BEHAVIORAL THERAPIES DEVELOPMENT PROGRAM - ADDENDUM NIH GUIDE, Volume 25, Number 27, August 9, 1996 PA NUMBER: PA 94-078 P.T. 34 Keywords: Rehabilitation/Therapy, Emotional Drugs/Drug Abuse Behavioral/Social Studies/Service National Institute on Drug Abuse PURPOSE This notice is an addendum, Innovative Stage 1 Behavioral Therapy Development Research, to program announcement PA-94-078, published in the NIH Guide, Vol. 22, No. 26, July 15, 1994. The purpose of this addendum is to encourage Stage 1 research on the development of new and innovative behavioral interventions for the treatment of drug addiction and the prevention or reduction of HIV risk behaviors in drug abuse treatment populations. The translation of basic behavioral science research into creative new behavioral therapies for drug addicts is the ultimate goal of this program announcement. The National Institute on Drug Abuse (NIDA) is supporting the study of behavioral therapies (including, but not limited to, psychotherapy, behavior therapy, cognitive therapy, family therapy, skills training, and counseling approaches) that will potentially have a significant impact on reducing drug abuse and addiction and reducing HIV/AIDS risk behaviors. For those investigators applying for grants under the Behavioral Therapies Development Program, this notice is meant to supplement Program Announcement PA-94-078, which is still in effect and should be consulted in conjunction with this addendum. RESEARCH OBJECTIVES Behavioral interventions remain the most common, and sometimes the only, treatments administered to individuals with drug use disorders. Many of these interventions or therapies have been shown to have some efficacy in promoting initial abstinence from drugs, reducing relapse, decreasing total drug use, or decreasing HIV risk behaviors. Nonetheless, many questions remain about the best ways to intervene behaviorally in the treatment of addiction, and for some individuals, existing behavioral interventions may not be sufficient. Developments in basic behavioral science could have a positive impact upon the development of behavioral therapies. However, emerging scientific knowledge does not always get rapidly incorporated into the behavioral therapy development process. The objectives of this announcement are to encourage research, based upon emerging basic behavioral research findings, on the development of: (1) creative new therapies for drug use disorders and (2) innovative behavioral approaches to HIV risk reduction in drug abusing populations. This Stage 1 research ultimately involves the translation of ideas from basic behavioral science into clearly defined behavioral interventions/therapies for individuals with addictive disorders. Innovative research is needed that is not only based upon basic behavioral research, but also incorporates basic behavioral research into the Stage 1 effort. Such novel developmental therapy/intervention research may build upon research from the following (and other) areas of basic behavioral science: o Cognition and decision-making o Learning and motivation o Behavior analysis o Developmental psychology o Personality and individual differences o Social psychology Creative Stage 1 research that is theoretically-driven and solidly based in any area of basic behavioral science is sought. Applicants may propose behavioral therapy/intervention studies aimed at drug addiction treatment, HIV risk reduction in treatment populations, or both. All applications must be submitted on the grant application form PHS 398 (rev. 5/95) using the standard receipt dates described in the form. INQUIRIES Direct inquiries regarding this addendum and program announcement PA- 94-078 to: Lisa Onken, Ph.D. Division of Clinical and Services Research National Institute on Drug Abuse 5600 Fishers Lane, Room 10A-10 Rockville, MD 20857 Telephone: (301) 443-0107 Email: lo10n@nih.gov .
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