GUIDANCE FOR PRINCIPAL INVESTIGATORS ON THE PREPARATION OFINVESTIGATOR-INITIATED RESEARCH GRANT APPLICATIONS REQUESTING MORE THAN $500,000 IN DIRECT COSTS IN ANY YEAR NIH GUIDE, Volume 22, Number 45, December 17, 1993 P.T. 34 Keywords: Grants Administration/Policy+ National Institutes of Health Applicants planning to submit investigator-initiated research grant applications requesting $500,000 or more in direct costs in any year are advised that it is important that they contact appropriate Institute/Center staff as they begin to develop plans for the study. Applications received without prior staff contact may be delayed in the review process or returned to the applicant without review. Applicants who are uncertain regarding which Institute/Center to contact should call the Referral Office, Division of Research Grants (301-594-7250). .
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