NIH GUIDE, Volume 25, Number 29, August 30, 1996


RFP AVAILABLE:  N01-BC-71006-21


P.T. 34


  Cell Lines 

  Tissue Culture 



National Cancer Institute


The Laboratory of Human Carcinogenesis (LHC), Division of Basic

Sciences (DBS), National Cancer Institute (NCI), National Institutes

of Health (NIH), is recompeting a four-year tissue-collection

contract.  Proposals are now being solicited from qualified firms to

provide the necessary resources for the collection of viable

surgical, biopsy and autopsy specimens from a variety of human

tissues and cells (lung, bronchus, colon, liver, pancreas) and other

biological specimens (pleural effusions, blood and urine) from donors

with epidemiological profiles prepared in specifically designed

patient questionnaires which include the relevant medical records.

The incumbent contractor is The University of Maryland at Baltimore

(Contract N01-BC-33010), which is scheduled to expire March 30, 1997.

The LHC subjects the tissues and cells to in vitro adaptability and

carcinogenesis, biochemical characterizations and assays of chemical

and oncogene-induced alterations of macromolecules, innovative

methods for determining populations at risk for certain carcinogens

by biochemical epidemiology survey.  Relevant studies are extenuated

by the application of xenotransplantation techniques for definitive

assay of chemically stimulated tumorigenesis.  Offerors must

demonstrate, in their technical proposal, their ability to facilitate

delivery of the nonfrozen viable tissues to the NCI in Bethesda,

Maryland within two hours of collection as a mandatory qualification

criteria of this solicitation.  Failure to demonstrate this element

at the time of original submission will result in the offeror~s

elimination from further consideration.  This contract will be

awarded as a multiple-year, cost-reimbursement, level-of-effort

(term) type contract with a required level-of-effort for all four

years of 50,284 person hours (an estimated 12,571 hours per year) and

incremental funding will be used.  t is anticipated that the RFP NIH-

NCI-N01-BC-71006-21 will be available electronically on or about

September 9, 1996, and may be accessed through either the NIH Gopher

or the NIH Home Page by using the following electronic mail addresses

and instructions:


1) The NIH Gopher address is GOPHER.NIH.GOV PORT 70.  Select ~Grant &

Research Information~ then select "R&D Requests for Proposals (RFP)".


2) The NIH Home Page (via World Wide Web) address is  Select "Grants & Contracts".  Select "R&D

Requests for Proposals (RFP)".




Proposals will be due 45 days following the actual date of RFP

issuance.  The NCI will consider proposals from all responsible

sources.  The RFP for this acquisition has been revised to include

only the Work Statement, deliverables and reporting requirements,

special requirements and mandatory qualifications (if any), Technical

Evaluation Criteria and proposal preparation instructions.  All

information required for the submission of an offer will be contained

in the electronic RFP package.  Organizations unable to access this

RFP electronically may request a copy in writing from:


Barbara A. Shadrick

Research Contracts Branch

National Cancer Institute

6120 Executive Boulevard, Room 620 - MSC 7224

Bethesda, MD  20892-7224

Telephone:  (301) 496-8611




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