Notice Number: NOT-RR-05-002
Release Date: December 7, 2004
The National Center for Research Resources (NCRR), National Institutes of Health, will solicit offers for a contract to establish a National Stem Cell Bank (NSCB). The NSCB will acquire, store, characterize and distribute the human embryonic stem cell (hESC) lines currently approved for federal funding, as listed on the NIH Stem Cell Registry (http://stemcells.nih.gov/research/registry/). The NSCB will consolidate the approved hESC lines in one location, will maintain uniform quality control and will reduce the costs that researchers pay for the cell lines. Specifically, the NSCB will: 1) Test the hESC lines in regard to basic characteristics such as karyotypic stability, molecular markers, pluripotency, etc; 2) Characterize patterns of gene expression in the various lines; 3) Determine the capacity to differentiate into specific cell types; 4) Standardize methods for obtaining stable subclones; 5) Develop standardized quality control assays; 6) Provide technical service and training for researchers; 7) Distribute the cells at nominal cost with minimal intellectual property barriers; 8) Make all data publicly available through a website; 9) Coordinate with other entities currently working with approved hESC lines. The NCRR anticipates that the activities of the NSCB will facilitate new investigations using the approved hESC lines, leading to advances in basic knowledge and enhanced opportunities for translational research.
This announcement is not a Request for Proposal (RFP). The RFP will be available electronically on or about December 16, 2004, under RFP No. NIH-NHLBI-RR-05-19 at the following Internet sites: FedBizOpps Website: http://www.fedbizopps.gov; NCRR Website: http://www.ncrr.nih.gov; and NHLBI Website: http://www.nhlbi.nih.gov/funding/inits/index.htm. All information required for the submission of an offer will be contained in the solicitation. Proposals will be due on or about March 16, 2005. It is anticipated that one (1) cost-reimbursement, incrementally funded, completion type contract will be awarded for a period of four (4) years. The anticipated award date is September 15, 2005.
Department of Health and Human Services
National Institutes of Health
National Heart, Lung, and Blood Institute
Contracts Operations Branch
6701 Rockledge Dr.
Room 6100, MSC 7902
Bethesda, MD, 20892-7902
Kristiane Cooper, Contract Specialist
John Taylor, Chief
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
Office of Extramural
National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
Department of Health
and Human Services (HHS)
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