NIH GUIDE, Volume 25, Number 15, May 10, 1996




P.T. 34



  Bioelectric Phenomena 


National Institute of Neurological Disorders and Stroke


The Neural Prosthesis Program (NPP) of the National Institute of

Neurological Disorders and Stroke (NINDS) is supporting the

development of a microelectrode array capable of recording from up to

64 sites located on a probe with multiple penetrating shanks.  The

broad objectives of the project are to develop multi-channel

penetrating electrode arrays for both central nervous system (CNS)

and peripheral nervous system (PNS) recording that will operate

reliably in the hostile ionic environment within the body over

decades of use in chronic implants.  This will require the

integration of micromachined electrode structures with active

electronics and with integral flexible ribbon cables or with integral

telemetry systems.  This project will support the development and

testing of the chronic recording electrode arrays.  Electrode systems

that include active electronics and ribbon cables will be tested

in-vitro and in chronic animals.  Probes will be furnished to the NPP

for testing by other investigators.  The goal is to design,

fabricate, and test multiple-site intracortical recording

microelectrode probes.  The contractor shall also acquire or develop

associated cables, connectors, and head mounts to produce a reliable

signal path between the recording sites on a microelectrode probe and

an extracoporal mating connector.  This project will require

established expertise in micormachining, bioengineering, integrated

circuit design, integrated circuit fabrication, and animal studies.

It is anticipated that one award, on a cost-reimbursement basis, will

be made for a period of three years.




This is not a Request for Proposals (RFP).  RFP NIH-NINDS-96-10 will

be issued on or about May 15, 1996 with responses due approximately

60 days thereafter.  Interested organizations should request either a

streamlined version or the entire RFP document.  If no selection is

made, a streamlined version of the RFP will be provided, which

includes only the Statement of Work, deliverable and reporting

requirements, special requirements, and technical evaluation

criteria.  After examination of these documents, organizations

interested in responding must request the entire RFP in writing or by

FAX.  Requests must cite the RFP number and supply this office with

two self-addressed mailing labels.  All responsible sources may

submit a proposal that will be considered by the Government.


Contracting Officer


Contracts Management Branch

National Institute of Neurological Disorders and Stroke

7550 Wisconsin Avenue, Room 901 - MSC-9190

Bethesda, MD  20892-9190

FAX:  (301) 402-4225



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