NIH GUIDE, Volume 22, Number 5, February 5, 1993

P.T. 34



  Cell Lines 

  Monoclonal Antibodies 

National Center for Research Resources

The National Cell Culture Center is a resource facility that provides

large-scale mammalian cell culture services.  The Center, available

to researchers throughout the United States and Canada, has been

established to alleviate the shortage of facilities and expertise

required to meet the cell culture needs of the biomedical research

community.  The Cell Culture Center is supported by a cooperative

agreement award from the National Center for Research Resources, NIH.

Specifically, the Cell Culture Center supports basic biomedical

research by providing investigators with the following customized


o  Large quantity production of mammalian cells in suspension or

monolayer cultures.  Quantities range from 10 to 300 liters, which

can be provided on a weekly basis.

o  Large quantity production of monoclonal antibodies.  Quantities

range from 0.5 to 100 grams.

o  Large quantity production of non-hybridoma cell secreted proteins.

Quantities vary depending on individual cell lines.

A request form, obtained from the Cell Culture Center, must contain a

description of the relevant research project.  Following approval of

the request by the Cell Culture Center's Scientific Advisory Board,

the applicant's cell line is sent to the Center, and grown to the

requested amount.  Researchers are charged only for the consumable

materials and a portion of the labor costs required for each project.


Direct programmatic inquiries regarding this research resource to:

Louise E. Ramm, Ph.D.

Biological Models and Materials Research Program

National Center for Research Resources

Westwood Building Room 8A07

Bethesda, MD  20892

Telephone:  (301) 402-0630

Direct requests for applications and resource inquiries to:

Dr. Mark Hirschel

Director, National Cell Culture Center

8500 Evergreen Boulevard

Minneapolis, MN  55433

Telephone:  1-800-325-1112


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