TUMOR TISSUE RESOURCES FOR EVALUATION OF PROMISING DIAGNOSTIC ANDPROGNOSTIC APPROACHES NIH Guide, Volume 22, Number 16, April 23, 1993 MAA AVAILABLE: NCI-CB-33050-60 P.T. 34 Keywords: Tissue Culture Diagnosis, Medical Bioassay National Cancer Institute The National Cancer Institute (NCI) is seeking experienced organizations able to access and provide large numbers of paraffin embedded tumor tissues (and where available, frozen tumor specimens) with associated patient follow-up data to be used for the validation of promising new diagnostic and prognostic assays. The tumor tissue required and the assays to be performed will be defined by Master Agreement Orders (MAOs) issued during the period of performance. The MAOs will be based upon competition between members of the Master Agreement (MA) pool. MA Holders who successfully bid on specific MAOs will provide and analyze paraffin blocks from a minimum number of patients with specific tumor stages of breast, colorectal, or bladder cancer and with a minimum number of years of clinical follow-up. MA Holders will perform evaluations of promising new diagnostic and prognostic techniques as defined by individual MAOs. Offerors may qualify to perform one, all, or any combination of the following methodologies: flow cytometry studies of cell proliferation, molecular biology studies, and/or immunohistochemical assays. Multiple MAOs may be issued in each year. The studies to be performed under the MAOs will be designed by the NCI. Publication of results of the studies is expected to reflect the collaborative efforts between MAO Holders and NCI staff. This is the annual resolicitation of RFP Number NCI-CB-21001-32. INQUIRIES Requests for this solicitation must be in writing and reference MAA No. NCI-CB-33050-60. The Master Agreement Announcement (MAA) is now available and responses will be due COB June 4, 1993. Requests are to be addressed to: Barbara P. Birnman, Contract Specialist Research Contracts Branch, CECS National Cancer Institute Executive Plaza South, Suite 620 Bethesda, MD 20892 Telephone: (301) 496-8611 .
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