NIH GUIDE, Volume 25, Number 27, August 9, 1996


PA NUMBER: PA 94-078


P.T. 34


  Rehabilitation/Therapy, Emotional 

  Drugs/Drug Abuse 

  Behavioral/Social Studies/Service 


National Institute on Drug Abuse




This notice is an addendum, Innovative Stage 1 Behavioral Therapy

Development Research, to program announcement PA-94-078, published in

the NIH Guide, Vol. 22, No. 26, July 15, 1994.  The purpose of this

addendum is to encourage Stage 1 research on the development of new

and innovative behavioral interventions for the treatment of drug

addiction and the prevention or reduction of HIV risk behaviors in

drug abuse treatment populations.  The translation of basic

behavioral science research into creative new behavioral therapies

for drug addicts is the ultimate goal of this program announcement.

The National Institute on Drug Abuse (NIDA) is supporting the study

of behavioral therapies (including, but not limited to,

psychotherapy, behavior therapy, cognitive therapy, family therapy,

skills training, and counseling approaches) that will potentially

have a significant impact on reducing drug abuse and addiction and

reducing HIV/AIDS risk behaviors.  For those investigators applying

for grants under the Behavioral Therapies Development Program, this

notice is meant to supplement Program Announcement PA-94-078, which

is still in effect and should be consulted in conjunction with this





Behavioral interventions remain the most common, and sometimes the

only, treatments administered to individuals with drug use disorders.

Many of these interventions or therapies have been shown to have some

efficacy in promoting initial abstinence from drugs, reducing

relapse, decreasing total drug use, or decreasing HIV risk behaviors.

Nonetheless, many questions remain about the best ways to intervene

behaviorally in the treatment of addiction, and for some individuals,

existing behavioral interventions may not be sufficient.

Developments in basic behavioral science could have a positive impact

upon the development of behavioral therapies.  However, emerging

scientific knowledge does not always get rapidly incorporated into

the behavioral therapy development process.  The objectives of this

announcement are to encourage research, based upon emerging basic

behavioral research findings, on the development of:  (1) creative

new therapies for drug use disorders and (2) innovative behavioral

approaches to HIV risk reduction in drug abusing populations.  This

Stage 1 research ultimately involves the translation of ideas from

basic behavioral science into clearly defined behavioral

interventions/therapies for individuals with addictive disorders.


Innovative research is needed that is not only based upon basic

behavioral research, but also incorporates basic behavioral research

into the Stage 1 effort.  Such novel developmental

therapy/intervention research may build upon research from the

following (and other) areas of basic behavioral science:


o  Cognition and decision-making

o  Learning and motivation

o  Behavior analysis

o  Developmental psychology

o  Personality and individual differences

o  Social psychology


Creative Stage 1 research that is theoretically-driven and solidly

based in any area of basic behavioral science is sought.  Applicants

may propose behavioral therapy/intervention studies aimed at drug

addiction treatment, HIV risk reduction in treatment populations, or



All applications must be submitted on the grant application form PHS

398 (rev. 5/95) using the standard receipt dates described in the





Direct inquiries regarding this addendum and program announcement PA-

94-078 to:


Lisa Onken, Ph.D.

Division of Clinical and Services Research

National Institute on Drug Abuse

5600 Fishers Lane, Room 10A-10

Rockville, MD  20857

Telephone:  (301) 443-0107




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