September 7, 2022
PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Office of Research on Women's Health (ORWH)
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute on Drug Abuse (NIDA)
National Institute of Environmental Health Sciences (NIEHS)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Nursing Research (NINR)
National Center for Complementary and Integrative Health (NCCIH)
Sexual and Gender Minority Research Office (SGMRO)
National Cancer Institute (NCI)
All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
Office of Nutrition Research (ONR)
The Office of Research on Women’s Health (ORWH) announces the availability of administrative supplements to support research highlighting health inequities among women in the United States who are understudied, underrepresented and underreported (U3) in biomedical research. Robust studies exploring sex and gender influences and social determinants of health are needed to reduce inequities. The proposed research must address at least one objective from strategic goals 1, 2, or 3 of the “2019-2023 Trans-NIH Strategic Plan for Women’s Health Research, Advancing Science for the Health of Women.”
Women account for over half of the U.S. population, according to the U.S. Census Bureau. Women and girls belonging to certain populations - including, but not limited to, NIH-designated health disparities populations; persons experiencing homelessness, institutionalization, or incarceration; persons having physical, intellectual, or sensory disabilities; and immigrants—bear a disproportionate burden of health risks, disease prevalence, and poorer health outcomes. Additionally, underrepresentation in data reporting and biomedical research hinders unique opportunities to learn more about associations between personal identity, sociocultural factors, and health.
There is a complex intersection of internal biological (e.g., hormonal function) and external social and structural forces (e.g., social determinants of health, experiences of trauma) that play a role in the health status, disease presentation, treatment responses, and health-related quality of life of women across the life course. In 2014, ORWH published “The Women of Color Health Data Book, 4th edition,” which consists of U.S. government-sourced, population-based health, and disease data. This publication highlights the urgent need to improve understanding of the etiologies of health and health care inequities among populations of women disadvantaged by social determinants of health (e.g., racism) and the mechanisms that contribute to the downstream health effects.
This NOSI encourages rigorous experimental designs, as well as the implementation of collaborative interdisciplinary research on the common causes and pathways of ill health and disease, differential risk, morbidity, and mortality, across socioecological domains and levels of influence. To help meet group- and population-level needs with culturally and contextually relevant approaches, this NOSI also encourages thoughtful incorporation of intersectionality into research by applying the NIMHD Minority Health and Health Disparities Research Framework. Lastly, the COVID-19 pandemic has magnified longstanding challenges and barriers. This NOSI will support work to address the challenges faced by women and girls with respect to gendered work, lower paid positions/economic instability, gender-based violence, and unsafe housing—including when they intersect with bias and discrimination associated with race, sexual orientation, disability, age, and socioeconomic status. To strengthen and accelerate multidisciplinary disparities research in women’s health, this opportunity encourages the partnership of junior and senior investigators, as well as experienced women’s health researchers, with those with expertise in health disparities.
Specific Areas of Research Interest
This NOSI will support projects highlighting common sources of inequities in women and girls’ health, with a specific emphasis on those that integrate measures beyond the individual level and consider perspectives from multiple disciplines. A broad range of research topics studied at the preclinical, clinical, behavioral, and translational levels—including proposals incorporating multilevel interventions, using community-engaged approaches, and focusing on one or more NIH-designated health disparities populations—are encouraged.
Topics of interest include, but are not limited to:
Only electronically submitted applications will be accepted.
Note: Specific aims added to the parent grant per SARS-CoV-2/COVID-19 Competitive Revisions process are considered as part of the parent application and are eligible to apply for a supplement under this NOSI.
PDs/PIs of the activity mentioned above codes must also fulfill all the following requirements, otherwise, their applications will be deemed non-responsive to this NOSI.
Scientific Review Process
The NIH program staff will conduct administrative reviews of the application submissions; the most meritorious applications will receive funding consideration pending the availability of funds.
Application and Submission Information
Damiya (Miya) Whitaker, Psy.D., M.A.
Office of Research on Women’s Health (ORWH)