NIDDK ADDITIONAL INFORMATION FOR CAREER DEVELOPMENT AWARDS NIH GUIDE, Volume 24, Number 38, October 27, 1995 P.T. 34 Keywords: Biomedical Research, Multidiscipl Diabetes Metabolic Diseases 0715133 National Institute of Diabetes and Digestive and Kidney Diseases This addition to the National Institutes of Health (NIH) career development program announcements provides further guidance for potential applicants on the Independent Scientists Awards (K02) and the Mentored Clinical Scientist Development Award (K08) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The following guidelines are intended to supplement, not supplant, the NIH Guide for Grants and Contracts announcement (PA-95-053, Vol. 24, No. 15, April 28, 1995). Consultation with program staff is strongly encouraged prior to submitting an application. INDEPENDENT SCIENTISTS AWARD (K02) The purpose of the K02 awards is to provide support for newly independent scientists who require a period of intensive research focus to enhance their research careers so that they may realize their potential to contribute to their scientific fields. To be considered eligible, a candidate must have at least three years of independent, peer-reviewed research support (preferably NIDDK-sponsored) remaining at the intended start date of the award. All other requirements and review considerations are found in the above-referenced Guide announcement. MENTORED CLINICAL SCIENTIST DEVELOPMENT AWARD (K08) The purpose of the K08 award is to provide a flexible approach to training for individuals committed to pursuing an independent research career. The award supports a three-, four-, or five-year period of supervised research experience which may integrate didactic studies with laboratory or clinically based research in areas related to research programs in diabetes, endocrinology, cystic fibrosis, metabolic diseases, digestive diseases, nutrition, obesity, nephrology, hematology, and urology. The NIDDK recognizes the need to provide flexible strategies for new investigators who wish to obtain research experiences that will enable them to pursue independent research careers. Suitable candidates should have completed their clinical training and should be board-eligible. During the award period, they may work concurrently on a master's or doctoral degree. Because candidates exhibit a broad range of previous research experience, the program design should be tailored to individual needs that will foster research independence. The following two examples are illustrative of the spectrum of research backgrounds seen in eligible candidates, but they are not all inclusive. Applicants with Little or No Prior Research Experience These individuals will require a more structured format that includes didactic training and close supervision by an appropriate mentor. Such a program may consist of two components. The first one (usually lasting two to three years) may include both didactic study and initial laboratory experience conducted under the close supervision of an individual with extensive research experience. The didactic plan must be clearly elucidated and tailored to the candidate's specific needs. The second component (up to three years) will be a more intensive laboratory-based research experience under the guidance of an appropriate scientific mentor and planned to foster increasing independence through time. Candidates with More Research Experience These candidates typically have had at least two years of supervised research experience, have clearly delineated an area of research inquiry, and have demonstrated potential to pursue an independent research career as evidenced by their publication record. Given their research experience, the candidates' program plan should be outlined in greater detail, and the role of the sponsor(s), while still important for advice and guidance, is less intense. The needs of the candidate and the program will define the type of mentorship required. For example, the first component might benefit from the experience of a mentor recognized in a basic science discipline and in training, whereas the second component might require an individual with research-based experience in another area. It also may be that more than one mentor is appropriate for either component. In that case, a primary sponsor must be identified, and training responsibilities must be delineated. Up to $20,000 per year over the candidate's salary may be requested for research support. (If funds for a technician are requested, both the salary and fringe benefits are included in this amount.) The K08 application will be evaluated on the merit of the program design to foster the candidate's emerging research independence. Also factored into this will be the candidate's credentials and potential for a research career and the qualifications of the sponsor(s) and plans to provide the necessary guidance. INQUIRIES Questions regarding the Program Announcement (PA-95-053) or this document, may be directed to: Dr. Ronald Margolis Division of Diabetes, Endocrinology and Metabolic Diseases National Institute of Diabetes and Digestive and Kidney Diseases Building 45, Room 5AN12 Bethesda, MD 20892 Telephone: (301) 594-8819 Email: rm76f@nih.gov Dr. Judith Podskalny Division of Digestive Diseases and Nutrition National Institute of Diabetes and Digestive and Kidney Diseases Telephone: (301) 594-8876 Email: podskalnyj@ep.niddk.nih.gov Dr. Charles Rodgers Division of Kidney, Urologic and Hematologic Diseases National Institute of Diabetes and Digestive and Kidney Diseases Building 45, Room 6A19J Bethesda, MD 20892 Telephone: (301) 594-7717 Email: rodgersc@ep.niddk.nih.gov .
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