Key Dates

Related Announcements

NOT-DK-24-025 - Notice of Expiration for NIDDK's NOT-DK-24-010 Notice of Special Interest (NOSI): "Administrative Supplements to Enhance Engagement Activity with Underserved Populations Within the Type 1 Diabetes Community (Admin Supp Clinical Trial Not Allowed)"

PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Issued by

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

Sexual and Gender Minority Research Office (SGMRO)

Purpose

Purpose

NIDDK aims to achieve equitable engagement in research across all persons impacted by type 1 diabetes (T1D). Understanding that participation in research is inequitable across many groups impacted by T1D, this supplement opportunity supports activities which enhance outreach to and engagement with underserved populations which experience diabetes-related health disparities. (ref. NIH designated health disparities populations). Improved engagement, participation, and incorporation of leadership from underserved T1D populations is deemed essential for addressing disparities and advancing health equity in T1D outcomes.

This supplement opportunity is available to PD(s)/PI(s) of active NIDDK research grants investigating T1D. Administrative supplements must support work within the scope of the original project and cannot be used to support planning activities for future grants.

Background

The NIDDK’s Strategic Plan highlights the cross-cutting theme of “achieving health equity by eliminating health disparities among racial and ethnic minority populations and others who are underserved.” T1D is one mission disease with significant disparities. Approximately 2 million Americans live with T1D and individuals with less socioeconomic support and those from underserved rural and/or racial and ethnic populations have worse glycemic control, increased complications, and worse quality of life compared to non-minoritized individuals. To address these health disparities, it is paramount that research studies have equitable engagement and participation across all interested parties. Community-engaged research brings to bear the lived experience and expertise of the affected communities, which may yield interventions that are more likely to be appropriate, acceptable, and feasible, and less likely to cause harm. Community engagement that involves trust building, use of culturally appropriate research designs, questions, and materials (i.e., outreach, recruitment, retention, informed consents) is an important method to enhance and assess research outcomes including participation goals, health specific outcomes and sustainability. To this end, NIDDK aims to achieve equitable engagement with a broad array of individuals (including people from NIH designated health disparities populations) in T1D research; particularly those from communities that experience diabetes-related health disparities. Understanding that participation in research is inequitable across many groups impacted by T1D, this supplement opportunity offers support for enhancing engagement with underserved populations.

Research Objectives

Administrative Supplements will support 1 to 2 years of activities which are deemed necessary to strengthen engagement and participation with health disparities communities affected by T1D to enhance the success of the parent project. The purpose of the supplemental activity is to provide additional resources to investigators with active NIDDK T1D human subject research who are not successfully engaging with or recruiting/retaining health disparities populations into the ongoing research study, despite initial engagement efforts. With additional budgetary resources, supplemental activity should strengthen relationships between clinical and/or basic T1D investigators and individuals living with T1D, related care givers, and/or other community and advocate persons with interest in T1D outcomes with the goal of enhancing the deliverables of the active research project.  The engagement activities must aim to improve participation from and community relationships with individuals from NIH designated health disparities populations. Active and meaningful engagement should involve these individuals and/or organizations in the development, design, and execution of the study, as well as in dissemination of findings. Given that these are supplements to existing studies, the activities proposed will vary based on the stage of the study and must be within scope of the parent research project’s initial engagement activity such as approaches for recruitment, retention, or intervention feedback. Also, supported, meaningful engagement must entail more than focus groups, surveys, or other activities where people are only involved as participants or respondents. Rather, engagement approaches must involve bidirectional and sustained communication and interactions that result in informed decision-making about the research activities.

Supported specific activities will include, but are not limited to, the following:

• Direct community engagement activities with health disparities populations. Examples include, patient/caregiver advisory board consultation, execution of listening sessions, interviews for community feedback, engagement studio consultations, community-based events for research education, recruitment, retention, dissemination of research findings.
• Obtaining external expert consultation for guidance with underserved population community relations, engagement, and/or recruitment.

Budget Information

• NIDDK intends to support 4-6 supplements.
• NIDDK will provide support up to $75,000 in direct costs per year for up to 2 years for new community engagement activities beyond what is supported by the parent project. In addition to engagement activities, as described under Research Objectives, funds may be used for travel, presentation and publication costs directly related to the added engagement activities.

Application and Submission Information

Applications for this initiative must be submitted using the following opportunity or its subsequent reissued equivalent.

• PA-20-272 - Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

All instructions in the SF424 (R&R) Application Guide and PA-20-272 must be followed, with the following additions:

• Application Due Date(s) – December 2, 2024, March 3, 2025, by 5:00 PM local time of applicant organization.
• For funding consideration, applicants must include NOT-DK-24-020 in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative.
• Requests may be for up to 2 years of support only.
• The Research Strategy section of the application is limited to 6 pages.
• Only existing awardees of NIDDK program are eligible to apply.
• The proposed project dates must be within the project period of the parent award. 
• Applicants are strongly encouraged to notify the program contact at the Institute supporting the parent award that a request has been submitted in response to this NOFO in order to facilitate efficient processing of the request.

Inquiries

Please direct all inquiries to:

Miranda M. Broadney MD, MPH
Division of Diabetes, Endocrinology and Metabolic Diseases
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Telephone:301-594-1176
Email: [email protected]