ENHANCING RECOVERY IN CORONARY HEART DISEASE (ENRICHD) PATIENTS -CLINICAL UNITS NIH GUIDE, Volume 23, Number 33, September 16, 1994 RFP AVAILABLE: NHLBI-HC-94-28 P.T. Keywords: National Heart, Lung, and Blood Institute The National Heart, Lung, and Blood Institute (NHLBI) is soliciting proposals from organizations/institutions to serve as clinic units in a multicenter trial to determine the effects of psychosocial interventions on morbidity and mortality in coronary heart disease (CHD) patients. The primary objective of this multicenter trial is to evaluate the effects of psychosocial interventions on the cardiac-related morbidity and mortality of MI patients at high psychosocial risk. High psychosocial risk is defined as the presence of depression and/or social isolation. The study design will compare a psychosocial intervention group, in which patients are provided with social support and psychological treatment designed to decrease social isolation and depression, with a health education control and a standard medical care group, using a combined endpoint of CHD death plus reinfarction. Secondary endpoints include health-related quality of life; adherence to medications and health-promoting behaviors; and ischemic events, measured by ambulatory electrocardiogram and exercise tolerance testing. To accomplish its objective, this program proposes to award approximately eight clinical units for patient accession, intervention, and data collection. It is anticipated that a total of 3,000 patients, or approximately 375 patients shall be enrolled per clinical unit. The period of performance is anticipated for six years beginning in August 1995. The Request for Proposal (RFP) NHLBI-HC-94-28 is available and proposals are due November 18, 1994. Offerors other than continental North American institutions will not be considered based on the need for scientifically comparable data. INQUIRIES All requests for this solicitation must be submitted in writing; oral requests must be confirmed either in writing or by FAX. Written requests must include three self-addressed mailing labels, cite RFP NHLBI-HC-94-28, and be sent to: Cheryl A. Jennings Division of Extramural Affairs National Heart, Lung, and Blood Institute 7550 Wisconsin Avenue, Room 3C16 Bethesda, MD 20892 .
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Office of Extramural Research (OER) |
National Institutes of Health (NIH) 9000 Rockville Pike Bethesda, Maryland 20892 |
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