NIH GUIDE, Volume 26, Number 9, March 21, 1997


P.T. 34


  Immune System Disorders 





National Institute of Allergy and Infectious Diseases


The Clinical Immunology Branch, Division of Allergy, Immunology, and

Transplantation (DAIT), National Institute of Allergy and Infectious

Diseases (NIAID) has a requirement for the acquisition of a registry

for U.S. residents affected by several primary immunodeficiency

diseases.  The work will require expertise and knowledge of these

diseases (including the complex clinical manifestations and the

socioeconomic impact on affected families); interactions with

individuals affected by these diseases, their physicians, and

researchers in primary immunodeficiency diseases; and expertise and

knowledge of all aspects of the operation of a registry.  The

diseases are: Severe Combined Immunodeficiency Disease (SCID), X-

linked Agammaglobulinemia (XLA), Wiskott-Aldrich Syndrome (WAS),

Common Variable Immunodeficiency (CVID), Chronic Granulomatous

Disease (CGD), DiGeorge Anomaly, Leukocyte Adhesion Deficiency (LAD),

and Hyper IgM Syndrome.  The contract will have two components, A and

B.  The registry for SCID, XLA, WAS, CVID and CGD will comprise Part

A, for which a single, completion type contract will be awarded.

Part B describes activities for the Government to support at its

option, which may include expansion of the registry to include any

one, two, or all three of the diseases DiGeorge Anomaly, LAD, and

Hyper IgM syndrome.  It is anticipated that one cost-reimbursement,

completion contract will be awarded for a period of five years.


Request for Proposals (RFP) NIAID-DAIT-97-11 is available

electronically and may be accessed through the NIH Home Page or the

NIH Gopher by using the following electronic mail addresses and

instructions:  NIH Home Page (via the World Wide Web): Access the NIH

Home Page by using .  Once you are at the NIH Home

Page, select "Grants & Contracts", then under the "Contracts" page

heading, select "Funding Opportunities" to access the "R&D Requests

for Proposals (RFP)" in the gopher directory.  Once in the gopher

directory, select "RFPs Available:; "NIAID"; and finally, "RFP NIH-

NIAID-DAIT-97-11."  This RFP is only available via the NIH Home Page.

Instructions for this acquisition and for proper submission are set

forth at the Web Site mentioned above.  Following proposal submission

and the initial review process, offerors comprising the competitive

range will be requested to provide additional documentation to the

Contracting Officer.  Responses to this RFP will be due on or about

May 20, 1997.  Any responsible offeror may submit a proposal which

will be considered by the Government.  This advertisement does not

commit the Government to award a contract.




Questions regarding this RFP may be directed to:


Rosemary Hamill

Division of Allergy, Immunology, and Transplantation

National Institute of Allergy and Infectious Diseases

Federal Building, Room 3C07

Bethesda, MD  20892

Telephone:  (301) 496-0384




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