Release Date:  February 13, 1998


National Heart, Lung, and Blood Institute


The purpose of this notice is to inform the scientific community that a
limited competition RFA is being issued.  A limited number of Institutions
have been asked to submit applications to provide a centralized rat database. 
This centralized database will enable investigators from a large number of
research areas and interests with a range of computer expertise to have full
access to rat genetic and genomic information by using only one simple user
interface.  A centralized database will prevent the problems of diffuse,
multi-institutional database efforts and the perpetuation of these databases
on the World Wide Web which can result in loss of available data due to an
investigator's inability to locate and access the data.  A centralized
database will also minimize the difficultly in integrating data from multiple
sources.  In addition to genomic and genetic data, a centralized database will
also include other information, such as phenotype data, strain
characteristics, and physiological data.  This centralized database will build
upon the existing grants funded as part of the NIH Rat Genome Project and the
NIH Rat EST Project to ensure that the products of this broad NIH supported
multi-institutional investment are used to the maximal extent and benefit. 
Thus a limited competition for the further development of the centralized, Rat
Genome Database will be conducted.


Inquiries regarding the implementation of this effort may be directed to:

Ronald G. Geller, Ph.D.
Director, Division of Extramural Affairs
National Heart, Lung, and Blood Institute
6701 Rockledge Drive
Bethesda, MD 20892-7922
Telephone:  (301) 435-0260
Email:  GellerR@gwgate.nhlbi.nih.gov

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