RESOURCE FOR COLLECTION AND EVALUATION OF HUMAN TISSUE AND CELLS FROMDONORS WITH EPIDEMIOLOGY PROFILES NIH GUIDE, Volume 25, Number 29, August 30, 1996 RFP AVAILABLE: N01-BC-71006-21 P.T. 34 Keywords: Cell Lines Tissue Culture Epidemiology National Cancer Institute The Laboratory of Human Carcinogenesis (LHC), Division of Basic Sciences (DBS), National Cancer Institute (NCI), National Institutes of Health (NIH), is recompeting a four-year tissue-collection contract. Proposals are now being solicited from qualified firms to provide the necessary resources for the collection of viable surgical, biopsy and autopsy specimens from a variety of human tissues and cells (lung, bronchus, colon, liver, pancreas) and other biological specimens (pleural effusions, blood and urine) from donors with epidemiological profiles prepared in specifically designed patient questionnaires which include the relevant medical records. The incumbent contractor is The University of Maryland at Baltimore (Contract N01-BC-33010), which is scheduled to expire March 30, 1997. The LHC subjects the tissues and cells to in vitro adaptability and carcinogenesis, biochemical characterizations and assays of chemical and oncogene-induced alterations of macromolecules, innovative methods for determining populations at risk for certain carcinogens by biochemical epidemiology survey. Relevant studies are extenuated by the application of xenotransplantation techniques for definitive assay of chemically stimulated tumorigenesis. Offerors must demonstrate, in their technical proposal, their ability to facilitate delivery of the nonfrozen viable tissues to the NCI in Bethesda, Maryland within two hours of collection as a mandatory qualification criteria of this solicitation. Failure to demonstrate this element at the time of original submission will result in the offeror~s elimination from further consideration. This contract will be awarded as a multiple-year, cost-reimbursement, level-of-effort (term) type contract with a required level-of-effort for all four years of 50,284 person hours (an estimated 12,571 hours per year) and incremental funding will be used. t is anticipated that the RFP NIH- NCI-N01-BC-71006-21 will be available electronically on or about September 9, 1996, and may be accessed through either the NIH Gopher or the NIH Home Page by using the following electronic mail addresses and instructions: 1) The NIH Gopher address is GOPHER.NIH.GOV PORT 70. Select ~Grant & Research Information~ then select "R&D Requests for Proposals (RFP)". 2) The NIH Home Page (via World Wide Web) address is http://www.nih.gov. Select "Grants & Contracts". Select "R&D Requests for Proposals (RFP)". INQUIRIES Proposals will be due 45 days following the actual date of RFP issuance. The NCI will consider proposals from all responsible sources. The RFP for this acquisition has been revised to include only the Work Statement, deliverables and reporting requirements, special requirements and mandatory qualifications (if any), Technical Evaluation Criteria and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Organizations unable to access this RFP electronically may request a copy in writing from: Barbara A. Shadrick Research Contracts Branch National Cancer Institute 6120 Executive Boulevard, Room 620 - MSC 7224 Bethesda, MD 20892-7224 Telephone: (301) 496-8611 Email: SHADRICB@RCB.NCI.NIH.GOV .
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