ANTIGENIC VARIATION OF HIV-1 AND RELATED LENTIVIRUSES

NIH GUIDE, Volume 21, Number 36, October 9, 1992



RFP AVAILABLE:  NIH-NIAID-DAIDS-93-13



P.T. 34



Keywords:

  Viral Studies (Virology) 

  Immunology 

  Bioassay 

  Biological Resources 



National Institute of Allergy and Infectious Diseases



The Vaccine Research and Development Branch, Basic Research and

Development Program, Division of AIDS, National Institute of Allergy

and Infectious Diseases (NIAID) has a requirement for a contractor to

receive and process virus-infected, human-derived samples on a large

scale basis and to isolate, expand and immunologically characterize

HIV-1 and related lentiviruses from these samples.  Specifically, the

selected contractor will be responsible for:  1) performing virus

isolation, expansion, and characterization from samples supplied to

the Contractor; 2) performing specific immunological assays for HIV

and related lentiviruses; 3) classifying all virus isolates received

into antigenic subgroups based upon serological/immunological assays;

4) securing, receiving, cataloging, processing, and storing samples

from both domestic and international sites, and distributing samples

to other investigators; 5) providing inventory and a Database

Management System; 6) providing facilities and resources; 7)

reporting progress according to reporting requirements; 8) meeting

with the Project Officer; 9) obtaining clearance for publication; and

10) implementing an orderly transition to a successor Contractor.

This is an announcement for an anticipated Request for Proposals

(RFP).  RFP NIH-NIAID-DAIDS-93-13 will be issued on or about October

9, 1992 with a closing date tentatively set for December 22, 1992.

One contract will be awarded as a result of this solicitation.  It is

expected that the contract will have a five-year period of

performance.  A level-of-effort cost-reimbursement contract is

anticipated.  Requests for the RFP shall be directed in writing to:



Chief, Contract Management

Branch, National Institute of Allergy and Infectious Diseases

Solar Building, Room 3C07

Bethesda, MD  20892

FAX:  (301) 402-0972



Please provide this office with three self-addressed mailing labels.

Telephone inquiries will not be honored and all inquiries must be in

writing.  A short-form version of the RFP will be provided first.

That version includes only the statement of work and the Evaluation

Criteria to be used for selection of the awardee.  After examining

this, a full-text version of the RFP must be requested, in writing

for those offerors interested in responding.  FAX requests are

acceptable for the full-text version only.  All proposals from

responsible sources will be considered by the NIAID.  This

advertisement does not commit the Government to award a contract.



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