STUDY OF HEMOCHROMATOSIS IN AFRICAN AMERICANS

NIH Guide, Volume 22, Number 16, April 23, 1993



RFP AVAILABLE:  NICHD-IRP-93-07



P.T. 34, FC



Keywords:

  Metabolic Diseases 

  Biological Resources 



National Institute of Child Health and Human Development



The National Institute of Child Health and Human Development (NICHD) is

planning to conduct a research project to characterize the iron status

and obtain DNA samples from members of African American families that

will be identified by index subjects with iron overload.  These samples

will be used to determine the chromosomal localization of the abnormal

gene associated with hemochromatosis seen in African Americans and to

further elucidate the role of gene regulation on iron metabolism.  The

NICHD seeks a contractor in the Washington metropolitan area to provide

the patient population, research personnel, and support services

required by the Cell Biology and Metabolism Branch (CBMB) to perform

the research associated with this project.  The following mandatory

criteria must be met at the time of source selection: (1) the prime

contractor must have the academic, clinical and scientific environment

required to attract and recruit qualified clinical and basic research

trainees and staff, and to render the services necessary for the

support of clinical and laboratory research conducted by the CBMB; (2)

the prime contractor and any subcontractors must have the ability to

expeditiously transport the samples that have been collected to the

NICHD, Bethesda campus, within six hours of collection, allowing

sufficient time for initial processing at the NICHD laboratories; and

(3) the prime contractor must be within the proximity of the NICHD

Bethesda campus to enable the NICHD staff to access the patient

population.



This announcement is a new solicitation.  It is anticipated that one

cost-reimbursement incrementally funded type of contract will be

awarded under the Request for Proposals (RFP) for a period of four

years.  The issuance of this RFP will be on or about May 3, 1993 and

proposals are due approximately 60 days thereafter.



INQUIRIES



All requests must cite the RFP number above and include two self

addressed mailing labels.  All sources who consider themselves

qualified will be considered.  Those organizations desiring a copy of

the above RFP may send a written or FAX request to:



Ms. Virginia A. DeSAu

Office of Grants and Contracts

National Institute of Child Health and Human Development

6100 Building, Suite 7A07

Bethesda, MD  20892

Telephone:  (301) 496-4611

FAX:  (301) 402-3676



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