to the aims of
the project? Does the applicant acknowledge potential problem areas
and consider alternative tactics?
3. Innovation: Does the project employ novel concepts, approaches or
methods? Are the aims original and innovative? Does the project
challenge existing paradigms or develop new methodologies or
technologies?
4. Investigator: Is the investigator appropriately trained and well
suited to carry out this work? Is the work proposed appropriate to the
experience level of the principal investigator and other researchers
(if any)?
5. Environment: Does the scientific environment in which the work will
be done contribute to the probability of success? Do the proposed
experiments take advantage of unique features of the scientific
environment or employ useful collaborative arrangements? Is there
evidence of institutional support?
In addition, the adequacy of plans to include both genders and
minorities and their subgroups as appropriate for the scientific goals
of the research will be reviewed. Plans for the recruitment and
retention of subjects will also be evaluated.
The Scientific Review Group will also examine the provisions for the
protection of human and animal subjects, the safety of the research
environment, and conformance with the NIH Guidelines for the Inclusion
of Women, Minorities, and Children as Subjects in Clinical Research.
AWARD CRITERIA
Applications will compete for available funds with all other
recommended applications assigned to that Institute. The following
will be considered in making funding decisions: quality of the proposed
project as determined by peer review, availability of funds, and
program priority.
INQUIRIES
Inquiries are encouraged. We welcome the opportunity to clarify any
issues or questions from potential applicants.
Direct inquiries regarding programmatic issues to:
Richard P. Troiano, Ph.D., R.D.
CDR, USPHS
National Cancer Institute, DCCPS, ARP
EPN 4005
6130 Executive Blvd, MSC 7344
Bethesda, MD 20892-7344
Telephone: 301/496-8500, direct 301/435-6822
FAX: 301/435-3710
E-mail: [email protected] or [email protected]
Denise G. Simons-Morton, M.D., Ph.D.
Leader, Prevention Scientific Research Group
Clinical Applications and Prevention Program
Division of Epidemiology and Clinical Applications
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Room 8138, MSC 7936
Telephone: (301) 435-0384
FAX: (301) 480-1669
Email: [email protected]
Chhanda Dutta, Ph.D.
Geriatrics Program
National Institute on Aging
7201 Wisconsin Avenue, Suite 3E-327
Bethesda, MD 20892-9205
Telephone: (301) 435-3048
FAX: (301) 402-1784
Email: [email protected]
James S. Panagis, M.D., M.P.H.
Orthopaedics Program
NIAMS
6500 Center Drive - Room 5AS-37K
Bethesda, MD 20892-6500
TEL: 301-594-5055
FAX: 301-480-4543
Email: [email protected]
Susan Yanovski, M.D.
Division of Digestive Diseases and Nutrition
National Institute of Diabetes and Digestive Kidney Diseases
6707 Democracy Blvd, Room 612
Bethesda, MD 20892
Telephone: (301) 594-8882
FAX: (301) 480-3504
Email: [email protected]
Pamela E Starke-Reed, Ph.D.
NIH, Division of Nutrition Research Coordination
Rockledge 1, Suite 8048, MSC 7973
Bethesda, MD 20892-7973
Telephone: (301) 594-8805
FAX: (301) 480-3768
Email: [email protected]
Lynne M. Haverkos, M.D., MPH
Child Development and Behavior Branch
National Institute of Child Health and Human Development
6100 Executive Boulevard, Room 4B05B, MSC 7510
Bethesda, MD 20892-7510
Telephone: (301) 435-6881
FAX: (301) 480-7773
E-mail: [email protected]
Hilary Sigmon, Ph.D. R.N.
Division of Intramural Programs
National Institute of Nursing Research
45 Center Drive, Room 3AN18 MSC 6300
Bethesda, MD 20892-6300
Telephone: (301) 594-5970
FAX: (301) 480-8260
Email: [email protected]
Direct inquiries regarding fiscal and administrative matters to:
Ms. Linda Whipp
Grants and Contracts Management Office
National Institute on Aging
7201 Wisconsin Avenue, Suite 2N212
Bethesda, MD 20892-9205
Telephone: (301) 496-1472
FAX: (301) 402-3672
Email: [email protected]
Melinda B. Nelson
Grants Management Branch
NIAMS
6500 Center Drive - Room 5AS-49F
Bethesda, MD 20892-6500
TEL: 301-594-3535
FAX: 301-480-5450
Email: [email protected]
Douglas Shawver
Office of Administrative Management
National Institute of Child Health and Human Development
6100 Executive Boulevard, Room 8A07, MSC 7510
Bethesda, MD 20892-7510
Telephone: (301) 435-6999
FAX: (301) 402-0915
Email: [email protected]
Sharon Bourque
Division of Extramural Activities
National Institute of Diabetes and Digestive Kidney Diseases
6707 Democracy Blvd, Room 612
Bethesda, MD 20892
Telephone: (301) 594-8846
FAX: (301) 480-3504
Email: [email protected]
Ms. Sally York
Grants Management Specialist
National Institute of Nursing Research
45 Center Drive MSC 6300
Bethesda, Maryland 20892-6300
Tel: 301-594-2154
FAX: 301-480-8260
Email [email protected]
AUTHORITY AND REGULATIONS
This program is described in the Catalog of Federal Domestic Assistance
No. 93.393, 93.399, 93.846, 93.865, 93.866, 93.837, 93.847, 93.848,
93.361, and 93.849. Awards are under authorization of the Public
Health Service Act, Title IV, Part A (Public Law 78-410, as amended by
Public Law 99-158, 42 USC 241 and 285) and administered under PHS
grants policies and Federal Regulations 42 CFR 52 and 45 CFR Part 74.
This program is not subject to the intergovernmental review
requirements of Executive Order 12372 or Health Systems Agency review.
The PHS strongly encourages all grant and contract recipients to
provide a smoke-free workplace and promote the non-use of all tobacco
products. In addition, Public Law 103-227, the Pro-Children Act of
1994, prohibits smoking in certain facilities (or in some cases, any
portion of a facility) in which regular or routine education, library,
day care, health care, or early childhood development services are
provided to children. This is consistent with the PHS mission to
protect and advance the physical and mental health of the American
people.
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
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