TERMS AND CONDITIONS OF AWARD FOR LARGE SCALE UNSOLICITED RESEARCHPROJECT APPLICATIONS FOR CLINICAL TRIALS, PREVENTION AND CONTROL INTERVENTIONS, AND EPIDEMIOLOGICAL STUDIES NIH GUIDE, Volume 22, Number 45, December 17, 1993 P.T. 34 Keywords: Grants Administration/Policy+ Clinical Trial Epidemiology Disease Prevention+ Disease Control+ National Cancer Institute The National Cancer Institute (NCI) would like to clarify the above-titled Notice published in the NIH Guide, Vol. 22, No. 43, November 26, 1993, as follows: The first sentence of the first paragraph is modified as follows: The National Cancer Institute (NCI) announces that any new or competing continuation R01 investigator-initiated clinical trial, prevention or control intervention, or epidemiological study in which direct costs exceed $500,000 in any year (at a single institution or in the aggregate for a study proposing multi-institutional collaborative arrangements submitted as either subcontracts to a single application or as separate applications) will usually be awarded only as a cooperative agreement (U01). The remainder of the published Notice stating the policy is unchanged. Program project (P01) grant applications are thus excluded from the policy and will continue to be accepted by the NCI according to current guidelines. .
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