Release Date:  September 4, 1998

RFA:  HL-98-007


National Heart, Lung, and Blood Institute

This is an amendment to RFA HL-98-007, "Specialized Centers of Research in
Ischemic Heart Disease," which appeared in the NIH Guide February 20, 1998.

Under the section heading - FUNDS AVAILABLE - substitute the following paragraph:

Applicants may request up to $1,220,000 direct costs, not including indirect
costs for collaborating institutions, in the first year.  Projects within a
center that focus on complementary or alternative medicine research, in the areas
defined under the RESEARCH OBJECTIVES, are not included in determining this limit
of $1,220,000 direct costs.  Competing renewal applicants may request an
increase, in their budget in the first competing year (Year 06), not to exceed
10 percent of the costs awarded in the last noncompeting award year (Year 05) or
$1,220,000, whichever is greater.  Applicants may request up to a two percent
increase for subsequent noncompeting years.  It is anticipated that ten SCOR
grants, for a five year project period, at an estimated first year total cost of
$15.886 million, will be supported.  In addition, it is anticipated that $1.6
million will be  available to support projects focussing on complementary or
alternative medicine, as defined below.  Requests to support complementary or
alternative medicine projects cannot exceed $400,000 in total costs (including
direct and indirect costs and project costs associated with core components) per


Written and telephone inquiries concerning the RFA are encouraged.  The
opportunity to clarify any issues or questions from potential applicants is

Direct inquiries regarding programmatic issues and requests for supplemental
instructions to:

John Fakunding, Ph.D.
Division of Heart and Vascular Diseases
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Suite 9200, MSC 7940
Bethesda, MD  20892-7940
Telephone:  (301) 435-0505
FAX:  (301) 480-1454

Direct inquiries regarding fiscal matters to:

Marie Willett
Division of Extramural Affairs
National Heart, Lung, and Blood Institute
6701 Rockledge Drive, Room 7156, MSC 7926
Bethesda, MD  20892-7926
Telephone:  (301) 435-0144
FAX:  (301) 480-3310

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