IN UTERO STEM CELL TRANSPLANTATION FOR GENETIC DISEASES

NIH GUIDE, Volume 22, Number 30, August 20, 1993



RFA:  HL-93-014



P.T. 34



Keywords:

  Blood Diseases 

  Transplantation of Organs 

  Disease Model 

  Genetics 

  Metabolic Diseases 



National Heart, Lung and Blood Institute

National Institute of Diabetes and Digestive and Kidney Diseases



Letter of Intent Receipt Date:  October 1, 1993

Application Receipt Date:  November 17, 1993



The National Institute of Diabetes and Digestive and Kidney Diseases

(NIDDK) will join with the National, Heart, Lung and Blood Institute

(NHLBI) to co-sponsor the Request for Applications (RFA) HL-93-014

entitled "In Utero Stem Cell Transplantation for Genetic Disease,"

published in the NIH Guide for Grants and Contracts, Vol. 22, No. 14,

April 9, 1993.  The NIDDK has a continuing interest in the support of

research on the development of in utero stem cell transplantation for

the treatment of genetic metabolic diseases with particular emphasis

on lysosomal storage diseases and mucopolysaccharidoses.  Since these

metabolic diseases have been shown to be ameliorated by postnatal

bone marrow transplants, they would make appropriate model systems

for the development of in utero stem cell transplantation.

Applications received in response to this RFA that propose to treat

genetic metabolic diseases will be considered for funding by both the

NHLBI and the NIDDK.



Interested investigators are encouraged to contact Program Staff to

discuss potential applications and to obtain the full text of the

amended RFA.  Inquiries may be addressed to:



Dr. Catherine McKeon

Division of Diabetes, Endocrinology and Metabolic Diseases

National Institute of Diabetes and Digestive and Kidney Diseases

Westwood Building, Room 621

Bethesda, MD  20892

Telephone:  (301) 594-7582

FAX:  (301) 594-9011



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