CONSTRUCTION AND APPLICATION OF A FLOWCELL FOR ATTENUATED TOTAL REFLECTANCE-FOURIER-TRANSFORM INFRARED (ATR-FTIR)SPECTROMETER/SCANNING CONFOCAL LASER MICROSCOPE (SCLM) STUDIES OF ORAL MICROBIAL COMMUNITIES NIH GUIDE, Volume 25, Number 6, March 1, 1996 RFP AVAILABLE: NLM-96-104/VMS P.T. 34 Keywords: Instrumentation, Biological National Library of Medicine The National Institute of Dental Research (NIDR) has a requirement to develop a Fourier-Transform-Infrared-Spectroscopy (FTIR) flowcell for establishment and characterization for various conditioning films on a substratum appropriate to the oral milieu (e.g., dental enamel), and to reversibly install this flowcell on a Scanning Confocal Laser Microscope (SCLM) located at the National Institute of Dental Research (NIDR), NIH, thereby creating an instrument for on-line four-dimensional study of microbial attachment to conditioning films. The successful contractor will be provided access to the Leica TCS-4D SCLM located at NIDR, to test the suitability of the flowcell for use on the microscope stage to conduct preliminary tests. Integration onto the SCLM, and support to set necessary baseline parameters for studying orally-relevant biofilms are required. It is anticipated that a two-year, cost reimbursement (level of effort) type contract will be awarded. The total project effort is estimated at 3,400 labor hours over the two year period of performance. The skills of trained and experienced analytical chemists, microbiologists, microbial ecologists, materials science engineers and access to laboratory-scale (developmental) and projection-scale prism-coating facilities as well as analytical facilities (XPS, SIMS, and Auger) will be essential for the successful completion of this project. INQUIRIES Request for Proposals (RFP) No. NLM 96-104/VMS will be available on or about March 11, 1996, with proposals due on or about April 26, 1996. All responsible sources may submit a proposal which will be considered by the NIDR. This acquisition is being managed for the National Institute of Dental Research by the Office of Acquisitions Management at the National Library of Medicine. Verbal and FAX requests for the RFP will not be accepted, requests must be submitted in writing, addressed to: Valerie M. Syed Office of Acquisitions Management National Library of Medicine 8600 Rockville Pike Building 38A, Room B1N17 Bethesda, MD 20894
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