Release Date:  April 20, 1999  


National Cancer Institute

A pre-application informational meeting for those investigators considering
submitting applications in response to three RFAs related to the Early Detection
Research Network (EDRN) will be held on Monday, May 17, 1999 from 1:00 P.M. to
5:00 P.M. at the Natcher Conference Center, Room E1 and E2.  Representatives from
the NCI's Cancer Biomarkers Research Group, Grants Administration Branch and
Special Review, Referral and Resources Branch will be available to provide
information and to answer questions  relevant to applications responding to this
RFA.  Transcripts will be available upon request for investigators who are unable
to attend.

The meeting will focus on three components of the EDRN:

(1) Clinical and Epidemiologic Centers (RFA CA 99-007)
(2) Biomarkers Validation Laboratories (RFA CA-99-008)
(3) Data Management and Coordinating Center (RFA CA-99-011)

The complete text of each RFA is available in the NIH Guide for Grants and
Contracts at the following URL:

The purpose of the EDRN is to establish a scientific consortium of investigators,
academic as well as industrial, with resources for basic, translational, and
clinical research.  The EDRN will have four components -- Biomarkers
Developmental Laboratories (for which an informational meeting already has been
held), Biomarkers Validation Laboratories, Clinical/Epidemiologic Centers and the
Data Management and Coordinating Center.  The Biomarkers Developmental
Laboratories will have responsibility for the development and characterization
of new or refinement of existing biomarkers; the Biomarkers Validation
Laboratories will serve as a Network resource for clinical and laboratory
validation of biomarkers, which include technological development and refinement;
and the Clinical/Epidemiology Centers will conduct clinical and epidemiological
research regarding the clinical application of biomarkers.  The Data Management
and Coordinating Center will be responsible for coordinating the EDRN research
activities, providing logistic supports for the meetings, and conducting
statistical and computational research.


Investigators who plan to attend should contact the NCI staff member listed below
by May 10, 1999 to confirm their attendance and to obtain further information. 

Ms. Ava Bradshaw
Cancer Biomarkers Research Group
Division of Cancer Prevention
National Cancer Institute
6130 Executive Boulevard, Room 330, MSC 7346
Bethesda, MD  20892-7388
Telephone:  (301) 435-8397
Fax: (301) 402-0816

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