MUCOSAL PATHOGENS RESEARCH UNITS NIH GUIDE, Volume 23, Number 40, November 18, 1994 RFP AVAILABLE: NIH-NIAID-DMID-96-07 P.T. 34 Keywords: Infectious Diseases/Agents 0760044 National Institute of Allergy and Infectious Diseases The Respiratory Diseases Branch and Enteric Diseases Branch, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID) have a requirement for two Mucosal Pathogens Research Units (MPRU). These MPRUs will conduct basic research on host-pathogen interactions at mucosal surfaces, methods to maximize a protective mucosal immunity through the design of attenuated vectors or delivery systems, as well as Phase I and Phase II clinical trials to evaluate candidate vaccines and vaccine strategies and other preventive measures for infectious diseases of the enteric or respiratory systems. An MPRU provides volunteer populations, staff, facilities, and expertise to carry out such work that includes follow-up and focused epidemiologic-based studies. A variety of vaccine types (live-attenuated, inactivated, genetic, subunit, conjugated) for prevention of viral and bacterial illnesses are expected, as are vaccine strategies (use of adjuvants or delivery vehicles) designed to induce protective mucosal immunity. It is anticipated that two cost-reimbursement, level-of-effort type contracts will be awarded for a period of seven years. Of these two anticipated awards, one award is anticipated for an MPRU that will focus on enteric pathogens, and one award is anticipated for an MPRU that will focus on respiratory pathogens. The streamlined version of RFP NIH-NIAID-DMID-96-07 will be available on or about December 22, 1994 electronically through the NIH Gopher and Internet using the following electronic mail addresses and instructions: 1. To access the NIH Gopher: Point your gopher client to GOPHER@NIH.GOV PORT 70. 2. To access the NIH Grant Line (Internet): Configure your terminal emulator as: 1200 or 2400 baud, even parity, 7 data bits, 1 stop bit, Half Duplex. Using the procedure specified in your communication software, dial 1-301-402-2221. When you get a response indicating that you have been connected, then type ,GEN1 (the comma is mandatory) and press ENTER; you will be prompted by the NIH system for "INITIALS?". Type BB5 and press ENTER. You will then be prompted for "Account?". Type CCS2 and press ENTER. Please note that the RFP for this procurement has been streamlined to include only the Work Statement, deliverable and reporting requirements, special requirements and mandatory qualification, if any, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the streamlined RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation (e.g., Representations and Certifications) to the Contracting Officer. PAPER COPIES OF THIS RFP WILL NOT BE DISTRIBUTED. INQUIRIES Any responsible offeror may submit a proposal that will be considered by the Government. Responses to this RFP will be due on April 14, 1995. This advertisement does not commit the Government to award a contract. Inquiries regarding this RFP may be directed to: Anthony Murray Contracts Management Branch National Institute of Allergy and Infectious Diseases Solar Building, Room 3C07 Bethesda, MD 20892 Telephone: (301) 496-6424 .
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