NIH GUIDE, Volume 25, Number 29, August 30, 1996


PA NUMBER:  PA-96-070


P.T. 34


  Chronic Fatigue 

  Biomedical Research, Multidiscipl 


National Institute of Allergy and Infectious Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Mental Health

National Heart, Lung, and Blood Institute

National Institute of Environmental Health Sciences

National Institute of Nursing Research

National Institute of Diabetes and Digestive and Kidney Diseases

Office of Research on Women's Health


This notice is an addendum to PA-96-070, which was published in the

NIH Guide, Vol. 25, No. 28, August 16, 1996.


Within "Research Objectives and Experimental Approaches" the

following two topics are added to factors that may explain or have an

impact on CFS pathogenesis and areas need additional research:


o  association of altered sleep/wake physiology and the frequency of

sleep disorders/disturbances in CFS, including sleep related periodic

limb movements and sleep apnea


o relationship between CFS and disordered circadian functions




Direct inquiries regarding this addendum to:


Paul Velletri, Ph.D.

Division of Heart and Vascular Diseases

National Heart, Lung and Blood Institute

6701 Rockledge Drive, Suite 10193 - MSC 7956

Bethesda, MD  20892-7956

Telephone:  (301) 435-0560

FAX:  (301) 480-2849




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